The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella.
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A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and SmoothenedBardet-Biedl syndrome proteins 1 and 3 regulate the ciliary trafficking of polycystic kidney disease 1 proteinBBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypesTULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary ciliaBardet-Biedl syndrome-associated small GTPase ARL6 (BBS3) functions at or near the ciliary gate and modulates Wnt signalingDisruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and miceThe intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.The novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zoneThe conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to ciliaNovel transglutaminase-like peptidase and C2 domains elucidate the structure, biogenesis and evolution of the ciliary compartmentIns and outs of GPCR signaling in primary ciliaSmelling the roses and seeing the light: gene therapy for ciliopathiesThe awesome power of dikaryons for studying flagella and basal bodies in Chlamydomonas reinhardtiiHow do cilia organize signalling cascades?Update on the genetics of bardet-biedl syndromeSingle-particle imaging reveals intraflagellar transport-independent transport and accumulation of EB1 in Chlamydomonas flagella.Conserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary SignalingIFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment.Assembly of IFT trains at the ciliary base depends on IFT74Active transport and diffusion barriers restrict Joubert Syndrome-associated ARL13B/ARL-13 to an Inv-like ciliary membrane subdomainA role for the membrane in regulating Chlamydomonas flagellar length.Trafficking to the ciliary membrane: how to get across the periciliary diffusion barrier?A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition.Architecture and function of IFT complex proteins in ciliogenesisThe BBSome controls IFT assembly and turnaround in cilia.Intraflagellar transport complex structure and cargo interactions.CP110 and its network of partners coordinately regulate cilia assembly.Transition fibre protein FBF1 is required for the ciliary entry of assembled intraflagellar transport complexesThe roles of evolutionarily conserved functional modules in cilia-related trafficking.Cilium assembly and disassemblyIFT-Cargo Interactions and Protein Transport in CiliaNephrocystin proteins NPHP5 and Cep290 regulate BBSome integrity, ciliary trafficking and cargo deliveryRSK phosphorylates SOS1 creating 14-3-3-docking sites and negatively regulating MAPK activationIFT27, encoding a small GTPase component of IFT particles, is mutated in a consanguineous family with Bardet-Biedl syndromeLeptin resistance is a secondary consequence of the obesity in ciliopathy mutant miceFunctional characterization of putative cilia genes by high-content analysisGene therapy prevents photoreceptor death and preserves retinal function in a Bardet-Biedl syndrome mouse model.Distinct functions for IFT140 and IFT20 in opsin transportLoss of Bardet-Biedl syndrome protein-8 (BBS8) perturbs olfactory function, protein localization, and axon targetingIFT20 is required for opsin trafficking and photoreceptor outer segment development
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P2860
The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella.
description
2009 nî lūn-bûn
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2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
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2009年论文
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name
The Chlamydomonas reinhardtii ...... naling proteins from flagella.
@ast
The Chlamydomonas reinhardtii ...... naling proteins from flagella.
@en
type
label
The Chlamydomonas reinhardtii ...... naling proteins from flagella.
@ast
The Chlamydomonas reinhardtii ...... naling proteins from flagella.
@en
prefLabel
The Chlamydomonas reinhardtii ...... naling proteins from flagella.
@ast
The Chlamydomonas reinhardtii ...... naling proteins from flagella.
@en
P2093
P2860
P356
P1476
The Chlamydomonas reinhardtii ...... naling proteins from flagella.
@en
P2093
Bryan A Ballif
Deborah Cochran
Eric C Johnson
George B Witman
Karl-Ferdinand Lechtreck
Mitsuo Ikebe
Tsuyoshi Sakai
P2860
P304
P356
10.1083/JCB.200909183
P407
P577
2009-12-01T00:00:00Z