Sphingosine kinase type 1 inhibition reveals rapid turnover of circulating sphingosine 1-phosphate.
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Sphingolipids: a potential molecular approach to treat allergic inflammationSphingosine 1-phosphate induces filopodia formation through S1PR2 activation of ERM proteinsThe emerging role of FTY720 (Fingolimod) in cancer treatmentEvolving concepts in cancer therapy through targeting sphingolipid metabolismRevisiting the sphingolipid rheostat: Evolving concepts in cancer therapySphingosine Kinase 2 Deficiency Attenuates Kidney Fibrosis via IFN-γ.Sphingosine kinase inhibitors: a review of patent literature (2006-2015).Sphingosine Kinase 2 Inhibition and Blood Sphingosine 1-Phosphate Levels.Drugging sphingosine kinases.A metabolic shift favoring sphingosine 1-phosphate at the expense of ceramide controls glioblastoma angiogenesis.Memo has a novel role in S1P signaling and is [corrected] crucial for vascular development.Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate.Design, synthesis and biological activity of sphingosine kinase 2 selective inhibitors.Re-configuration of sphingolipid metabolism by oncogenic transformation.Vascular and Immunobiology of the Circulatory Sphingosine 1-Phosphate Gradient.Targeting the sphingosine-1-phosphate axis in cancer, inflammation and beyond.Sphingolipid metabolites in inflammatory disease.Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy.A selective ATP-competitive sphingosine kinase inhibitor demonstrates anti-cancer properties.Sources, metabolism, and regulation of circulating sphingosine-1-phosphateIncreased mRNA Levels of Sphingosine Kinases and S1P Lyase and Reduced Levels of S1P Were Observed in Hepatocellular Carcinoma in Association with Poorer Differentiation and Earlier Recurrence.Targeting the sphingosine kinase/sphingosine 1-phosphate pathway in disease: review of sphingosine kinase inhibitors.Epidermal growth factor-induced cellular invasion requires sphingosine-1-phosphate/sphingosine-1-phosphate 2 receptor-mediated ezrin activation.Therapeutic Strategies and Pharmacological Tools Influencing S1P Signaling and Metabolism.Assessing the ligand selectivity of sphingosine kinases using molecular dynamics and MM-PBSA binding free energy calculations.Sphingosine-1-phosphate is involved in the occlusive arteriopathy of pulmonary arterial hypertension.Peretinoin, an acyclic retinoid, inhibits hepatocarcinogenesis by suppressing sphingosine kinase 1 expression in vitro and in vivo.Classification of sphingosine kinase inhibitors using counter propagation artificial neural networks: A systematic route for designing selective SphK inhibitors.Increasing circulating sphingosine-1-phosphate attenuates lung injury during ex vivo lung perfusion.Saccharomyces cerevisiae as a platform for assessing sphingolipid lipid kinase inhibitors.
P2860
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P2860
Sphingosine kinase type 1 inhibition reveals rapid turnover of circulating sphingosine 1-phosphate.
description
2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Sphingosine kinase type 1 inhi ...... ating sphingosine 1-phosphate.
@ast
Sphingosine kinase type 1 inhi ...... ating sphingosine 1-phosphate.
@en
type
label
Sphingosine kinase type 1 inhi ...... ating sphingosine 1-phosphate.
@ast
Sphingosine kinase type 1 inhi ...... ating sphingosine 1-phosphate.
@en
prefLabel
Sphingosine kinase type 1 inhi ...... ating sphingosine 1-phosphate.
@ast
Sphingosine kinase type 1 inhi ...... ating sphingosine 1-phosphate.
@en
P2093
P2860
P356
P1433
P1476
Sphingosine kinase type 1 inhi ...... ating sphingosine 1-phosphate.
@en
P2093
Amanda M Gellett
Jose L Tomsig
Kevin R Lynch
Morgan L Moyer
Perry C Kennedy
Thomas P Mathews
Timothy L Macdonald
Yugesh Kharel
P2860
P304
P356
10.1042/BJ20110817
P407
P577
2011-12-01T00:00:00Z