Human USP18 deficiency underlies type 1 interferonopathy leading to severe pseudo-TORCH syndrome.
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Type I interferon-mediated monogenic autoinflammation: The type I interferonopathies, a conceptual overviewAssessment of Type I Interferon Signaling in Pediatric Inflammatory Disease.Microglia contribute to normal myelinogenesis and to oligodendrocyte progenitor maintenance during adulthood.Type-I interferon pathway in neuroinflammation and neurodegeneration: focus on Alzheimer's disease.STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling.Microglia-dependent synapse loss in type I interferon-mediated lupus.Geoepidemiology and Immunologic Features of Autoinflammatory Diseases: a Comprehensive Review.Microglial Interferon Signaling and White Matter.Exome and genome sequencing for inborn errors of immunity.Structural basis of the specificity of USP18 toward ISG15.Understanding Human Autoimmunity and Autoinflammation Through Transcriptomics.The role of peripheral immune cells in the CNS in steady state and disease.Ontogeny and homeostasis of CNS myeloid cells.Type I interferon pathway in CNS homeostasis and neurological disorders.Microglia in steady state.SOCS1 is an inducible negative regulator of IFN lambda induced gene expression in vivo.ISGylation - a key to lock the cell gates for preventing the spread of threats.Alcohol Fuels Hepatitis C Virus Propensity for Infection in ISGylation/Proteasome-Dependent Manner.USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA.Type I Interferons in Newborns-Neurotoxicity versus Antiviral Defense.Deciphering of the Human Interferon-Regulated Proteome by Mass Spectrometry-Based Quantitative Analysis Reveals Extent and Dynamics of Protein Induction and Repression.Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner.Type I interferon-mediated autoinflammation due to DNase II deficiency.The Role of Interferon in Persistent Viral Infection: Insights from Murine Norovirus.How USP18 deals with ISG15-modified proteins: structural basis for the specificity of the protease.A commentary on band-like calcification with simplified gyration and polymicrogyria: report of 10 new families and identification of five novel OCLN mutations.Regulation of Cellular Antiviral Signaling by Modifications of Ubiquitin and Ubiquitin-like Molecules.Transmembrane protein pUL50 of human cytomegalovirus inhibits ISGylation by downregulating UBE1L.The classification, genetic diagnosis and modelling of monogenic autoinflammatory disordersAcute microglia ablation induces neurodegeneration in the somatosensory system
P2860
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P2860
Human USP18 deficiency underlies type 1 interferonopathy leading to severe pseudo-TORCH syndrome.
description
2016 nî lūn-bûn
@nan
2016 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Human USP18 deficiency underli ...... severe pseudo-TORCH syndrome.
@ast
Human USP18 deficiency underli ...... severe pseudo-TORCH syndrome.
@en
type
label
Human USP18 deficiency underli ...... severe pseudo-TORCH syndrome.
@ast
Human USP18 deficiency underli ...... severe pseudo-TORCH syndrome.
@en
prefLabel
Human USP18 deficiency underli ...... severe pseudo-TORCH syndrome.
@ast
Human USP18 deficiency underli ...... severe pseudo-TORCH syndrome.
@en
P2093
P2860
P50
P356
P1476
Human USP18 deficiency underli ...... severe pseudo-TORCH syndrome.
@en
P2093
Aida Bertoli Avella
Daphne Heijsman
Dusan Bogunovic
Frans W Verheijen
Grazia M S Mancini
Grétel Oudesluijs
Marco Prinz
Rob Willemsen
Rutger W W Brouwer
P2860
P304
P356
10.1084/JEM.20151529
P407
P50
P577
2016-06-20T00:00:00Z