Calcium channel alpha2delta subunits: differential expression, function, and drug binding
about
Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesisPharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentinA short history of voltage-gated calcium channelsThe Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic PotentialStructure-function of proteins interacting with the α1 pore-forming subunit of high-voltage-activated calcium channelsCaV channels and cancer: canonical functions indicate benefits of repurposed drugs as cancer therapeuticsIon channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac deathAntiallodynic effect of pregabalin in rat models of sympathetically maintained and sympathetic independent neuropathic painThe ß subunit of voltage-gated Ca2+ channelsCentral Mechanisms Mediating Thrombospondin-4-induced Pain States.Pregabalin modulation of neurotransmitter release is mediated by change in intrinsic activation/inactivation properties of ca(v)2.1 calcium channels.The alpha2delta subunits of voltage-gated calcium channels form GPI-anchored proteins, a posttranslational modification essential for functionIdentification of a disulfide bridge essential for structure and function of the voltage-gated Ca(2+) channel α(2)δ-1 auxiliary subunit.Progress in the structural understanding of voltage-gated calcium channel (CaV) function and modulation.Calcium channel auxiliary α2δ and β subunits: trafficking and one step beyond.Presynaptic alpha2delta-3 is required for synaptic morphogenesis independent of its Ca2+-channel functionsA common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization.Identification of the alpha2-delta-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin.New Horizons in the development of antiepileptic drugs: Innovative strategies.Calcium and arrhythmogenesis.Post-stroke pain hypersensitivity induced by experimental thalamic hemorrhage in rats is region-specific and demonstrates limited efficacy of gabapentin.Computer modeling of siRNA knockdown effects indicates an essential role of the Ca2+ channel alpha2delta-1 subunit in cardiac excitation-contraction coupling.The therapeutic potential of Na+ and Ca2+ channel blockers in pain management.Nerve injury-induced calcium channel alpha-2-delta-1 protein dysregulation leads to increased pre-synaptic excitatory input into deep dorsal horn neurons and neuropathic allodyniaNeuronal calcium channels: splicing for optimal performance.Chronic pregabalin inhibits synaptic transmission between rat dorsal root ganglion and dorsal horn neurons in culture.Molecular regulation of voltage-gated Ca2+ channels.Expression of Calcium Channel Subunit Variants in Small Mesenteric Arteries of WKY and SHRVascular calcium channels and high blood pressure: pathophysiology and therapeutic implications.A novel Ca(V)1.2 N terminus expressed in smooth muscle cells of resistance size arteries modifies channel regulation by auxiliary subunits.Voltage-gated calcium channels and idiopathic generalized epilepsies.Regulation of Ca(V)2 calcium channels by G protein coupled receptors.Biological Systems of Vitamin K: A Plasma Nutriproteomics Study of Subclinical Vitamin K Deficiency in 500 Nepalese Children.Disrupting calcium channel expression to lower blood pressure: new targeting of a well-known channelExpression of voltage-gated calcium channel α(2)δ(4) subunits in the mouse and rat retina.α2δ-1 gene deletion affects somatosensory neuron function and delays mechanical hypersensitivity in response to peripheral nerve damage.Targeted disruption of the voltage-dependent calcium channel alpha2/delta-1-subunit.Functional properties of the CaV1.2 calcium channel activated by calmodulin in the absence of alpha2delta subunitsElectrophysiological characterization of spinal neuron sensitization by elevated calcium channel alpha-2-delta-1 subunit protein.Tools for phospho- and glycoproteomics of plasma membranes.
P2860
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P2860
Calcium channel alpha2delta subunits: differential expression, function, and drug binding
description
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im Dezember 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/12/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/12/01)
@nl
наукова стаття, опублікована в грудні 2003
@uk
مقالة علمية (نشرت في ديسمبر 2003)
@ar
name
Calcium channel alpha2delta subunits: differential expression, function, and drug binding
@ast
Calcium channel alpha2delta subunits: differential expression, function, and drug binding
@en
Calcium channel alpha2delta subunits: differential expression, function, and drug binding
@nl
type
label
Calcium channel alpha2delta subunits: differential expression, function, and drug binding
@ast
Calcium channel alpha2delta subunits: differential expression, function, and drug binding
@en
Calcium channel alpha2delta subunits: differential expression, function, and drug binding
@nl
prefLabel
Calcium channel alpha2delta subunits: differential expression, function, and drug binding
@ast
Calcium channel alpha2delta subunits: differential expression, function, and drug binding
@en
Calcium channel alpha2delta subunits: differential expression, function, and drug binding
@nl
P3181
P1476
Calcium channel alpha2delta subunits: differential expression, function, and drug binding
@en
P2093
Else Marais
Franz Hofmann
P304
P3181
P356
10.1023/B:JOBB.0000008028.41056.58
P577
2003-12-01T00:00:00Z
P6179
1013258093