Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists - Test2 - elhamkhani - TriplyDB

Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

http://www.wikidata.org/entity/Q24619974

about

GPCR oligomers in pharmacology and signaling Molecular recognition of CCR5 by an HIV-1 gp120 V3 loop Structure of an agonist-bound human A2A adenosine receptor High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875 Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation Structural basis for the binding of the membrane-proximal C-terminal region of chemokine receptor CCR2 with the cytosolic regulator FROUNT Crystal structure of a lipid G protein-coupled receptor HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4 Structure of the human κ-opioid receptor in complex with JDTic NMR mapping of RANTES surfaces interacting with CCR5 using linked extracellular domains The chemokine receptor CCR1 is constitutively active, which leads to G protein-independent, β-arrestin-mediated internalization Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator Identification of three residues essential for 5-hydroxytryptamine 2A-metabotropic glutamate 2 (5-HT2A·mGlu2) receptor heteromerization and its psychoactive behavioral function Structural model of ligand-G protein-coupled receptor (GPCR) complex based on experimental double mutant cycle data: MT7 snake toxin bound to dimeric hM1 muscarinic receptor Structure of the human histamine H1 receptor complex with doxepin One-step immunopurification and lectinochemical characterization of the Duffy atypical chemokine receptor from human erythrocytes Molecular recognition of CXCR4 by a dual tropic HIV-1 gp120 V3 loop Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist Computational approaches in target identification and drug discovery Basic Pharmacological and Structural Evidence for Class A G-Protein-Coupled Receptor Heteromerization G Protein-Coupled Receptors (GPCRs) in Alzheimer's Disease: A Focus on BACE1 Related GPCRs Homing in hematopoietic stem cells: focus on regulatory role of CXCR7 on SDF1a/CXCR4 axis Engineering therapeutic antibodies targeting G-protein-coupled receptors Synthetic Peptides as Protein Mimics Diversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular Perspectives Structural Studies of G Protein-Coupled Receptors Physiology of the orexinergic/hypocretinergic system: a revisit in 2012 Biased and g protein-independent signaling of chemokine receptors Structure determination of membrane proteins by nuclear magnetic resonance spectroscopy Post-expression strategies for structural investigations of membrane proteins.Diversity and modularity of G protein-coupled receptor structures OX1 and OX2 orexin/hypocretin receptor pharmacogenetics Large-scale production and protein engineering of G protein-coupled receptors for structural studies Metaphors, naming and new signaling paradigms by G-protein-coupled receptors New insights for drug design from the X-ray crystallographic structures of G-protein-coupled receptors Computational approaches for modeling GPCR dimerization Opioid receptors: toward separation of analgesic from undesirable effects Fluorescent approaches for understanding interactions of ligands with G protein coupled receptors Chemokine receptor CXCR2: physiology regulator and neuroinflammation controller?Tools for GPCR drug discovery.

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Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

http://www.wikidata.org/entity/Q24619974

description

2010 nî lūn-bûn

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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年學術文章

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name

Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

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Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

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Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

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Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

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Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

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Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

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Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists

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Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

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Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

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Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

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SCIENCE.1194396

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Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

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Alexei Brooun

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Beili Wu

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Clifford D Mol

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Damon J Hamel

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Ellen Y T Chien

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F Christopher Bi

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Gustavo Fenalti

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Peter Kuhn

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Peter Wells

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Raymond C Stevens

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P2860

Aggregation of RANTES is responsible for its inflammatory properties. Characterization of nonaggregating, noninflammatory RANTES mutants

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

Involvement of chemokine receptors in breast cancer metastasis

The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

Identification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES. Characterization of active disaggregated chemokine variants

Structures of the CCR5 N Terminus and of a Tyrosine-Sulfated Antibody with HIV-1 gp120 and CD4

A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor

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1066-71

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scholarly article

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499199

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10.1126/SCIENCE.1194396

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6007

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330

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Vsevolod Katritch

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2010-11-19T00:00:00Z

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20929726

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G protein-coupled receptor

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3074590

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