WNT and beta-catenin signalling: diseases and therapies - Test2 - elhamkhani - TriplyDB

WNT and beta-catenin signalling: diseases and therapies

WNT and beta-catenin signalling: diseases and therapies

http://www.wikidata.org/entity/Q29616159

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A novel role for Wnt/Ca2+ signaling in actin cytoskeleton remodeling and cell motility in prostate cancer A lentivirus-mediated genetic screen identifies dihydrofolate reductase (DHFR) as a modulator of beta-catenin/GSK3 signaling Adenomatous polyposis coli (APC) is required for normal development of skin and thymus A deep investigation into the adipogenesis mechanism: profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/beta-catenin signaling pathway Regulation of norrin receptor frizzled-4 by Wnt2 in colon-derived cells Identification of two novel activities of the Wnt signaling regulator Dickkopf 3 and characterization of its expression in the mouse retina R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6 Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysis FoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signaling Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling Histone H1 recruitment by CHD8 is essential for suppression of the Wnt-β-catenin signaling pathway A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling An LRP5 receptor with internal deletion in hyperparathyroid tumors with implications for deregulated WNT/beta-catenin signaling Modulation of LRP6-mediated Wnt signaling by molecular chaperone Mesd Small molecule inhibitors of Wnt/beta-catenin/lef-1 signaling induces apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation The EDD E3 ubiquitin ligase ubiquitinates and up-regulates beta-catenin.WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation Oncogenic function of DACT1 in colon cancer through the regulation of β-catenin Microsomal prostaglandin E synthase-1 promotes hepatocarcinogenesis through activation of a novel EGR1/β-catenin signaling axis Functional analysis of novel phosphorylation sites of CREB-binding protein using mass spectrometry and mammalian two-hybrid assays Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells A coated vesicle-associated kinase of 104 kDa (CVAK104) induces lysosomal degradation of frizzled 5 (Fzd5)The pseudoreceptor BMP and activin membrane-bound inhibitor positively modulates Wnt/beta-catenin signaling TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells Identification of a novel Wnt5a-CK1ɛ-Dvl2-Plk1-mediated primary cilia disassembly pathway LEF-1 negatively controls interleukin-4 expression through a proximal promoter regulatory element Dapper1 is a nucleocytoplasmic shuttling protein that negatively modulates Wnt signaling in the nucleus The Meckel-Gruber Syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation Protein kinase A-mediated 14-3-3 association impedes human Dapper1 to promote dishevelled degradation Kindlin 2 forms a transcriptional complex with β-catenin and TCF4 to enhance Wnt signalling Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1 Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation WNT10A missense mutation associated with a complete odonto-onycho-dermal dysplasia syndrome The tuberous sclerosis complex Shared molecular mechanisms regulate multiple catenin proteins: canonical Wnt signals and components modulate p120-catenin isoform-1 and additional p120 subfamily members.Transcription factor Zic2 inhibits Wnt/β-catenin protein signaling

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WNT and beta-catenin signalling: diseases and therapies

http://www.wikidata.org/entity/Q29616159

description

2004 nî lūn-bûn

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2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

WNT and beta-catenin signalling: diseases and therapies

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WNT and beta-catenin signalling: diseases and therapies

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type

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WNT and beta-catenin signalling: diseases and therapies

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WNT and beta-catenin signalling: diseases and therapies

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prefLabel

WNT and beta-catenin signalling: diseases and therapies

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WNT and beta-catenin signalling: diseases and therapies

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Nature Reviews Genetics

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WNT and beta-catenin signalling: diseases and therapies

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P2093

De Ferrari GV

http://www.w3.org/2001/XMLSchema#string

Kaykas A

http://www.w3.org/2001/XMLSchema#string

Kohn AD

http://www.w3.org/2001/XMLSchema#string

Moon RT

http://www.w3.org/2001/XMLSchema#string

P2860

Inhibition of adipogenesis by Wnt signaling

Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma

Mutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerization

Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy

Homozygous WNT3 mutation causes tetra-amelia in a large consanguineous family

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

Mutations in LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11q.

Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair

Wnt4 overexpression disrupts normal testicular vasculature and inhibits testosterone synthesis by repressing steroidogenic factor 1/beta-catenin synergy

Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation

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691-701

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10.1038/NRG1427

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9

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8343014

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1033736546

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15372092

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