The BCL-2 protein family: opposing activities that mediate cell death
about
Genome-wide prediction and validation of peptides that bind human prosurvival Bcl-2 proteinsCaspases in synaptic plasticityThe phosphorylation-dependent regulation of mitochondrial proteins in stress responsesGSK-3β: A Bifunctional Role in Cell Death PathwaysUse of human cancer cell lines mitochondria to explore the mechanisms of BH3 peptides and ABT-737-induced mitochondrial membrane permeabilizationPulmonary proteome and protein networks in response to the herbicide paraquat in ratsIdentification and characterization of GRIM-1, a cell-death-associated gene productActive Bax and Bak are functional holinstBid undergoes multiple conformational changes at the membrane required for Bax activationBAK multimerization for apoptosis, but not bid binding, is inhibited by negatively charged residue in the BAK hydrophobic grooveNoxa/Bcl-2 protein interactions contribute to bortezomib resistance in human lymphoid cellsBcl-x(L) retrotranslocates Bax from the mitochondria into the cytosolMembrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerizationProteins associated with the exon junction complex also control the alternative splicing of apoptotic regulatorsHuman nuclear clusterin mediates apoptosis by interacting with Bcl-XL through C-terminal coiled coil domainIBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activationBH3 domains other than Bim and Bid can directly activate Bax/BakStructural changes in the BH3 domain of SOUL protein upon interaction with the anti-apoptotic protein Bcl-xLParkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated mannerThe hepatitis C virus core protein contains a BH3 domain that regulates apoptosis through specific interaction with human Mcl-1The Apaf-1*procaspase-9 apoptosome complex functions as a proteolytic-based molecular timerCyclin-dependent kinase 1-mediated Bcl-xL/Bcl-2 phosphorylation acts as a functional link coupling mitotic arrest and apoptosisHuman VRK2 modulates apoptosis by interaction with Bcl-xL and regulation of BAX gene expressionVaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligandsThe interferon stimulated gene 54 promotes apoptosisBcl-xL phosphorylation at Ser49 by polo kinase 3 during cell cycle progression and checkpointsBax activates endophilin B1 oligomerization and lipid membrane vesiculationMutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosisIdentification of novel in vivo phosphorylation sites of the human proapoptotic protein BAD: pore-forming activity of BAD is regulated by phosphorylationEndophilin B1/Bif-1 stimulates BAX activation independently from its capacity to produce large scale membrane morphological rearrangementsDeath receptor 6 induces apoptosis not through type I or type II pathways, but via a unique mitochondria-dependent pathway by interacting with Bax proteinBisphenol A and estradiol are equipotent in antagonizing cisplatin-induced cytotoxicity in breast cancer cellsTargeting cellular metabolism to improve cancer therapeuticsCell biology in neuroscience: Death of developing neurons: new insights and implications for connectivityOncolytic specificity of Newcastle disease virus is mediated by selectivity for apoptosis-resistant cellsRole of the c subunit of the FO ATP synthase in mitochondrial permeability transitionBile acids: regulation of apoptosis by ursodeoxycholic acidPaxillin comes of ageMitochondria, cholesterol and cancer cell metabolism
P2860
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P2860
The BCL-2 protein family: opposing activities that mediate cell death
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The BCL-2 protein family: opposing activities that mediate cell death
@ast
The BCL-2 protein family: opposing activities that mediate cell death
@en
type
label
The BCL-2 protein family: opposing activities that mediate cell death
@ast
The BCL-2 protein family: opposing activities that mediate cell death
@en
prefLabel
The BCL-2 protein family: opposing activities that mediate cell death
@ast
The BCL-2 protein family: opposing activities that mediate cell death
@en
P3181
P356
P1476
The BCL-2 protein family: opposing activities that mediate cell death
@en
P2093
Richard J Youle
P2888
P3181
P356
10.1038/NRM2308
P407
P577
2008-01-01T00:00:00Z
P5875
P6179
1038545301