Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia
about
The APC-hDLG complex negatively regulates cell cycle progression from the G0/G1 to S phaseGAKIN, a novel kinesin-like protein associates with the human homologue of the Drosophila discs large tumor suppressor in T lymphocytesPlasma membrane Ca2+-atpase isoforms 2b and 4b interact promiscuously and selectively with members of the membrane-associated guanylate kinase family of PDZ (PSD95/Dlg/ZO-1) domain-containing proteinsGuanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modulesThe MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formationHuman homolog of disc-large is required for adherens junction assembly and differentiation of human intestinal epithelial cellsHDLG5/KIAA0583, encoding a MAGUK-family protein, is a primary progesterone target gene in breast cancer cellsRole of the PDZ domain-binding motif of the oncoprotein E6 in the pathogenesis of human papillomavirus type 31Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor proteinRegulation of the discs large tumor suppressor by a phosphorylation-dependent interaction with the beta-TrCP ubiquitin ligase receptorThe hScrib/Dlg apico-basal control complex is differentially targeted by HPV-16 and HPV-18 E6 proteinsDirect binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like proteinDirect interaction with a kinesin-related motor mediates transport of mammalian discs large tumor suppressor homologue in epithelial cellsA novel and conserved protein-protein interaction domain of mammalian Lin-2/CASK binds and recruits SAP97 to the lateral surface of epitheliaCraniofacial dysmorphogenesis including cleft palate in mice with an insertional mutation in the discs large genePDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membraneIntramolecular interactions regulate SAP97 binding to GKAPRegulation of cadherin adhesive activityDiscs-large homolog 1 regulates smooth muscle orientation in the mouse ureter.The nuclear RhoA exchange factor Net1 interacts with proteins of the Dlg family, affects their localization, and influences their tumor suppressor activityAn atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3Yes-associated protein 65 localizes p62(c-Yes) to the apical compartment of airway epithelia by association with EBP50Cancer stem cell division: when the rules of asymmetry are brokenSpatial and temporal characteristics of normal and perturbed vesicle transportStructural basis for nucleotide-dependent regulation of membrane-associated guanylate kinase-like domainsInsights into Regulated Ligand Binding Sites from the Structure of ZO-1 Src Homology 3-Guanylate Kinase ModuleThe Src Homology 3 Domain Is Required for Junctional Adhesion Molecule Binding to the Third PDZ Domain of the Scaffolding Protein ZO-1Crystal structure of the hCASK PDZ domain reveals the structural basis of class II PDZ domain target recognitionCharacterization of the interaction between protein 4.1R and ZO-2. A possible link between the tight junction and the actin cytoskeletonInteraction of SAP97 with minus-end-directed actin motor myosin VI. Implications for AMPA receptor traffickingInteraction of the tyrosine kinase Pyk2 with the N-methyl-D-aspartate receptor complex via the Src homology 3 domains of PSD-95 and SAP102hINADl/PATJ, a homolog of discs lost, interacts with crumbs and localizes to tight junctions in human epithelial cellshScrib is a functional homologue of the Drosophila tumour suppressor ScribbleDLG5 in cell polarity maintenance and cancer developmentRequirement of PDZ-containing proteins for cell cycle regulation and differentiation in the mouse lens epitheliumDlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligasesOncogenic function for the Dlg1 mammalian homolog of the Drosophila discs-large tumor suppressorDlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization.Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5.Clustering of CARMA1 through SH3-GUK domain interactions is required for its activation of NF-κB signalling.
P2860
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P2860
Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia
description
1996 nî lūn-bûn
@nan
1996 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Dlg protein is required for ju ...... ontrol in Drosophila epithelia
@ast
Dlg protein is required for ju ...... ontrol in Drosophila epithelia
@en
type
label
Dlg protein is required for ju ...... ontrol in Drosophila epithelia
@ast
Dlg protein is required for ju ...... ontrol in Drosophila epithelia
@en
prefLabel
Dlg protein is required for ju ...... ontrol in Drosophila epithelia
@ast
Dlg protein is required for ju ...... ontrol in Drosophila epithelia
@en
P2093
P2860
P356
P1476
Dlg protein is required for ju ...... ontrol in Drosophila epithelia
@en
P2093
P2860
P304
P356
10.1083/JCB.134.6.1469
P407
P577
1996-09-01T00:00:00Z