GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
about
Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death.NLRP3 inflammasome activation in murine macrophages caused by Neospora caninum infection.ATP-Induced Inflammasome Activation and Pyroptosis Is Regulated by AMP-Activated Protein Kinase in Macrophages.Differential roles of caspase-1 and caspase-11 in infection and inflammation.'Hints' in the killer protein gasdermin D: unveiling the secrets of gasdermins driving cell death.A Plant-Derived Nucleic Acid Reconciles Type I IFN and a Pyroptotic-like Event in Immunity against Respiratory Viruses.Enterovirus 71 Inhibits Pyroptosis through Cleavage of Gasdermin D.Melatonin alleviates inflammasome-induced pyroptosis through inhibiting NF-κB/GSDMD signal in mice adipose tissue.Alternative inflammasome activation enables IL-1β release from living cells.Role of the inflammasome in acetaminophen-induced liver injury and acute liver failure.Noncanonical inflammasomes: Antimicrobial defense that does not play by the rules.Programmed cell death as a defence against infection.Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases.Dying to protect: cell death and the control of T-cell homeostasis.Mechanisms governing inflammasome activation, assembly and pyroptosis induction.Gasdermins: Effectors of Pyroptosis.The Role of Interferons in Inflammation and Inflammasome Activation.Inflammasome and autophagy regulation - a two-way street.Immunology: Gut sensor halts viral attack.How inflammasomes inform adaptive immunity.Epithelial Cell Inflammasomes in Intestinal Immunity and Inflammation.The gasdermin-D pore: Executor of pyroptotic cell death.Pore formation by GSDMD is the effector mechanism of pyroptosis.The AIM2 inflammasome: Sensor of pathogens and cellular perturbations.Structure insight of GSDMD reveals the basis of GSDMD autoinhibition in cell pyroptosis.Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin.Baicalin Inhibits NOD-Like Receptor Family, Pyrin Containing Domain 3 Inflammasome Activation in Murine Macrophages by Augmenting Protein Kinase A Signaling.The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity.The Gasdermin-D pore acts as a conduit for IL-1β secretion in mice.Function and regulation of IL-1α in inflammatory diseases and cancer.The intra- and extracellular functions of ASC specks.Inflammasome activation and assembly at a glance.The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages.Inflammatory Caspases: Activation and Cleavage of Gasdermin-D In Vitro and During Pyroptosis.Microparticulate Caspase-1 Regulates Gasdermin-D and Pulmonary Vascular Endothelial Cell Injury.COPs and POPs Patrol Inflammasome Activation.Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury.How ICE lights the pyroptosis fire.Evidence for the activation of pyroptotic and apoptotic pathways in RPE cells associated with NLRP3 inflammasome in the rodent eye.Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
P2860
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P2860
GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
description
2016 nî lūn-bûn
@nan
2016 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
@ast
GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
@en
type
label
GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
@ast
GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
@en
prefLabel
GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
@ast
GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
@en
P2093
P2860
P50
P356
P1433
P1476
GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
@en
P2093
Christopher J Farady
Joka Pipercevic
Lorenzo Sborgi
Rosalie Heilig
Sebastian Rühl
P2860
P304
P356
10.15252/EMBJ.201694696
P407
P577
2016-07-14T00:00:00Z