pARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking
about
Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington diseaseHuntingtin Is Required for Epithelial Polarity through RAB11A-Mediated Apical Trafficking of PAR3-aPKCHuntingtin's function in axonal transport is conserved in Drosophila melanogasterDominant-Negative Effects of Adult-Onset Huntingtin Mutations Alter the Division of Human Embryonic Stem Cells-Derived Neural CellsThe regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation.The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signalling.Huntingtin protein is essential for mitochondrial metabolism, bioenergetics and structure in murine embryonic stem cellsImpaired brain energy metabolism in the BACHD mouse model of Huntington's disease: critical role of astrocyte-neuron interactions.Lack of interleukin-1 type 1 receptor enhances the accumulation of mutant huntingtin in the striatum and exacerbates the neurological phenotypes of Huntington's disease mice.Transcriptome analysis of newt lens regeneration reveals distinct gradients in gene expression patterns.Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis.Huntington's Disease: From Mutant Huntingtin Protein to Neurotrophic Factor Therapy.Postnatal loss of hap1 reduces hippocampal neurogenesis and causes adult depressive-like behavior in mice.Huntingtin proteolysis releases non-polyQ fragments that cause toxicity through dynamin 1 dysregulation.Inhibition of Aggregation of Mutant Huntingtin by Nucleic Acid Aptamers In Vitro and in a Yeast Model of Huntington's DiseaseEditorial: Golgi Pathology in Neurodegenerative Diseases.Huntingtin regulates mammary stem cell division and differentiation.Unraveling the Role of Huntingtin in Breast Cancer Metastasis.Characterization of axonal transport defects in Drosophila Huntingtin mutants.RNA Aptamers Rescue Mitochondrial Dysfunction in a Yeast Model of Huntington’s Disease.The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients
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pARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking
description
2010 nî lūn-bûn
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2010 թուականին հրատարակուած գիտական յօդուած
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2010年の論文
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name
pARIS-htt: an optimised expres ...... ired for vesicular trafficking
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pARIS-htt: an optimised expres ...... ired for vesicular trafficking
@en
pARIS-htt: an optimised expres ...... ired for vesicular trafficking
@en-gb
pARIS-htt: an optimised expres ...... ired for vesicular trafficking
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label
pARIS-htt: an optimised expres ...... ired for vesicular trafficking
@ast
pARIS-htt: an optimised expres ...... ired for vesicular trafficking
@en
pARIS-htt: an optimised expres ...... ired for vesicular trafficking
@en-gb
pARIS-htt: an optimised expres ...... ired for vesicular trafficking
@nl
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pARIS-htt: an optimised expres ...... ired for vesicular trafficking
@ast
pARIS-htt: an optimised expres ...... ired for vesicular trafficking
@en
pARIS-htt: an optimised expres ...... ired for vesicular trafficking
@en-gb
pARIS-htt: an optimised expres ...... ired for vesicular trafficking
@nl
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pARIS-htt: an optimised expres ...... ired for vesicular trafficking
@en
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Frédéric Saudou
Ghislaine Poizat
Guy Keryer
Maria Molina-Calavita
Raúl Pardo
Sandrine Humbert
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P2888
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10.1186/1756-6606-3-17
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2010-01-01T00:00:00Z
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1033674725