Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells
about
Development and evolution of the human neocortexIdentification and selected reaction monitoring (SRM) quantification of endocytosis factors associated with NumbBinding specificity and in vivo targets of the EH domain, a novel protein-protein interaction moduleaPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb.The Mdm2 oncoprotein interacts with the cell fate regulator NumbLNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradationSiah-1 binds and regulates the function of NumbLinking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localizationNumb links extracellular cues to intracellular polarity machinery to promote chemotaxisLoss of negative regulation by Numb over Notch is relevant to human breast carcinogenesisDistinct human NUMB isoforms regulate differentiation vs. proliferation in the neuronal lineageNumb is an endocytic proteinMouse numb is an essential gene involved in cortical neurogenesisInvolvement of fatty acid pathways and cortical interaction of the pronuclear complex in Caenorhabditis elegans embryonic polarityOriented divisions, fate decisionsThe Drosophila cytosine-5 methyltransferase Dnmt2 is associated with the nuclear matrix and can access DNA during mitosisLong-term live cell imaging and automated 4D analysis of drosophila neuroblast lineagesThe Numb/p53 circuitry couples replicative self-renewal and tumor suppression in mammary epithelial cells.dp53 Restrains ectopic neural stem cell formation in the Drosophila brain in a non-apoptotic mechanism involving Archipelago and cyclin ENotch and Prospero repress proliferation following cyclin E overexpression in the Drosophila bristle lineageHedgehog signaling acts with the temporal cascade to promote neuroblast cell cycle exitCoordinating cell polarity and cell cycle progression: what can we learn from flies and worms?Keeping neural progenitor cells on a short leash during Drosophila neurogenesisStructure of a Numb PTB domain-peptide complex suggests a basis for diverse binding specificityMiranda directs Prospero to a daughter cell during Drosophila asymmetric divisionsAsymmetric cell divisionEps15R is a tyrosine kinase substrate with characteristics of a docking protein possibly involved in coated pits-mediated internalizationThe mammalian numb phosphotyrosine-binding domain. Characterization of binding specificity and identification of a novel PDZ domain-containing numb binding protein, LNXThe COP9 signalosome converts temporal hormone signaling to spatial restriction on neural competenceNotch1 signaling stimulates proliferation of immature cardiomyocytesPhosphorylation of Numb regulates its interaction with the clathrin-associated adaptor AP-2Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epitheliumProgenitor cell maintenance requires numb and numblike during mouse neurogenesisDlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epitheliaNeural Stem Cells to Cerebral Cortex: Emerging Mechanisms Regulating Progenitor Behavior and Productivity.PARtitioning numb.Dynamic regulation of mammalian numb by G protein-coupled receptors and protein kinase C activation: Structural determinants of numb association with the cortical membraneHistone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation.Asymmetric self-renewal and commitment of satellite stem cells in muscle.Epicardial spindle orientation controls cell entry into the myocardium
P2860
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P2860
Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells
description
1994 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1994
@ast
im Februar 1994 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1994/02/11)
@sk
vědecký článek publikovaný v roce 1994
@cs
wetenschappelijk artikel (gepubliceerd op 1994/02/11)
@nl
наукова стаття, опублікована в лютому 1994
@uk
مقالة علمية (نشرت في 11-2-1994)
@ar
name
Asymmetric distribution of num ...... stinct fates to daughter cells
@ast
Asymmetric distribution of num ...... stinct fates to daughter cells
@en
Asymmetric distribution of num ...... stinct fates to daughter cells
@nl
type
label
Asymmetric distribution of num ...... stinct fates to daughter cells
@ast
Asymmetric distribution of num ...... stinct fates to daughter cells
@en
Asymmetric distribution of num ...... stinct fates to daughter cells
@nl
prefLabel
Asymmetric distribution of num ...... stinct fates to daughter cells
@ast
Asymmetric distribution of num ...... stinct fates to daughter cells
@en
Asymmetric distribution of num ...... stinct fates to daughter cells
@nl
P2093
P3181
P1433
P1476
Asymmetric distribution of num ...... stinct fates to daughter cells
@en
P2093
P304
P3181
P356
10.1016/0092-8674(94)90112-0
P407
P577
1994-02-11T00:00:00Z