Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
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Mood disorders in Huntington's disease: from behavior to cellular and molecular mechanismsThe Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcriptionSCAMP5 links endoplasmic reticulum stress to the accumulation of expanded polyglutamine protein aggregates via endocytosis inhibitionA human HAP1 homologue. Cloning, expression, and interaction with huntingtinpARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular traffickingHIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid systemHuntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicityProtein 4.1B contributes to the organization of peripheral myelinated axonsClioquinol down-regulates mutant huntingtin expression in vitro and mitigates pathology in a Huntington's disease mouse model.Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase.Short-sequence DNA repeats in prokaryotic genomesHuntingtin in health and diseaseThe Gln-Ala repeat transcriptional activator CA150 interacts with huntingtin: neuropathologic and genetic evidence for a role in Huntington's disease pathogenesisTissue transglutaminase overexpression does not modify the disease phenotype of the R6/2 mouse model of Huntington's diseaseHuman single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's diseaseLongitudinal brain changes in early-onset psychosisBile acids in treatment of ocular diseaseThe HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice.Age-dependent alterations of corticostriatal activity in the YAC128 mouse model of Huntington diseaseInteraction between neuronal intranuclear inclusions and promyelocytic leukemia protein nuclear and coiled bodies in CAG repeat diseasesTransgenic models of Huntington's diseaseMolecular pathology of dentatorubral-pallidoluysian atrophyAsialoerythropoietin is not effective in the R6/2 line of Huntington's disease miceEuploidy in somatic cells from R6/2 transgenic Huntington's disease miceCorticostriatal Dysfunction in Huntington's Disease: The BasicsPost-Translational Modifications of Histones in Vertebrate NeurogenesisNeural and mesenchymal stem cells in animal models of Huntington's disease: past experiences and future challengesNew Insights on Astrocyte Ion Channels: Critical for Homeostasis and Neuron-Glia SignalingAsparaginase treatment side-effects may be due to genes with homopolymeric Asn codons (Review-Hypothesis)Nucleolar dysfunction in Huntington's diseaseDysregulation of glutathione homeostasis in neurodegenerative diseasesDefining the role of the Bcl-2 family proteins in Huntington's diseaseRole of cerebral cortex in the neuropathology of Huntington's diseaseHuntington's disease: the past, present, and future search for disease modifiers.Transgenic animal models for study of the pathogenesis of Huntington's disease and therapyMouse models of polyglutamine diseases: review and data table. Part I5-Hydroxymethylcytosine: A new player in brain disorders?Pluripotent stem cells models for Huntington's disease: prospects and challengesIntrabodies as neuroprotective therapeuticsModeling Huntington's disease with induced pluripotent stem cells
P2860
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P2860
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
description
1996 nî lūn-bûn
@nan
1996 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Exon 1 of the HD gene with an ...... l phenotype in transgenic mice
@ast
Exon 1 of the HD gene with an ...... l phenotype in transgenic mice
@en
type
label
Exon 1 of the HD gene with an ...... l phenotype in transgenic mice
@ast
Exon 1 of the HD gene with an ...... l phenotype in transgenic mice
@en
prefLabel
Exon 1 of the HD gene with an ...... l phenotype in transgenic mice
@ast
Exon 1 of the HD gene with an ...... l phenotype in transgenic mice
@en
P2093
P3181
P1433
P1476
Exon 1 of the HD gene with an ...... l phenotype in transgenic mice
@en
P2093
C Hetherington
K Sathasivam
L Mangiarini
S W Davies
P304
P3181
P356
10.1016/S0092-8674(00)81369-0
P407
P577
1996-11-01T00:00:00Z