Functional interplay between MDM2, p63/p73 and mutant p53
about
Oncogenic Intra-p53 Family Member Interactions in Human CancersThe Regulation of Tumor Suppressor p63 by the Ubiquitin-Proteasome SystemCombining Oncolytic Virotherapy with p53 Tumor Suppressor Gene TherapyEfficacy and Molecular Mechanisms of Differentiated Response to the Aurora and Angiogenic Kinase Inhibitor ENMD-2076 in Preclinical Models of p53-Mutated Triple-Negative Breast CancerThe role of MDM2 and MDM4 in breast cancer development and prevention.ERβ decreases the invasiveness of triple-negative breast cancer cells by regulating mutant p53 oncogenic function.Transcriptome analysis of follicles reveals the importance of autophagy and hormones in regulating broodiness of Zhedong white goose.Apigenin enhances the cisplatin cytotoxic effect through p53-modulated apoptosis.Aggregation and Prion-Like Properties of Misfolded Tumor Suppressors: Is Cancer a Prion Disease?Mutant p53 in Cancer: Accumulation, Gain-of-Function, and Therapy.p53 Activity Dominates That of p73 upon Mdm4 Loss in Development and Tumorigenesis.Multisite aggregation of p53 and implications for drug rescue.The dominant-negative interplay between p53, p63 and p73: A family affair.Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated TP53 and MDM2 up-regulation.Elevated expression of ΔNp63 in advanced esophageal squamous cell carcinoma.Gain-of-function mutant p53 activates small GTPase Rac1 through SUMOylation to promote tumor progression.Reactivating TP53 signaling by the novel MDM2 inhibitor DS-3032b as a therapeutic option for high-risk neuroblastoma.Intrinsic aggregation propensity of the p63 and p73 TI domains correlates with p53R175H interaction and suggests further significance of aggregation events in the p53 family.MiR-142-3p is downregulated in aggressive p53 mutant mouse models of pancreatic ductal adenocarcinoma by hypermethylation of its locus.Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity.A Role for p53 in the Adaptation to Glutamine Starvation through the Expression of SLC1A3A novel molecular rotor facilitates detection of p53-DNA interactions using the Fluorescent Intercalator Displacement Assay
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P2860
Functional interplay between MDM2, p63/p73 and mutant p53
description
2015 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2015
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im August 2015 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
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wetenschappelijk artikel (gepubliceerd op 2015/08/13)
@nl
наукова стаття, опублікована в серпні 2015
@uk
مقالة علمية (نشرت في 13-8-2015)
@ar
name
Functional interplay between MDM2, p63/p73 and mutant p53
@ast
Functional interplay between MDM2, p63/p73 and mutant p53
@en
type
label
Functional interplay between MDM2, p63/p73 and mutant p53
@ast
Functional interplay between MDM2, p63/p73 and mutant p53
@en
prefLabel
Functional interplay between MDM2, p63/p73 and mutant p53
@ast
Functional interplay between MDM2, p63/p73 and mutant p53
@en
P2093
P2860
P921
P3181
P356
P1433
P1476
Functional interplay between MDM2, p63/p73 and mutant p53
@en
P2093
K. H. Vousden
M. H. Stindt
P. a. J. Muller
R. L. Ludwig
P2860
P2888
P304
P3181
P356
10.1038/ONC.2014.359
P407
P577
2015-08-13T00:00:00Z
P5875
P6179
1011831113