Targeted disruption of the Rad51 gene leads to lethality in embryonic mice - Test2 - elhamkhani - TriplyDB

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

http://www.wikidata.org/entity/Q29618278

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Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control Evidence for simultaneous protein interactions between human Rad51 paralogs The RAD51 family member, RAD51L3, is a DNA-stimulated ATPase that forms a complex with XRCC2 Mre11 complex and DNA replication: linkage to E2F and sites of DNA synthesis Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells WRN interacts physically and functionally with the recombination mediator protein RAD52 A novel nucleic acid-binding protein that interacts with human rad51 recombinase Isolation of novel human and mouse genes of the recA/RAD51 recombination-repair gene family Regulation of Rad51 function by c-Abl in response to DNA damage The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair Differential effects of Rad52p overexpression on gene targeting and extrachromosomal homologous recombination in a human cell line Human 100-kDa homologous DNA-pairing protein is the splicing factor PSF and promotes DNA strand invasion Fission yeast rad51 and dmc1, two efficient DNA recombinases forming helical nucleoprotein filaments The Arabidopsis homologue of Xrcc3 plays an essential role in meiosis A role for RAD54B in homologous recombination in human cells Interaction of human recombination proteins Rad51 and Rad54 Interaction of human rad51 recombination protein with single-stranded DNA binding protein, RPA Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae Origins and evolution of the recA/RAD51 gene family: evidence for ancient gene duplication and endosymbiotic gene transfer A cell cycle-specific requirement for the XRCC1 BRCT II domain during mammalian DNA strand break repair Overexpression of human RAD51 and RAD52 reduces double-strand break-induced homologous recombination in mammalian cells Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase BRCA1 and BRCA2 proteins: roles in health and disease XRCC3 promotes homology-directed repair of DNA damage in mammalian cells Mouse embryonic stem cells, but not somatic cells, predominantly use homologous recombination to repair double-strand DNA breaks Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein More than blood, a novel gene required for mammalian postimplantation development Complex formation by the human RAD51C and XRCC3 recombination repair proteins Historical overview: searching for replication help in all of the rec places The BRCA2 gene product functionally interacts with p53 and RAD51 Human Rif1 protein binds aberrant telomeres and aligns along anaphase midzone microtubules Homologous Recombination and Its Role in Carcinogenesis Role of BRCA gene dysfunction in breast and ovarian cancer predisposition.Differential and collaborative actions of Rad51 paralog proteins in cellular response to DNA damage.m-Calpain is required for preimplantation embryonic development in mice.Ring of Change: CDC48/p97 Drives Protein Dynamics at Chromatin DNA Damage Signalling and Repair Inhibitors: The Long-Sought-After Achilles' Heel of Cancer Cross talk of tyrosine kinases with the DNA damage signaling pathways Nucleases in homologous recombination as targets for cancer therapy Double-strand break repair on sex chromosomes: challenges during male meiotic prophase

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Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

http://www.wikidata.org/entity/Q29618278

description

1996 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

1996 թվականի հունիսին հրատարակված գիտական հոդված

@hy

article publié dans les Procee ...... f the United States of America

@fr

artículu científicu espublizáu en 1996

@ast

im Juni 1996 veröffentlichter wissenschaftlicher Artikel

@de

scientific article (publication date: 25 June 1996)

@en

wetenschappelijk artikel (gepubliceerd op 1996/06/25)

@nl

наукова стаття, опублікована в червні 1996

@uk

مقالة علمية (نشرت في 25-6-1996)

@ar

name

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

@ast

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

@en

type

label

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

@ast

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

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prefLabel

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

@ast

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

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PNAS.93.13.6236

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Proceedings of the National Academy of Sciences of the United States of America

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Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

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Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA

Biochemistry of homologous recombination in Escherichia coli

The structure of the E. coli recA protein monomer and polymer

Functional differences and interactions among the putative RecA homologs Rad51, Rad55, and Rad57.

Complex formation in yeast double-strand break repair: participation of Rad51, Rad52, Rad55, and Rad57 proteins

Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein

Altering the genome by homologous recombination

Genetic interaction between hoxb-5 and hoxb-6 is revealed by nonallelic noncomplementation

Targeted disruption of the even-skipped gene, evx1, causes early postimplantation lethality of the mouse conceptus

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

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