Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
about
Use of human cancer cell lines mitochondria to explore the mechanisms of BH3 peptides and ABT-737-induced mitochondrial membrane permeabilizationCardiolipin switch in mitochondria: shutting off the reduction of cytochrome C and turning on the peroxidase activityDual function of mitochondrial Nm23-H4 protein in phosphotransfer and intermembrane lipid transfer: a cardiolipin-dependent switchCytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factorsActive Bax and Bak are functional holinsInteraction with a membrane surface triggers a reversible conformational change in Bax normally associated with induction of apoptosisBcl-x(L) retrotranslocates Bax from the mitochondria into the cytosolMembrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerizationHuman nuclear clusterin mediates apoptosis by interacting with Bcl-XL through C-terminal coiled coil domainProapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.Heterodimerization of BAK and MCL-1 activated by detergent micellesBH3 domains other than Bim and Bid can directly activate Bax/BakRole of Bim in apoptosis induced in H460 lung tumor cells by the spindle poison Combretastatin-A4Clusterin inhibits apoptosis by interacting with activated BaxThe mitochondrial TOM complex is required for tBid/Bax-induced cytochrome c releaseIdentification of novel in vivo phosphorylation sites of the human proapoptotic protein BAD: pore-forming activity of BAD is regulated by phosphorylationEndophilin B1/Bif-1 stimulates BAX activation independently from its capacity to produce large scale membrane morphological rearrangementsMAP-1 is a mitochondrial effector of Bax.Oligomeric Bax is a component of the putative cytochrome c release channel MAC, mitochondrial apoptosis-induced channelMitochondrial carrier homolog 2 is a target of tBID in cells signaled to die by tumor necrosis factor alpha.Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosisPharmacological manipulation of cell death: clinical applications in sight?Endoplasmic reticulum stress: cell life and death decisions.The Bcl-2 apoptotic switch in cancer development and therapyThe NRIF3 family of transcriptional coregulators induces rapid and profound apoptosis in breast cancer cellsBcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapyProapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activityPhosphatidylethanolamine critically supports internalization of cell-penetrating protein C inhibitorAltered Traffic of Cardiolipin during Apoptosis: Exposure on the Cell Surface as a Trigger for "Antiphospholipid Antibodies"Mechanisms of drug-induced liver injuryA new view of the lethal apoptotic poreBAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial poreThe BCL2 Family: Key Mediators of the Apoptotic Response to Targeted Anticancer TherapeuticsApoptotic agentsCardiolipin and its different properties in mitophagy and apoptosisMitochondria and mitophagy: the yin and yang of cell death controlIntegration and oligomerization of Bax protein in lipid bilayers characterized by single molecule fluorescence studyAutomated microinjection of recombinant BCL-X into mouse zygotes enhances embryo developmentBAX activation is initiated at a novel interaction siteCrystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein
P2860
Q21562635-551B4EEB-2B95-4A65-AC53-E97C82C82F64Q23916927-B802F213-DF61-4A19-A2FE-C0401ACF9D2EQ23923053-B2D7CF56-7EC0-4CF6-AE86-27AD5A632B70Q23923171-6EEE6AE3-E874-4A7C-882A-BE8CFCFDF313Q24293539-3D354B42-7EBB-495D-A606-143E4E6B150EQ24296781-92D9C85A-F165-4441-8D42-6679B70B9A85Q24298758-8CDD9B40-AE06-4083-BEA3-EBFCF2D75E94Q24300125-F2895BFD-D9E4-4201-9E80-E8494ED80584Q24302151-3DB42DAA-F9CC-4E48-9AC7-5550C3F09DF8Q24302494-D333E38C-6D59-4AE6-8D23-475DE3CDA60CQ24305060-980E6C3A-8712-4937-B5C2-B173595C9596Q24305138-42D34EF0-222B-4BC4-B5B4-86D2CCE340AAQ24306494-AFB30B96-1F6D-4754-A6ED-9DA42464DA50Q24316499-23692352-B7A4-4E07-B5A5-B5747FF273A1Q24319971-6560DA34-22E7-4B21-A225-F77CA7F07D42Q24323069-C3DB1D23-C1B2-4A74-9400-C72060DF4E31Q24324817-98077FAA-C1E0-4B80-87D7-6BDE4E232C14Q24337383-8EC46B21-D3F3-41FF-9155-B3419901D93AQ24523479-4FD94756-8543-44DA-BEA8-2B16A3FE9CBFQ24529078-D7462853-73C6-4B9C-B0CD-FAA097B5C8B2Q24534937-45A9C696-4B33-41B3-8CB1-EE0B84BCE757Q24536101-DFD4847C-4EDE-473E-9C5F-E536347099C1Q24536108-3EB5BCFC-9880-42D7-9B66-0ADAFCCDE7E3Q24620437-C9F41179-EF63-4824-BB69-A13FED2FF780Q24623349-DB3950AB-98B5-40E0-9CA6-B78E6AA474A1Q24635408-D1A43CED-8C59-4532-947D-2E94E27FC4EFQ24675444-DFCA3E65-39FC-44CF-B9FD-FD8F1E64FF14Q24676276-7E7D86FA-6DDF-490B-B1EB-6CF186E6F3C0Q26780481-DC5DC90F-4E96-48BC-A4CF-7F53AF6D3693Q26998806-17158AE2-7A09-4DBC-B424-A7E53B4060B3Q27000479-F38195B7-BEEE-4B55-AB99-8C6B967122FCQ27002044-BCC7177C-4026-43FF-ACCA-EC73CB10DF3DQ27010154-0EFCF45C-1645-4280-B5E8-BEDC66E7F938Q27016160-ACC85E7E-C2D1-4E50-A093-F3CBAE7114E3Q27024440-4BEFF05E-0C8B-42B6-B39A-22F5FEA5984BQ27028020-B7063E97-2618-4062-A826-76312D0143B6Q27314915-2D32F887-EDB6-44AC-8BF8-147881657F5FQ27333935-A2C079B2-11DC-415E-87AF-B14C05FF020DQ27652635-564E7C16-B516-41F1-8A4B-CDC7C32CE92CQ27677125-01DD691D-AFAD-45CB-A58C-E55394774AFA
P2860
Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Bid, Bax, and lipids cooperate ...... e outer mitochondrial membrane
@ast
Bid, Bax, and lipids cooperate ...... e outer mitochondrial membrane
@en
type
label
Bid, Bax, and lipids cooperate ...... e outer mitochondrial membrane
@ast
Bid, Bax, and lipids cooperate ...... e outer mitochondrial membrane
@en
prefLabel
Bid, Bax, and lipids cooperate ...... e outer mitochondrial membrane
@ast
Bid, Bax, and lipids cooperate ...... e outer mitochondrial membrane
@en
P2093
P3181
P1433
P1476
Bid, Bax, and lipids cooperate ...... e outer mitochondrial membrane
@en
P2093
Donald D Newmeyer
Guy Perkins
Mark H Ellisman
Martin Latterich
Mason R Mackey
Tomomi Kuwana
P304
P3181
P356
10.1016/S0092-8674(02)01036-X
P407
P577
2002-11-01T00:00:00Z