Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine
about
Diversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular PerspectivesPost-expression strategies for structural investigations of membrane proteins.Large-scale production and protein engineering of G protein-coupled receptors for structural studiesActivation mechanism of endothelin ETB receptor by endothelin-1Regulation of Chemokine Activity - A Focus on the Role of Dipeptidyl Peptidase IV/CD26Conformational states of the full-length glucagon receptorUbiquitin is a versatile scaffold protein for the generation of molecules with de novo binding and advantageous drug-like propertiesSerial femtosecond crystallography opens new avenues for Structural Biology.The Structure of a CXCR4:Chemokine Complex.i-bodies, Human Single Domain Antibodies That Antagonize Chemokine Receptor CXCR4.The Membrane-Proximal Region of C-C Chemokine Receptor Type 5 Participates in the Infection of HIV-1.Design, synthesis, and biological characterization of novel PEG-linked dimeric modulators for CXCR4Signal transmission through the CXC chemokine receptor 4 (CXCR4) transmembrane helices.MIF, a controversial cytokine: a review of structural features, challenges, and opportunities for drug development.Structural Analysis of Chemokine Receptor-Ligand Interactions.Peptide ligand recognition by G protein-coupled receptorsChemokine and chemokine receptor structure and interactions: implications for therapeutic strategies.Interactions of the Chemokine CCL5/RANTES with Medium-Sized Chondroitin Sulfate LigandsDual targeting of the chemokine receptors CXCR4 and ACKR3 with novel engineered chemokines.Distinct CCR7 glycosylation pattern shapes receptor signaling and endocytosis to modulate chemotactic responses.Highly Accurate Structure-Based Prediction of HIV-1 Coreceptor Usage Suggests Intermolecular Interactions Driving TropismExperiment-Guided Molecular Modeling of Protein-Protein Complexes Involving GPCRsIdentification of the Single Immunodominant Region of the Native Human CC Chemokine Receptor 6 Recognized by Mouse Monoclonal Antibodies.Dynamic Cholesterol-Conditioned Dimerization of the G Protein Coupled Chemokine Receptor Type 4.Potent and Broad Inhibition of HIV-1 by a Peptide from the gp41 Heptad Repeat-2 Domain Conjugated to the CXCR4 Amino TerminusDisulfide Trapping for Modeling and Structure Determination of Receptor: Chemokine Complexes.Preparation and Analysis of N-Terminal Chemokine Receptor Sulfopeptides Using Tyrosylprotein Sulfotransferase Enzymes.Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells.Macrophage Migration Inhibitory Factor-CXCR4 Receptor Interactions: EVIDENCE FOR PARTIAL ALLOSTERIC AGONISM IN COMPARISON WITH CXCL12 CHEMOKINE.Discovery and characterization of novel small-molecule CXCR4 receptor agonists and antagonistsStructural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists.Structural basis of ligand interaction with atypical chemokine receptor 3.Core protein: A pleiotropic keystone in the HBV lifecycle.Progress toward rationally designed small-molecule peptide and peptidomimetic CXCR4 antagonists.Viral manipulation of the host immune response.Production of Chemokine/Chemokine Receptor Complexes for Structural Biophysical Studies.What Do Structures Tell Us About Chemokine Receptor Function and Antagonism?Overview and potential unifying themes of the atypical chemokine receptor family.Identifying ligands at orphan GPCRs: current status using structure-based approaches.
P2860
Q26782778-7487C8E4-6894-49E5-AD49-928A060950E8Q26849743-EC13CB85-5AC6-4862-A874-C767B143BC4CQ26866010-DDFD5A41-DDA9-418D-9AE7-81C2AE27C345Q27727996-10C26DA7-4770-49AD-B582-3FA31CEC3C9FQ28072580-9F4E3762-10AB-4CED-8D26-94F590621E2CQ28265667-B1F1E90B-39F1-4CDF-BEF5-525C763424D3Q30316288-C1845102-D194-4BB4-A521-E7CAD9E268FFQ30367012-496E80D7-4D9E-4604-A558-80C6E37EFC29Q30375950-E530F28C-94A7-4ED2-8784-8067A90D5EE5Q30386356-221BAA33-BE93-4903-B7F1-26363BF3692CQ33595068-7264E589-A0C7-4BD2-869A-0069FE60C4E0Q33874555-AB138295-35C8-4B76-B748-E642B606E99EQ34537921-5BFA490E-1273-4125-A1EA-A3371FA0589FQ34543093-B9DF170E-C1A8-4F2D-B2D4-6538020352D3Q34550666-89620E85-B00F-4ECB-8F9E-35A278F7FCA7Q35179408-B929CD56-759D-4823-AE85-1A6EB14BEEEFQ35528569-9982F5C4-BCC7-46EF-9B8D-367FB7926A49Q35685184-E31C65AD-1F43-4208-86C7-99163D80597CQ35718010-720CF709-6CF3-49DC-A14B-4D1BFFD0C4ADQ35906663-86EA9F91-E052-49B7-8CC5-74E5EBFA511EQ35918124-4E45758E-B7E6-40CF-9501-E386E15C5886Q36001149-F56F5C39-3189-435B-9E28-666BE494B5FDQ36059926-9D0EDD0C-5054-4649-96A5-944BCFB201EBQ36182026-69ACC344-42C6-419E-9B99-A2A7E930E065Q36195192-EF6F9E36-A497-4405-B03D-AD69ECCC5C78Q36663709-39ABC667-751F-4B25-89E1-ABD54D23D489Q36756930-A6CF4E5E-6F0E-48A3-89E9-2B0A6CA756E5Q36948524-2AF34BA1-05C8-408B-AC9D-33647A3F57A2Q37117350-596F85AB-D66B-4FE5-A1F1-910C72A24F80Q37125106-A07EDE2C-FD10-45AB-936F-10C53F1D794FQ37173170-B86F7F96-195F-405F-AA38-37CB7B2D7A95Q37507076-9F54B033-1A29-4911-89DE-E791EDBBED1BQ37598462-C486281C-E07D-485D-A046-298E3027EB57Q38541052-9B29C042-9EDF-4633-A40C-40913F37B037Q38542935-0FCE4EE3-142E-4C2B-A602-9325B08A7F27Q38547642-BB4FE067-8ED8-473B-B055-F5CAC2E6CCF8Q38671723-F940E242-D92D-4642-BFA4-FDBED861FE48Q38680670-AA99B18B-CBC6-4BDE-BF54-4786AE99AFFBQ38689110-05978658-D6B7-40AB-A4B0-EDDC7BC5D297Q38720041-FC696EFA-E7F9-4C74-96C0-4957330F7233
P2860
Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine
description
2015 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 2015
@ast
im März 2015 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
wetenschappelijk artikel (gepubliceerd op 2015/03/06)
@nl
наукова стаття, опублікована в березні 2015
@uk
مقالة علمية (نشرت في 6-3-2015)
@ar
name
Structural biology. Crystal st ...... complex with a viral chemokine
@ast
Structural biology. Crystal st ...... complex with a viral chemokine
@en
type
label
Structural biology. Crystal st ...... complex with a viral chemokine
@ast
Structural biology. Crystal st ...... complex with a viral chemokine
@en
prefLabel
Structural biology. Crystal st ...... complex with a viral chemokine
@ast
Structural biology. Crystal st ...... complex with a viral chemokine
@en
P2093
P2860
P50
P3181
P356
P1433
P1476
Structural biology. Crystal st ...... complex with a viral chemokine
@en
P2093
Chong Wang
Chunxia Zhao
Gustavo Fenalti
Gye Won Han
Huixian Wu
Raymond C. Stevens
Tracy M. Handel
Vadim Cherezov
P2860
P304
P3181
P356
10.1126/SCIENCE.1261064
P407
P577
2015-03-06T00:00:00Z