Rhesus monkey TRIM5α SPRY domain recognizes multiple epitopes that span several capsid monomers on the surface of the HIV-1 mature viral core
about
Impact of TRIM5α in vivoStructural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid latticePrimate TRIM5 proteins form hexagonal nets on HIV-1 capsids.Mechanism of B-box 2 domain-mediated higher-order assembly of the retroviral restriction factor TRIM5α.Recognition of the HIV capsid by the TRIM5α restriction factor is mediated by a subset of pre-existing conformations of the TRIM5α SPRY domain.Ring finger protein 39 genetic variants associate with HIV-1 plasma viral loads and its replication in cell culture.Contribution of MxB oligomerization to HIV-1 capsid binding and restrictionThe small-molecule 3G11 inhibits HIV-1 reverse transcription.TRIM5α SPRY/coiled-coil interactions optimize avid retroviral capsid recognition.A general model for retroviral capsid pattern recognition by TRIM5 proteins.The three-fold axis of the HIV-1 capsid lattice is the species-specific binding interface for TRIM5α.
P2860
Q26786870-9DA3435E-E66D-4C0F-A7DE-3B35909D5DCAQ27684490-7AEF8437-5B84-4DAC-82F5-B6E29E3B37E2Q30276687-FDBD8A3E-B478-49CA-A543-8A986577E353Q30276688-47CB59E3-88C5-4A6C-BE37-4D8643E4CC14Q33989616-AF5AF0E9-1D0C-40C3-BD1F-E898063314DDQ34040744-4AED12A8-AF47-491A-BBC0-62126F40A849Q35111033-FC8A3C1A-0AC9-478D-954A-E5CD385D3738Q38740847-E029549A-3586-4B15-BE03-733B585A7C8EQ45070285-6DAE5A51-F570-48E2-8FB9-781466D2E66AQ45074273-78EF46C9-1438-4F8E-91F4-B622480F0B46Q46241874-51675EF0-B8C4-4AD9-80B8-840FA1BC87F1
P2860
Rhesus monkey TRIM5α SPRY domain recognizes multiple epitopes that span several capsid monomers on the surface of the HIV-1 mature viral core
description
2013 nî lūn-bûn
@nan
2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Rhesus monkey TRIM5α SPRY doma ...... of the HIV-1 mature viral core
@ast
Rhesus monkey TRIM5α SPRY doma ...... of the HIV-1 mature viral core
@en
Rhesus monkey TRIM5α SPRY doma ...... of the HIV-1 mature viral core
@nl
type
label
Rhesus monkey TRIM5α SPRY doma ...... of the HIV-1 mature viral core
@ast
Rhesus monkey TRIM5α SPRY doma ...... of the HIV-1 mature viral core
@en
Rhesus monkey TRIM5α SPRY doma ...... of the HIV-1 mature viral core
@nl
prefLabel
Rhesus monkey TRIM5α SPRY doma ...... of the HIV-1 mature viral core
@ast
Rhesus monkey TRIM5α SPRY doma ...... of the HIV-1 mature viral core
@en
Rhesus monkey TRIM5α SPRY doma ...... of the HIV-1 mature viral core
@nl
P2093
P2860
P3181
P1476
Rhesus monkey TRIM5α SPRY doma ...... of the HIV-1 mature viral core
@en
P2093
Akash Bhattacharya
Andrei Tomashevski
Dmitri N Ivanov
Felipe Diaz-Griffero
P2860
P304
P3181
P356
10.1016/J.JMB.2013.07.025
P407
P577
2013-07-23T00:00:00Z