cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain
about
Expression cloning of an oxysterol 7alpha-hydroxylase selective for 24-hydroxycholesterolStructural basis of drug binding to CYP46A1, an enzyme that controls cholesterol turnover in the brainNPC1 and NPC2 regulate cellular cholesterol homeostasis through generation of low density lipoprotein cholesterol-derived oxysterolsABCA1 and scavenger receptor class B, type I, are modulators of reverse sterol transport at an in vitro blood-brain barrier constituted of porcine brain capillary endothelial cellsFGF-1 induces expression of LXRalpha and production of 25-hydroxycholesterol to upregulate the apoE gene in rat astrocytesCrystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brainDo oxysterols control cholesterol homeostasis?Lipid biomarkers of oxidative stress in a genetic mouse model of Smith-Lemli-Opitz syndromeCholesterol 24-hydroxylase: an enzyme of cholesterol turnover in the brain7-Dehydrocholesterol-derived oxysterols and retinal degeneration in a rat model of Smith-Lemli-Opitz syndrome24S-hydroxycholesterol effects on lipid metabolism genes are modeled in traumatic brain injuryImportance of Apolipoprotein A-I in Multiple SclerosisThe role of lipid peroxidation in neurological disordersCholesterol balance in prion diseases and Alzheimer's diseaseBinding of a Cyano- and Fluoro-containing Drug Bicalutamide to Cytochrome P450 46A1: UNUSUAL FEATURES AND SPECTRAL RESPONSECytochrome P450s in the synthesis of cholesterol and bile acids--from mouse models to human diseases.Dual targeting of Osh1p, a yeast homologue of oxysterol-binding protein, to both the Golgi and the nucleus-vacuole junction.Oxysterol 7alpha-hydroxylase (CYP39A1) in the ciliary nonpigmented epithelium of bovine eyePolymorphism in the cholesterol 24S-hydroxylase gene is associated with Alzheimer's diseaseHuman sterol 27-hydroxylase (CYP27) overexpressor transgenic mouse model. Evidence against 27-hydroxycholesterol as a critical regulator of cholesterol homeostasisEnhanced production of 24S-hydroxycholesterol is not sufficient to drive liver X receptor target genes in vivoInactivation of liver X receptor beta leads to adult-onset motor neuron degeneration in male miceCholesterol-24S-hydroxylase (CYP46A1) is specifically expressed in neurons of the neural retinaHistone deacetylase inhibition decreases cholesterol levels in neuronal cells by modulating key genes in cholesterol synthesis, uptake and effluxThe effect of 24S-hydroxycholesterol on cholesterol homeostasis in neurons: quantitative changes to the cortical neuron proteomeThe role of alpha-methylacyl-CoA racemase in bile acid synthesisThe Major Brain Cholesterol Metabolite 24(S)-Hydroxycholesterol Is a Potent Allosteric Modulator of N-Methyl-D-Aspartate ReceptorsRapid birth-death evolution specific to xenobiotic cytochrome P450 genes in vertebratesBrain cholesterol turnover required for geranylgeraniol production and learning in mice.Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function.Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease.Endoplasmic reticulum stress effector CCAAT/enhancer-binding protein homologous protein (CHOP) regulates chronic kidney disease-induced vascular calcification.Summary of information on human CYP enzymes: human P450 metabolism data.Analysis of oxysterols by electrospray tandem mass spectrometry.Method development for the determination of 24S-hydroxycholesterol in human plasma without derivatization by high-performance liquid chromatography with tandem mass spectrometry in atmospheric pressure chemical ionization mode.Potential mechanisms linking cholesterol to Alzheimer's disease-like pathology in rabbit brain, hippocampal organotypic slices, and skeletal muscleNeuronal expression and subcellular localization of cholesterol 24-hydroxylase in the mouse brainMetals and cholesterol: two sides of the same coin in Alzheimer's disease pathology.Cholesterol in the retina: the best is yet to come.Expression profiles of cholesterol metabolism-related genes are altered during development of experimental autoimmune encephalomyelitis in the rat spinal cord.
P2860
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P2860
cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
cDNA cloning of cholesterol 24 ...... terol homeostasis in the brain
@ast
cDNA cloning of cholesterol 24 ...... terol homeostasis in the brain
@en
cDNA cloning of cholesterol 24 ...... terol homeostasis in the brain
@en-gb
cDNA cloning of cholesterol 24 ...... terol homeostasis in the brain
@nl
type
label
cDNA cloning of cholesterol 24 ...... terol homeostasis in the brain
@ast
cDNA cloning of cholesterol 24 ...... terol homeostasis in the brain
@en
cDNA cloning of cholesterol 24 ...... terol homeostasis in the brain
@en-gb
cDNA cloning of cholesterol 24 ...... terol homeostasis in the brain
@nl
prefLabel
cDNA cloning of cholesterol 24 ...... terol homeostasis in the brain
@ast
cDNA cloning of cholesterol 24 ...... terol homeostasis in the brain
@en
cDNA cloning of cholesterol 24 ...... terol homeostasis in the brain
@en-gb
cDNA cloning of cholesterol 24 ...... terol homeostasis in the brain
@nl
P2860
P921
P3181
P356
P1476
cDNA cloning of cholesterol 24 ...... terol homeostasis in the brain
@en
P2093
J M Guileyardo
P2860
P304
P3181
P356
10.1073/PNAS.96.13.7238
P407
P577
1999-06-01T00:00:00Z