The Major Brain Cholesterol Metabolite 24(S)-Hydroxycholesterol Is a Potent Allosteric Modulator of N-Methyl-D-Aspartate Receptors
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Treatment-Resistant Major Depression: Rationale for NMDA Receptors as Targets and Nitrous Oxide as TherapyNMDA receptor modulators: an updated patent review (2013-2014)Persistent Effects of Developmental Exposure to 17α-Ethinylestradiol on the Zebrafish (Danio rerio) Brain Transcriptome and BehaviorPharmacological enhancement of memory or cognition in normal subjectsThe NMDA Receptor and Schizophrenia: From Pathophysiology to Treatment.Different oxysterols have opposing actions at N-methyl-D-aspartate receptors.Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology.The NMDA receptor 'glycine modulatory site' in schizophrenia: D-serine, glycine, and beyond.Cholesterol in brain disease: sometimes determinant and frequently implicated.Interaction between positive allosteric modulators and trapping blockers of the NMDA receptor channel.Disruption of astrocyte-neuron cholesterol cross talk affects neuronal function in Huntington's disease.An Integrated Approach for Screening and Identification of Positive Allosteric Modulators of N-Methyl-D-Aspartate Receptors.Pregnenolone sulfate as a modulator of synaptic plasticity.24S-hydroxycholesterol and 25-hydroxycholesterol differentially impact hippocampal neuronal survival following oxygen-glucose deprivation.Endogenous 24S-hydroxycholesterol modulates NMDAR-mediated function in hippocampal slices.Neuronal cholesterol metabolism increases dendritic outgrowth and synaptic markers via a concerted action of GGTase-I and Trk.LXR Regulation of Brain Cholesterol: From Development to Disease.Chimeric Glutamate Receptor Subunits Reveal the Transmembrane Domain Is Sufficient for NMDA Receptor Pore Properties but Some Positive Allosteric Modulators Require Additional Domains.24(S)-Hydroxycholesterol protects the ex vivo rat retina from injury by elevated hydrostatic pressure.Lovastatin fails to improve motor performance and survival in methyl-CpG-binding protein2-null miceThe bile acid-sensitive ion channel (BASIC), the ignored cousin of ASICs and ENaCProgesterone and its metabolites as therapeutic targets in psychiatric disorders.Lipid dynamics at dendritic spines.24(S)-Hydroxycholesterol as a Modulator of Neuronal Signaling and Survival.In vitro cytochrome P450 46A1 (CYP46A1) activation by neuroactive compounds.Brain Cholesterol Metabolism and Its Defects: Linkage to Neurodegenerative Diseases and Synaptic Dysfunction.New insights in the systemic and molecular underpinnings of general anesthetic actions mediated by γ-aminobutyric acid A receptors.Cholesterol modulates open probability and desensitization of NMDA receptors.Plasma sterols and depressive symptom severity in a population-based cohort.Cholesterol-metabolizing enzyme cytochrome P450 46A1 as a pharmacologic target for Alzheimer's disease.Mechanism and properties of positive allosteric modulation of N-methyl-d-aspartate receptors by 6-alkyl 2-naphthoic acid derivatives.A silver lining for 24-hydroxycholesterol in Alzheimer's disease: The involvement of the neuroprotective enzyme sirtuin 1.Additive neuroprotective effects of 24(S)-hydroxycholesterol and allopregnanolone in an ex vivo rat glaucoma model
P2860
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P2860
The Major Brain Cholesterol Metabolite 24(S)-Hydroxycholesterol Is a Potent Allosteric Modulator of N-Methyl-D-Aspartate Receptors
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2013 nî lūn-bûn
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2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年論文
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2013年論文
@zh-hant
2013年論文
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2013年論文
@zh-mo
2013年論文
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2013年论文
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name
The Major Brain Cholesterol Me ...... N-Methyl-D-Aspartate Receptors
@ast
The Major Brain Cholesterol Me ...... N-Methyl-D-Aspartate Receptors
@en
type
label
The Major Brain Cholesterol Me ...... N-Methyl-D-Aspartate Receptors
@ast
The Major Brain Cholesterol Me ...... N-Methyl-D-Aspartate Receptors
@en
prefLabel
The Major Brain Cholesterol Me ...... N-Methyl-D-Aspartate Receptors
@ast
The Major Brain Cholesterol Me ...... N-Methyl-D-Aspartate Receptors
@en
P2093
P2860
P3181
P1476
The Major Brain Cholesterol Me ...... N-Methyl-D-Aspartate Receptors
@en
P2093
Albert J Robichaud
Andrew J Linsenbardt
Brian Y Chow
Charles F Zorumski
Gabriel M Belfort
Hong-Jin Shu
James J Doherty
Rebecca S Hammond
Steven M Paul
Yukitoshi Izumi
P2860
P304
17290-17300
P3181
P356
10.1523/JNEUROSCI.2619-13.2013
P407
P577
2013-10-30T00:00:00Z