Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice - Test2 - elhamkhani - TriplyDB

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

http://www.wikidata.org/entity/Q29615357

about

Mood disorders in Huntington's disease: from behavior to cellular and molecular mechanisms The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription SCAMP5 links endoplasmic reticulum stress to the accumulation of expanded polyglutamine protein aggregates via endocytosis inhibition A human HAP1 homologue. Cloning, expression, and interaction with huntingtin pARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity Protein 4.1B contributes to the organization of peripheral myelinated axons Clioquinol down-regulates mutant huntingtin expression in vitro and mitigates pathology in a Huntington's disease mouse model.Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase.Short-sequence DNA repeats in prokaryotic genomes Huntingtin in health and disease The Gln-Ala repeat transcriptional activator CA150 interacts with huntingtin: neuropathologic and genetic evidence for a role in Huntington's disease pathogenesis Tissue transglutaminase overexpression does not modify the disease phenotype of the R6/2 mouse model of Huntington's disease Human single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's disease Longitudinal brain changes in early-onset psychosis Bile acids in treatment of ocular disease The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice.Age-dependent alterations of corticostriatal activity in the YAC128 mouse model of Huntington disease Interaction between neuronal intranuclear inclusions and promyelocytic leukemia protein nuclear and coiled bodies in CAG repeat diseases Transgenic models of Huntington's disease Molecular pathology of dentatorubral-pallidoluysian atrophy Asialoerythropoietin is not effective in the R6/2 line of Huntington's disease mice Euploidy in somatic cells from R6/2 transgenic Huntington's disease mice Corticostriatal Dysfunction in Huntington's Disease: The Basics Post-Translational Modifications of Histones in Vertebrate Neurogenesis Neural and mesenchymal stem cells in animal models of Huntington's disease: past experiences and future challenges New Insights on Astrocyte Ion Channels: Critical for Homeostasis and Neuron-Glia Signaling Asparaginase treatment side-effects may be due to genes with homopolymeric Asn codons (Review-Hypothesis)Nucleolar dysfunction in Huntington's disease Dysregulation of glutathione homeostasis in neurodegenerative diseases Defining the role of the Bcl-2 family proteins in Huntington's disease Role of cerebral cortex in the neuropathology of Huntington's disease Huntington's disease: the past, present, and future search for disease modifiers.Transgenic animal models for study of the pathogenesis of Huntington's disease and therapy Mouse models of polyglutamine diseases: review and data table. Part I 5-Hydroxymethylcytosine: A new player in brain disorders?Pluripotent stem cells models for Huntington's disease: prospects and challenges Intrabodies as neuroprotective therapeutics Modeling Huntington's disease with induced pluripotent stem cells

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P2860

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

http://www.wikidata.org/entity/Q29615357

description

1996 nî lūn-bûn

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1996 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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1996 թվականի նոյեմբերին հրատարակված գիտական հոդված

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1996年の論文

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1996年論文

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1996年論文

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1996年論文

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1996年論文

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1996年論文

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1996年论文

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