Mass spectroscopic characterization of protein modification by 4-hydroxy-2-(E)-nonenal and 4-oxo-2-(E)-nonenal.
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4-Hydroxy-nonenal-A Bioactive Lipid Peroxidation ProductCyclooxygenase-2-mediated DNA damageProtein modifications by electrophilic lipoxidation products: adduct formation, chemical strategies and tandem mass spectrometry for their detection and identificationProtein adducts of aldehydic lipid peroxidation products identification and characterization of protein adducts using an aldehyde/keto-reactive probe in combination with mass spectrometryReactions of electrophiles with nucleophilic thiolate sites: relevance to pathophysiological mechanisms and remediationModification of Cytochrome c by 4-hydroxy- 2-nonenal: evidence for histidine, lysine, and arginine-aldehyde adducts.Protein damage by reactive electrophiles: targets and consequencesCovalent cross-linking of glutathione and carnosine to proteins by 4-oxo-2-nonenal.Charge-derivatized amino acids facilitate model studies on protein side-chain modifications by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.Mass spectrometric evidence for the existence of distinct modifications of different proteins by 2(E),4(E)-decadienalCharacterization of scavengers of gamma-ketoaldehydes that do not inhibit prostaglandin biosynthesis.A mass spectrometric analysis of 4-hydroxy-2-(E)-nonenal modification of cytochrome c.Proteins modified by the lipid peroxidation aldehyde 9,12-dioxo-10(E)-dodecenoic acid in MCF7 breast cancer cells.Proteomic identification of carbonylated proteins and their oxidation sitesSmall molecule activators of the heat shock response: chemical properties, molecular targets, and therapeutic promise.Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation.The lipid peroxidation product 4-hydroxy-2-nonenal: Advances in chemistry and analysisIsotope-coded dimethyl tagging for differential quantification of posttranslational protein carbonylation by 4-hydroxy-2-nonenal, an end-product of lipid peroxidation.Oxidative and reductive metabolism of lipid-peroxidation derived carbonyls.Application of the Hard and Soft, Acids and Bases (HSAB) theory to toxicant--target interactions.Membrane-mediated amyloidogenesis and the promotion of oxidative lipid damage by amyloid beta proteinsModification of platelet proteins by 4-hydroxynonenal: Potential Mechanisms for inhibition of aggregation and metabolismCovalent adducts arising from the decomposition products of lipid hydroperoxides in the presence of cytochrome c.Characterization of a lipid hydroperoxide-derived RNA adduct in rat intestinal epithelial cells.Identification of proteins adducted by lipid peroxidation products in plasma and modifications of apolipoprotein A1 with a novel biotinylated phospholipid probe.Global analysis of protein damage by the lipid electrophile 4-hydroxy-2-nonenalDetoxification reactions: relevance to aging.The essential role of ERK in 4-oxo-2-nonenal-mediated cytotoxicity in SH-SY5Y human neuroblastoma cells.High-resolution mass spectrometry analysis of protein oxidations and resultant loss of functionOxidative stress in diabetes and Alzheimer's disease.Molecular mechanisms of 4-hydroxy-2-nonenal and acrolein toxicity: nucleophilic targets and adduct formation.Mass spectrometric characterization of protein modification by the products of nonenzymatic oxidation of linoleic acid.Fluorescent detection of lipid peroxidation derived protein adducts upon in-vitro cigarette smoke exposure.A novel lipid hydroperoxide-derived cyclic covalent modification to histone H4.Human alpha-1-microglobulin is covalently bound to kynurenine-derived chromophores.Inactivation of human liver bile acid CoA:amino acid N-acyltransferase by the electrophilic lipid, 4-hydroxynonenal.
P2860
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P2860
Mass spectroscopic characterization of protein modification by 4-hydroxy-2-(E)-nonenal and 4-oxo-2-(E)-nonenal.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Mass spectroscopic characteriz ...... nenal and 4-oxo-2-(E)-nonenal.
@ast
Mass spectroscopic characteriz ...... nenal and 4-oxo-2-(E)-nonenal.
@en
type
label
Mass spectroscopic characteriz ...... nenal and 4-oxo-2-(E)-nonenal.
@ast
Mass spectroscopic characteriz ...... nenal and 4-oxo-2-(E)-nonenal.
@en
prefLabel
Mass spectroscopic characteriz ...... nenal and 4-oxo-2-(E)-nonenal.
@ast
Mass spectroscopic characteriz ...... nenal and 4-oxo-2-(E)-nonenal.
@en
P2093
P356
P1476
Mass spectroscopic characteriz ...... nenal and 4-oxo-2-(E)-nonenal.
@en
P2093
Lawrence M Sayre
Paul E Minkler
Zhongfa Liu
P304
P356
10.1021/TX0300030
P577
2003-07-01T00:00:00Z