Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum - Test2 - elhamkhani - TriplyDB

Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum

Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum

http://www.wikidata.org/entity/Q24298901

about

Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps TEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulum A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation The RBCC gene RFP2 (Leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD Defining human ERAD networks through an integrative mapping strategy SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates Mannose trimming is required for delivery of a glycoprotein from EDEM1 to XTP3-B and to late endoplasmic reticulum-associated degradation steps A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin A luminal flavoprotein in endoplasmic reticulum-associated degradation CYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligases The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP Ubiquitin-specific protease 25 functions in Endoplasmic Reticulum-associated degradation RNF185 is a novel E3 ligase of endoplasmic reticulum-associated degradation (ERAD) that targets cystic fibrosis transmembrane conductance regulator (CFTR)Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin'A deubiquitinase negatively regulates retro-translocation of nonubiquitinated substrates HRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradation Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane.The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site E2-25K mediates US11-triggered retro-translocation of MHC class I heavy chains in a permeabilized cell system HECT and RING finger families of E3 ubiquitin ligases at a glance HIV-1 Vpu targets cell surface markers CD4 and BST-2 through distinct mechanisms Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7)One step at a time: endoplasmic reticulum-associated degradation An amphipathic helix targets serum and glucocorticoid-induced kinase 1 to the endoplasmic reticulum-associated ubiquitin-conjugation machinery Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3 Rheumatoid arthritis as a hyper-endoplasmic-reticulum-associated degradation disease Targeting p97 to Disrupt Protein Homeostasis in Cancer Ubiquitylation of an ERAD substrate occurs on multiple types of amino acids Glycoprotein Quality Control and Endoplasmic Reticulum Stress Recent technical developments in the study of ER-associated degradation Selective destruction of abnormal proteins by ubiquitin-mediated protein quality control degradation Mechanisms for quality control of misfolded transmembrane proteins Ubiquitin ligases in cholesterol metabolism The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology Ubiquitination-induced fluorescence complementation (UiFC) for detection of K48 ubiquitin chains in vitro and in live cells Allosteric Activation of E2-RING Finger-Mediated Ubiquitylation by a Structurally Defined Specific E2-Binding Region of gp78 Solution structure and dynamics of human ubiquitin conjugating enzyme Ube2g2 Role of endoplasmic reticulum stress in rheumatoid arthritis pathogenesis.

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P2860

Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum

http://www.wikidata.org/entity/Q24298901

description

2004 nî lūn-bûn

@nan

2004 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

Human HRD1 is an E3 ubiquitin ...... from the endoplasmic reticulum

@ast

Human HRD1 is an E3 ubiquitin ...... from the endoplasmic reticulum

@en

Human HRD1 is an E3 ubiquitin ...... from the endoplasmic reticulum

@en-gb

Human HRD1 is an E3 ubiquitin ...... from the endoplasmic reticulum

@nl

type

label

Human HRD1 is an E3 ubiquitin ...... from the endoplasmic reticulum

@ast

Human HRD1 is an E3 ubiquitin ...... from the endoplasmic reticulum

@en

Human HRD1 is an E3 ubiquitin ...... from the endoplasmic reticulum

@en-gb

Human HRD1 is an E3 ubiquitin ...... from the endoplasmic reticulum

@nl

prefLabel

Human HRD1 is an E3 ubiquitin ...... from the endoplasmic reticulum

@ast

Human HRD1 is an E3 ubiquitin ...... from the endoplasmic reticulum

@en

Human HRD1 is an E3 ubiquitin ...... from the endoplasmic reticulum

@en-gb

Human HRD1 is an E3 ubiquitin ...... from the endoplasmic reticulum

@nl

P1433

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P3181

P356

P1433

Journal of Biological Chemistry

P1476

Human HRD1 is an E3 ubiquitin ...... from the endoplasmic reticulum

@en

P2093

Emmanuel Wiertz

http://www.w3.org/2001/XMLSchema#string

Gerco Hassink

http://www.w3.org/2001/XMLSchema#string

Joseph Roitelman

http://www.w3.org/2001/XMLSchema#string

Min Dai

http://www.w3.org/2001/XMLSchema#string

Rachel Avner

http://www.w3.org/2001/XMLSchema#string

Ram Doolman

http://www.w3.org/2001/XMLSchema#string

Sjaak van Voorden

http://www.w3.org/2001/XMLSchema#string

Swapna Thanedar

http://www.w3.org/2001/XMLSchema#string

Vincent Chau

http://www.w3.org/2001/XMLSchema#string

P2860

The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum

Human HRD1 protects against ER stress-induced apoptosis through ER-associated degradation

Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

HUGE: a database for human large proteins identified in the Kazusa cDNA sequencing project

Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha

A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation

Immunological evidence for eight spans in the membrane domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for enzyme degradation in the endoplasmic reticulum

A simple method for displaying the hydropathic character of a protein

Crystal structure of a class I ubiquitin conjugating enzyme (Ubc7) from Saccharomyces cerevisiae at 2.9 angstroms resolution

P304

3525-34

http://www.w3.org/2001/XMLSchema#string

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scholarly article

P3181

4317947

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P356

10.1074/JBC.M307453200

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P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

279

http://www.w3.org/2001/XMLSchema#string

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Marjolein Kikkert

P577

2004-01-30T00:00:00Z

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P698

14593114

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P921

protein K48-linked ubiquitination

Ubiquitin conjugating enzyme E2 D2

Ubiquitin conjugating enzyme E2 G1

endoplasmic reticulum