Network modeling of TGFβ signaling in hepatocellular carcinoma epithelial-to-mesenchymal transition reveals joint sonic hedgehog and Wnt pathway activation
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Mechanisms of TGFβ-Induced Epithelial-Mesenchymal TransitionSignal Transduction Pathways of EMT Induced by TGF-β, SHH, and WNT and Their CrosstalksHedgehog signaling: modulation of cancer properies and tumor mircroenvironmentReversible Human TGF-β Signal Shifting between Tumor Suppression and Fibro-Carcinogenesis: Implications of Smad Phospho-Isoforms for Hepatic Epithelial-Mesenchymal TransitionsAberrant regulation of Wnt signaling in hepatocellular carcinomaInference of Network Dynamics and Metabolic Interactions in the Gut MicrobiomeCorrelations in the degeneracy of structurally controllable topologies for networks.Treatment with the herbal formula Songyou Yin inhibits epithelial-mesenchymal transition in hepatocellular carcinoma through downregulation of TGF-β1 expression and inhibition of the SMAD2/3 signaling pathwayEpithelial/mesenchymal plasticity: how have quantitative mathematical models helped improve our understanding?Combinatorial interventions inhibit TGFβ-driven epithelial-to-mesenchymal transition and support hybrid cellular phenotypes.Stability of the hybrid epithelial/mesenchymal phenotype.miR-185-3p regulates nasopharyngeal carcinoma radioresistance by targeting WNT2B in vitro.Cell fate reprogramming by control of intracellular network dynamics.TGFβ signalling pathway regulates angiogenesis by endothelial cells, in an adipose-derived stromal cell/endothelial cell co-culture 3D gel model.Mathematical Modelling of Molecular Pathways Enabling Tumour Cell Invasion and Migration.OVOL guides the epithelial-hybrid-mesenchymal transition.Analysis of a dynamic model of guard cell signaling reveals the stability of signal propagationControl of Stochastic and Induced Switching in Biophysical NetworksInvestigating the mechanism of hepatocellular carcinoma progression by constructing genetic and epigenetic networks using NGS data identification and big database mining methodPopulation Heterogeneity in the Epithelial to Mesenchymal Transition Is Controlled by NFAT and Phosphorylated Sp1.Gene regulatory network underlying the immortalization of epithelial cells.Interrogating the topological robustness of gene regulatory circuits by randomization.Quantitative evaluation and reversion analysis of the attractor landscapes of an intracellular regulatory network for colorectal cancer.Topological constraints on network control profiles.Coupling the modules of EMT and stemness: A tunable 'stemness window' modelMiR-195 is a key negative regulator of hepatocellular carcinoma metastasis by targeting FGF2 and VEGFA.Depletion of histone demethylase KDM5B inhibits cell proliferation of hepatocellular carcinoma by regulation of cell cycle checkpoint proteins p15 and p27.Notch-Jagged signalling can give rise to clusters of cells exhibiting a hybrid epithelial/mesenchymal phenotype.De novo HAPLN1 expression hallmarks Wnt-induced stem cell and fibrogenic networks leading to aggressive human hepatocellular carcinomas.Systems Approaches to Cancer BiologyApigenin inhibits NF-κB and snail signaling, EMT and metastasis in human hepatocellular carcinoma.Hhip regulates tumor-stroma-mediated upregulation of tumor angiogenesis.Systems Perturbation Analysis of a Large-Scale Signal Transduction Model Reveals Potentially Influential Candidates for Cancer Therapeutics.Deciphering Epithelial-Mesenchymal Transition Regulatory Networks in Cancer through Computational ApproachesMetastamiRs: A promising choice for antihepatocellular carcinoma nucleic acid drug development.The evolving concept of liver cancer stem cells.Compensatory interactions to stabilize multiple steady states or mitigate the effects of multiple deregulations in biological networks.Induction of autophagy and apoptosis by miR-148a through the sonic hedgehog signaling pathway in hepatic stellate cells.Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures.Complex Determinants of Epithelial: Mesenchymal Phenotypic Plasticity in Ovarian Cancer.
P2860
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P2860
Network modeling of TGFβ signaling in hepatocellular carcinoma epithelial-to-mesenchymal transition reveals joint sonic hedgehog and Wnt pathway activation
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Network modeling of TGFβ signa ...... hog and Wnt pathway activation
@ast
Network modeling of TGFβ signa ...... hog and Wnt pathway activation
@en
type
label
Network modeling of TGFβ signa ...... hog and Wnt pathway activation
@ast
Network modeling of TGFβ signa ...... hog and Wnt pathway activation
@en
prefLabel
Network modeling of TGFβ signa ...... hog and Wnt pathway activation
@ast
Network modeling of TGFβ signa ...... hog and Wnt pathway activation
@en
P2093
P2860
P1433
P1476
Network modeling of TGFβ signa ...... hog and Wnt pathway activation
@en
P2093
Carl Bart Rountree
David J Feith
Jorge G T Zañudo
Reka Albert
Thomas P Loughran
P2860
P304
P356
10.1158/0008-5472.CAN-14-0225
P407
P577
2014-09-04T00:00:00Z