Variations in the hemagglutinin of the 2009 H1N1 pandemic virus: potential for strains with altered virulence phenotype?
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Acute respiratory distress syndrome induced by a swine 2009 H1N1 variant in miceProgesterone-Based Therapy Protects Against Influenza by Promoting Lung Repair and Recovery in FemalesIdentification of critical residues in the hemagglutinin and neuraminidase of influenza virus H1N1pdm for vaccine virus replication in embryonated chicken eggsTwo years after pandemic influenza A/2009/H1N1: what have we learned?A Role for Neutrophils in Viral Respiratory Disease.Increased virulence of neuraminidase inhibitor-resistant pandemic H1N1 virus in mice: potential emergence of drug-resistant and virulent variantsEvolution of the hemagglutinin protein of the new pandemic H1N1 influenza virus: maintaining optimal receptor binding by compensatory substitutions.Comparative analysis of antibody induction and protection against influenza virus infection by DNA immunization with HA, HAe, and HA1 in mice.Naturally occurring mutations in the PA gene are key contributors to increased virulence of pandemic H1N1/09 influenza virus in mice.Infection and pathogenesis of canine, equine, and human influenza viruses in canine tracheasAll-in-one bacmids: an efficient reverse genetics strategy for influenza A virus vaccines.Hemagglutinin 222D/G polymorphism facilitates fast intra-host evolution of pandemic (H1N1) 2009 influenza A viruses.Analysis of the Contrasting Pathogenicities Induced by the D222G Mutation in 1918 and 2009 Pandemic Influenza A VirusesDifferential Susceptibilities of Human Lung Primary Cells to H1N1 Influenza VirusesReduction of Neuraminidase Activity Exacerbates Disease in 2009 Pandemic Influenza Virus-Infected Mice.Modifications in the polymerase genes of a swine-like triple-reassortant influenza virus to generate live attenuated vaccines against 2009 pandemic H1N1 viruses.Mutations in PA, NP, and HA of a pandemic (H1N1) 2009 influenza virus contribute to its adaptation to miceThe viral nucleoprotein determines Mx sensitivity of influenza A viruses.A novel monoclonal antibody effective against lethal challenge with swine-lineage and 2009 pandemic H1N1 influenza viruses in mice.Cold-adapted influenza and recombinant adenovirus vaccines induce cross-protective immunity against pH1N1 challenge in mice.Putative amino acid determinants of the emergence of the 2009 influenza A (H1N1) virus in the human population.Emerged HA and NA mutants of the pandemic influenza H1N1 viruses with increasing epidemiological significance in Taipei and Kaohsiung, Taiwan, 2009-10.Restored PB1-F2 in the 2009 pandemic H1N1 influenza virus has minimal effects in swine.Mutations in polymerase genes enhanced the virulence of 2009 pandemic H1N1 influenza virus in miceDecreased serologic response in vaccinated military recruits during 2011 correspond to genetic drift in concurrent circulating pandemic A/H1N1 viruses.Implication of inflammatory macrophages, nuclear receptors, and interferon regulatory factors in increased virulence of pandemic 2009 H1N1 influenza A virus after host adaptation.Antibody pressure by a human monoclonal antibody targeting the 2009 pandemic H1N1 virus hemagglutinin drives the emergence of a virus with increased virulence in mice.Heterogeneous virulence of pandemic 2009 influenza H1N1 virus in miceBoth influenza hemagglutinin and polymerase acidic genes are important for delayed pandemic 2009 H1N1 virus clearance in the ferret model.Comparable fitness and transmissibility between oseltamivir-resistant pandemic 2009 and seasonal H1N1 influenza viruses with the H275Y neuraminidase mutation.Corticosteroid treatment ameliorates acute lung injury induced by 2009 swine origin influenza A (H1N1) virus in mice.Neutralizing and protective epitopes of the 2009 pandemic influenza H1N1 hemagglutinin.Receptor characterization and susceptibility of cotton rats to avian and 2009 pandemic influenza virus strainsCharacterization in vitro and in vivo of a pandemic H1N1 influenza virus from a fatal case.The controversy over H5N1 transmissibility research: an opportunity to define a practical response to a global threatPhenotypic differences in virulence and immune response in closely related clinical isolates of influenza A 2009 H1N1 pandemic viruses in mice.Genetic diversity among pandemic 2009 influenza viruses isolated from a transmission chainAdaptation of avian influenza A virus polymerase in mammals to overcome the host species barrierGenomic and protein structural maps of adaptive evolution of human influenza A virus to increased virulence in the mouse.Genome rearrangement of influenza virus for anti-viral drug screening
P2860
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P2860
Variations in the hemagglutinin of the 2009 H1N1 pandemic virus: potential for strains with altered virulence phenotype?
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Variations in the hemagglutini ...... h altered virulence phenotype?
@ast
Variations in the hemagglutini ...... h altered virulence phenotype?
@en
type
label
Variations in the hemagglutini ...... h altered virulence phenotype?
@ast
Variations in the hemagglutini ...... h altered virulence phenotype?
@en
prefLabel
Variations in the hemagglutini ...... h altered virulence phenotype?
@ast
Variations in the hemagglutini ...... h altered virulence phenotype?
@en
P2093
P2860
P50
P1433
P1476
Variations in the hemagglutini ...... h altered virulence phenotype?
@en
P2093
Danielle Hickman
Erin M Sorrell
Haichen Song
Hongxia Shao
Jianqiang Ye
Lindomar Pena
Matthew Angel
P2860
P304
P356
10.1371/JOURNAL.PPAT.1001145
P577
2010-10-14T00:00:00Z