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Reliance of host cholesterol metabolic pathways for the life cycle of hepatitis C virusGenomic convergence among ERRĪ±, PROX1, and BMAL1 in the control of metabolic clock outputsThe 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductasesNovel anti-glioblastoma agents and therapeutic combinations identified from a collection of FDA approved drugsKinetic characterization and phosphoregulation of the Francisella tularensis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase)Human geranylgeranyl diphosphate synthase. cDNA cloning and expressionPrenylated prelamin A interacts with Narf, a novel nuclear proteinMutations in NPC1 highlight a conserved NPC1-specific cysteine-rich domainCrystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysisStatins for children with familial hypercholesterolemiaStatins for children with familial hypercholesterolemiaStatins for women with polycystic ovary syndrome not actively trying to conceiveStatins for children with familial hypercholesterolemiaInterferon-gamma induces major histocompatibility class II transactivator (CIITA), which mediates collagen repression and major histocompatibility class II activation by human aortic smooth muscle cellsNovel members of the human oxysterol-binding protein family bind phospholipids and regulate vesicle transportMutations in the 3beta-hydroxysterol Delta24-reductase gene cause desmosterolosis, an autosomal recessive disorder of cholesterol biosynthesisDefining human ERAD networks through an integrative mapping strategyHuman HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulumExpression of ATP binding cassette-transporter ABCG1 prevents cell death by transporting cytotoxic 7beta-hydroxycholesterolMutant p53 disrupts mammary tissue architecture via the mevalonate pathwayEffects of apoA-V on HDL and VLDL metabolism in APOC3 transgenic micePhosphomevalonate kinase is a cytosolic protein in humansSterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathwaySREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory elementExpression of a novel, sterol-insensitive form of sterol regulatory element binding protein 2 (SREBP2) in male germ cells suggests important cell- and stage-specific functions for SREBP targets during spermatogenesisRoles of rat and human aldo-keto reductases in metabolism of farnesol and geranylgeraniolConservation between human and fungal squalene synthetases: similarities in structure, function, and regulationThe hedgehog receptor patched is involved in cholesterol transportPex19p, a farnesylated protein essential for peroxisome biogenesis.Proteasomal degradation of ubiquitinated Insig proteins is determined by serine residues flanking ubiquitinated lysinesIdentification of farnesoid X receptor beta as a novel mammalian nuclear receptor sensing lanosterolJuxtamembranous aspartic acid in Insig-1 and Insig-2 is required for cholesterol homeostasisCloning and characterization of 1-deoxy-D-xylulose 5-phosphate synthase from Streptomyces sp. Strain CL190, which uses both the mevalonate and nonmevalonate pathways for isopentenyl diphosphate biosynthesisRegulation of HMG-CoA reductase: identification of the site phosphorylated by the AMP-activated protein kinase in vitro and in intact rat liverIdentification and preliminary characterization of protein-cysteine farnesyltransferaseLovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophagesCleavage of sterol regulatory element binding proteins (SREBPs) by CPP32 during apoptosisAdenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotypeReplacement of serine-871 of hamster 3-hydroxy-3-methylglutaryl-CoA reductase prevents phosphorylation by AMP-activated kinase and blocks inhibition of sterol synthesis induced by ATP depletion
P2860
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P2860
description
1990 nĆ® lÅ«n-bĆ»n
@nan
1990 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« ÕÕ„ÕæÖÕøÖÕ”ÖÕ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕøÖÕ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ ÕµÖ
Õ¤ÕøÖÕ”Õ®
@hyw
1990 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« ÖÕ„ÕæÖÕ¾Õ”ÖÕ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
1990幓ć®č«ę
@ja
1990幓č«ę
@yue
1990幓č«ę
@zh-hant
1990幓č«ę
@zh-hk
1990幓č«ę
@zh-mo
1990幓č«ę
@zh-tw
1990幓č®ŗę
@wuu
name
Regulation of the mevalonate pathway
@ast
Regulation of the mevalonate pathway
@en
type
label
Regulation of the mevalonate pathway
@ast
Regulation of the mevalonate pathway
@en
prefLabel
Regulation of the mevalonate pathway
@ast
Regulation of the mevalonate pathway
@en
P3181
P356
P1433
P1476
Regulation of the mevalonate pathway
@en
P2093
Goldstein JL
P2888
P304
P3181
P356
10.1038/343425A0
P407
P577
1990-02-01T00:00:00Z
P6179
1047196635