BRCA1 modulates ionizing radiation-induced nuclear focus formation by the replication protein A p34 subunit.
about
Interaction between BRCA2 and replication protein A is compromised by a cancer-predisposing mutation in BRCA2The 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor genePreferential localization of hyperphosphorylated replication protein A to double-strand break repair and checkpoint complexes upon DNA damageUncovering packaging features of co-regulated modules based on human protein interaction and transcriptional regulatory networksPhosphatidyl inositol 3-kinase-like serine/threonine protein kinases (PIKKs) are required for DNA damage-induced phosphorylation of the 32 kDa subunit of replication protein A at threonine 21.Functions of human replication protein A (RPA): from DNA replication to DNA damage and stress responsesFANCJ (BACH1) helicase forms DNA damage inducible foci with replication protein A and interacts physically and functionally with the single-stranded DNA-binding protein.DNA double strand break repair and its association with inherited predispositions to breast cancerCo-operation of BRCA1 and POH1 relieves the barriers posed by 53BP1 and RAP80 to resectionTumor-associated antigen arrays for the serological diagnosis of cancer.BRCA1-Ku80 protein interaction enhances end-joining fidelity of chromosomal double-strand breaks in the G1 phase of the cell cycleElevated Expression of RPA3 Is Involved in Gastric Cancer Tumorigenesis and Associated with Poor Patient Survival.Replication Protein A 3 Is Associated with Hepatocellular Carcinoma Tumorigenesis and Poor Patient Survival.Opposing roles for 53BP1 during homologous recombination.DNA damage induces p53-dependent BRCA1 nuclear export.
P2860
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P2860
BRCA1 modulates ionizing radiation-induced nuclear focus formation by the replication protein A p34 subunit.
description
2002 nî lūn-bûn
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2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
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2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
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2002年學術文章
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name
BRCA1 modulates ionizing radia ...... ication protein A p34 subunit.
@ast
BRCA1 modulates ionizing radia ...... ication protein A p34 subunit.
@en
type
label
BRCA1 modulates ionizing radia ...... ication protein A p34 subunit.
@ast
BRCA1 modulates ionizing radia ...... ication protein A p34 subunit.
@en
prefLabel
BRCA1 modulates ionizing radia ...... ication protein A p34 subunit.
@ast
BRCA1 modulates ionizing radia ...... ication protein A p34 subunit.
@en
P2860
P356
P1476
BRCA1 modulates ionizing radia ...... ication protein A p34 subunit.
@en
P2093
Shailesh K Choudhary
P2860
P304
P356
10.1002/JCB.10081
P577
2002-01-01T00:00:00Z