DNA damage in oocytes induces a switch of the quality control factor TAp63α from dimer to tetramer
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Cell density-dependent acetylation of ΔNp63α is associated with p53-dependent cell cycle arrestDNA repair and aging: the impact of the p53 familyStructure and Kinetic Stability of the p63 Tetramerization DomainMechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerizationThe Regulation of Tumor Suppressor p63 by the Ubiquitin-Proteasome SystemOocyte-specific inactivation of Omcg1 leads to DNA damage and c-Abl/TAp63-dependent oocyte death associated with dramatic remodeling of ovarian somatic cellsTracing the evolution of the p53 tetramerization domainFunctional interplay between MDM2, p63/p73 and mutant p53Regulation of p63 protein stability via ubiquitin-proteasome pathway.∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites.Pathological unfoldomics of uncontrolled chaos: intrinsically disordered proteins and human diseasesp53 Isoforms: An Intracellular Microprocessor?p63 steps into the limelight: crucial roles in the suppression of tumorigenesis and metastasisp73 in Cancer.p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53.Pathway Regulation of p63, a Director of Epithelial Cell FateEvolution of p53 transactivation specificity through the lens of a yeast-based functional assaySpecial AT-rich binding protein-2 (SATB2) differentially affects disease-causing p63 mutant proteins.A global analysis of the complex landscape of isoforms and regulatory networks of p63 in human cells and tissues.Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15.Role of p63 in Development, Tumorigenesis and Cancer ProgressionTissue-specific expression of p73 C-terminal isoforms in mice.p63 the guardian of human reproduction.Structural investigations of the p53/p73 homologs from the tunicate species Ciona intestinalis reveal the sequence requirements for the formation of a tetramerization domain.Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level.Damage limitationThe DNA damage response in mammalian oocytes.Analysis of the oligomeric state and transactivation potential of TAp73α.Rescue of platinum-damaged oocytes from programmed cell death through inactivation of the p53 family signaling networkFemale mice with loss-of-function ITCH display an altered reproductive phenotypePositive feedback regulation of p53 transactivity by DNA damage-induced ISG15 modification.Defying DNA double-strand break-induced death during prophase I meiosis by temporal TAp63α phosphorylation regulation in developing mouse oocytes.How the TP53 family proteins TP63 and TP73 contribute to tumorigenesis: regulators and effectors.Epidermal cell junctions and their regulation by p63 in health and disease.Structural Evolution and Dynamics of the p53 Proteins.p73 - constitutively open for business.Non-oncogenic roles of TAp73: from multiciliogenesis to metabolism.Master regulatory role of p63 in epidermal development and disease.Control mechanisms in germ cells mediated by p53 family proteins.A double dealing tale of p63: an oncogene or a tumor suppressor.
P2860
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P2860
DNA damage in oocytes induces a switch of the quality control factor TAp63α from dimer to tetramer
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
DNA damage in oocytes induces ...... TAp63α from dimer to tetramer
@ast
DNA damage in oocytes induces ...... TAp63α from dimer to tetramer
@en
DNA damage in oocytes induces ...... TAp63α from dimer to tetramer
@nl
type
label
DNA damage in oocytes induces ...... TAp63α from dimer to tetramer
@ast
DNA damage in oocytes induces ...... TAp63α from dimer to tetramer
@en
DNA damage in oocytes induces ...... TAp63α from dimer to tetramer
@nl
prefLabel
DNA damage in oocytes induces ...... TAp63α from dimer to tetramer
@ast
DNA damage in oocytes induces ...... TAp63α from dimer to tetramer
@en
DNA damage in oocytes induces ...... TAp63α from dimer to tetramer
@nl
P2093
P2860
P50
P921
P3181
P1433
P1476
DNA damage in oocytes induces ...... TAp63α from dimer to tetramer
@en
P2093
Aycan Sentürk
Bernd Brutschy
Birgit Schäfer
Elisabeth M Zielonka
Florian G Durst
Frank H Niesen
Frank McKeon
Gregor B Deutsch
Hana Kunkel
Jan Hoffmann
P2860
P304
P3181
P356
10.1016/J.CELL.2011.01.013
P407
P577
2011-02-18T00:00:00Z