UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity
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ISG15 inhibits Nedd4 ubiquitin E3 activity and enhances the innate antiviral responseUbp43 regulates BCR-ABL leukemogenesis via the type 1 interferon receptor signalingInnate immune responses in hepatitis C virus infectionReceptor dimerization dynamics as a regulatory valve for plasticity of type I interferon signalingISG15 deficiency and increased viral resistance in humans but not miceWeaning Markedly Affects Transcriptome Profiles and Peyer's Patch Development in Piglet Ileum.Interferon signaling and treatment outcome in chronic hepatitis CAlpha Interferon Induces Long-Lasting Refractoriness of JAK-STAT Signaling in the Mouse Liver through Induction of USP18/UBP43Structural and dynamic determinants of type I interferon receptor assembly and their functional interpretation.Interferons and viruses: an evolutionary arms race of molecular interactionsStructural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1Protein Interferon-Stimulated Gene 15 Conjugation Delays but Does Not Overcome Coronavirus Proliferation in a Model of Fulminant HepatitisHuman USP18 deficiency underlies type 1 interferonopathy leading to severe pseudo-TORCH syndrome.Usp18 regulates epidermal growth factor (EGF) receptor expression and cancer cell survival via microRNA-7.Live cell micropatterning reveals the dynamics of signaling complexes at the plasma membraneInterferon induction and function at the mucosal surface.echinus, required for interommatidial cell sorting and cell death in the Drosophila pupal retina, encodes a protein with homology to ubiquitin-specific proteases.Screen for ISG15-crossreactive deubiquitinases.HyperISGylation of Old World monkey ISG15 in human cells.Epstein-Barr virus independent dysregulation of UBP43 expression alters interferon-stimulated gene expression in Burkitt lymphoma.IFN-λ receptor 1 expression is induced in chronic hepatitis C and correlates with the IFN-λ3 genotype and with nonresponsiveness to IFN-α therapiesCombining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon α-induced early antiviral signalling.IFN-λ4 potently blocks IFN-α signalling by ISG15 and USP18 in hepatitis C virus infection.The herpesvirus associated ubiquitin specific protease, USP7, is a negative regulator of PML proteins and PML nuclear bodies.USP18-based negative feedback control is induced by type I and type III interferons and specifically inactivates interferon α response.Transcription analysis on response of swine lung to H1N1 swine influenza virus.Induction and evasion of innate antiviral responses by hepatitis C virus.Search for specific biomarkers of IFNβ bioactivity in patients with multiple sclerosis.Blockade of the ubiquitin protease UBP43 destabilizes transcription factor PML/RARα and inhibits the growth of acute promyelocytic leukemiaInterferon-stimulated genes: a complex web of host defenses.Systemic cytokine and interferon responsiveness Patterns in HIV and HCV mono and co-infectionsSelective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistanceUBE1L represses PML/RAR{alpha} by targeting the PML domain for ISG15ylationActivation of interferon signaling pathways in spinal cord astrocytes from an ALS mouse model.Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation.Usp18 driven enforced viral replication in dendritic cells contributes to break of immunological tolerance in autoimmune diabetes.Virus-like particles activate type I interferon pathways to facilitate post-exposure protection against Ebola virus infection.Tyrosine phosphorylation of protein kinase D2 mediates ligand-inducible elimination of the Type 1 interferon receptor.A robust type I interferon gene signature from blood RNA defines quantitative but not qualitative differences between three major IFNβ drugs in the treatment of multiple sclerosis.Modulation of the host interferon response and ISGylation pathway by B. pertussis filamentous hemagglutinin
P2860
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P2860
UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
UBP43 is a novel regulator of ...... ts ISG15 isopeptidase activity
@ast
UBP43 is a novel regulator of ...... ts ISG15 isopeptidase activity
@en
UBP43 is a novel regulator of ...... ts ISG15 isopeptidase activity
@en-gb
UBP43 is a novel regulator of ...... ts ISG15 isopeptidase activity
@nl
type
label
UBP43 is a novel regulator of ...... ts ISG15 isopeptidase activity
@ast
UBP43 is a novel regulator of ...... ts ISG15 isopeptidase activity
@en
UBP43 is a novel regulator of ...... ts ISG15 isopeptidase activity
@en-gb
UBP43 is a novel regulator of ...... ts ISG15 isopeptidase activity
@nl
prefLabel
UBP43 is a novel regulator of ...... ts ISG15 isopeptidase activity
@ast
UBP43 is a novel regulator of ...... ts ISG15 isopeptidase activity
@en
UBP43 is a novel regulator of ...... ts ISG15 isopeptidase activity
@en-gb
UBP43 is a novel regulator of ...... ts ISG15 isopeptidase activity
@nl
P2093
P2860
P3181
P356
P1433
P1476
UBP43 is a novel regulator of ...... ts ISG15 isopeptidase activity
@en
P2093
Dong-Er Zhang
Jiann-Kae Luo
K G Suresh Kumar
Keun Il Kim
Oxana A Malakhova
Serge Y Fuchs
Weiguo Zou
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7601149
P407
P577
2006-06-07T00:00:00Z