Mutational analysis of the regulatory function of the c-Abl Src homology 3 domain.

Mutational analysis of the regulatory function of the c-Abl Src homology 3 domain.

Item
http://www.wikidata.org/entity/Q30167708
Cdo binds Abl to promote p38alpha/beta mitogen-activated protein kinase activity and myogenic differentiationA unique set of SH3-SH3 interactions controls IB1 homodimerization.A direct binding site for Grb2 contributes to transformation and leukemogenesis by the Tel-Abl (ETV6-Abl) tyrosine kinaseMolecular dynamics and protein function.Mutation of Vav1 adaptor region reveals a new oncogenic activation.Interfacial water molecules in SH3 interactions: Getting the full picture on polyproline recognition by protein-protein interaction domains.Tyrosine phosphorylation in the SH3 domain disrupts negative regulatory interactions within the c-Abl kinase core.Regulation of RhoGEF activity by intramolecular and intermolecular SH3 domain interactions.Assay development and high-throughput screening of small molecular c-Abl kinase activators.Clinical resistance to the kinase inhibitor STI-571 in chronic myeloid leukemia by mutation of Tyr-253 in the Abl kinase domain P-loopActivity of dual SRC-ABL inhibitors highlights the role of BCR/ABL kinase dynamics in drug resistance.The Hippo pathway kinase Lats2 prevents DNA damage-induced apoptosis through inhibition of the tyrosine kinase c-Abl.Identification and characterization of activating ABL1 1b kinase mutations: impact on sensitivity to ATP-competitive and allosteric ABL1 inhibitors.Atomic view of the energy landscape in the allosteric regulation of Abl kinase.
P2860

Mutational analysis of the regulatory function of the c-Abl Src homology 3 domain.

Item
http://www.wikidata.org/entity/Q30167708
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Mutational analysis of the regulatory function of the c-Abl Src homology 3 domain.
@ast
Mutational analysis of the regulatory function of the c-Abl Src homology 3 domain.
@en
type
label
Mutational analysis of the regulatory function of the c-Abl Src homology 3 domain.
@ast
Mutational analysis of the regulatory function of the c-Abl Src homology 3 domain.
@en
prefLabel
Mutational analysis of the regulatory function of the c-Abl Src homology 3 domain.
@ast
Mutational analysis of the regulatory function of the c-Abl Src homology 3 domain.
@en
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P407
P433
P478
P577
P5875
P6179
P698
P356
P1433
P1476
Mutational analysis of the regulatory function of the c-Abl Src homology 3 domain.
@en
P2093
P2860
P2888
P304
P31
P356
P407
P433
P478
P577
P5875
P6179
P698