about
A critical role for the transcription factor Scl in platelet production during stress thrombopoiesisThe ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stabilityUBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activityFbxw7 regulates lipid metabolism and cell fate decisions in the mouse liverArs2 links the nuclear cap-binding complex to RNA interference and cell proliferationRUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory elementA tale of three fingers: the family of mammalian Sp/XKLF transcription factorsInducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnantsSIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during agingInactivation of Icmt inhibits transformation by oncogenic K-Ras and B-RafLigand-activated site-specific recombination in miceOsteoclast differentiation factor RANKL controls development of progestin-driven mammary cancerTargeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clustersConditional c-myb knockout in adult hematopoietic stem cells leads to loss of self-renewal due to impaired proliferation and accelerated differentiationEndothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in miceMN1-TEL myeloid oncoprotein expressed in multipotent progenitors perturbs both myeloid and lymphoid growth and causes T-lymphoid tumors in miceConditional MN1-TEL knock-in mice develop acute myeloid leukemia in conjunction with overexpression of HOXA9Protein ISGylation modulates the JAK-STAT signaling pathwayInterference with immunoglobulin (Ig)alpha immunoreceptor tyrosine-based activation motif (ITAM) phosphorylation modulates or blocks B cell development, depending on the availability of an Igbeta cytoplasmic tailSmad4 is critical for self-renewal of hematopoietic stem cellsOct4 expression is not required for mouse somatic stem cell self-renewalSignal transducers and activators of transcription as regulators of growth, apoptosis and breast development.Basal immunoglobulin signaling actively maintains developmental stage in immature B cells.Enhanced cell-permeant Cre protein for site-specific recombination in cultured cellsDo we now have a relevant animal model for breast cancer?Simple and straightforward construction of a mouse gene targeting vector using in vitro transposition reactionsMutant loxP vectors for selectable marker recycle and conditional knock-outsTwo major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathioneConditional gene expression in the mouse inner ear using Cre-loxP.Expanding the scope of site-specific recombinases for genetic and metabolic engineeringS1P control of endothelial integrityStrategies to achieve conditional gene mutation in miceImmunological responses and actin dynamics in macrophages are controlled by N-cofilin but are independent from ADFDose-dependent role of the cohesin complex in normal and malignant hematopoiesis.The NF-κB subunit RelA/p65 is dispensable for successful liver regeneration after partial hepatectomy in micePTEN-deficient intestinal stem cells initiate intestinal polyposis.NKT cell-TCR expression activates conventional T cells in vivo, but is largely dispensable for mature NKT cell biologyCXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance.Oncogenic Kras initiates leukemia in hematopoietic stem cellsGrowth factor independence 1b (gfi1b) is important for the maturation of erythroid cells and the regulation of embryonic globin expression
P2860
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P2860
description
1995 nî lūn-bûn
@nan
1995 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Inducible gene targeting in mice
@ast
Inducible gene targeting in mice
@en
type
label
Inducible gene targeting in mice
@ast
Inducible gene targeting in mice
@en
prefLabel
Inducible gene targeting in mice
@ast
Inducible gene targeting in mice
@en
P2093
P3181
P356
P1433
P1476
Inducible gene targeting in mice
@en
P2093
P304
P3181
P356
10.1126/SCIENCE.7660125
P407
P577
1995-09-01T00:00:00Z