Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice. - Test2 - elhamkhani - TriplyDB

Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice.

Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice.

http://www.wikidata.org/entity/Q30438279

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Stabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeability Chemokine receptors and their therapeutic opportunities in diseased lung: far beyond leukocyte trafficking CXCR2: a target for pancreatic cancer treatment?Genetic Ablation of CXCR2 Protects against Cigarette Smoke-Induced Lung Inflammation and Injury Eliminating or blocking 12/15-lipoxygenase reduces neutrophil recruitment in mouse models of acute lung injury In vivo two-photon imaging reveals monocyte-dependent neutrophil extravasation during pulmonary inflammation.Importance of CXC chemokine receptor 2 in alveolar neutrophil and exudate macrophage recruitment in response to pneumococcal lung infection.Defective regulation of CXCR2 facilitates neutrophil release from bone marrow causing spontaneous inflammation in severely NF-kappa B-deficient mice.Hematopoietic Pyk2 regulates migration of differentiated HL-60 cells.A role for Rab27 in neutrophil chemotaxis and lung recruitment.Reduced pulmonary blood flow in regions of injury 2 hours after acid aspiration in rats.Computational Advances for the Development of Allosteric Modulators and Bitopic Ligands in G Protein-Coupled Receptors Milk fat globule-epidermal growth factor-factor 8 attenuates neutrophil infiltration in acute lung injury via modulation of CXCR2.Neutrophils are required for 3-methylcholanthrene-initiated, butylated hydroxytoluene-promoted lung carcinogenesis.Management of hypersensivity pneumonitis Endothelial bioreactor system ameliorates multiple organ dysfunction in septic rats.Genetic and Pharmacologic Inhibition of the Chemokine Receptor CXCR2 Prevents Experimental Hypertension and Vascular Dysfunction.International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors.The functional significance behind expressing two IL-8 receptor types on PMN.Pulmonary macrophage subpopulations in the induction and resolution of acute lung injury.Opening the flood-gates: how neutrophil-endothelial interactions regulate permeability.Role of the pulmonary epithelium and inflammatory signals in acute lung injury.Contribution of neutrophils to acute lung injury CXCR2 in acute lung injury.CXCR2: From Bench to Bedside.Growth factors and cytokines in acute lung injury.The mercurial nature of neutrophils: still an enigma in ARDS?Blockade of CXCR2 signalling: a potential therapeutic target for preventing neutrophil-mediated inflammatory diseases.Allosteric and biased g protein-coupled receptor signaling regulation: potentials for new therapeutics.Role of the CXCL8-CXCR1/2 Axis in Cancer and Inflammatory Diseases.Continuous venovenous hemofiltration decreases mortality and ameliorates acute lung injury in canine model of severe salt water drowning.IL33-mediated ILC2 activation and neutrophil IL5 production in the lung response after severe trauma: A reverse translation study from a human cohort to a mouse trauma model.Donor pulmonary intravascular nonclassical monocytes recruit recipient neutrophils and mediate primary lung allograft dysfunction.Maxadilan, the Lutzomyia longipalpis vasodilator, drives plasma leakage via PAC1-CXCR1/2-pathway.A pilot study on reparixin, a CXCR1/2 antagonist, to assess safety and efficacy in attenuating ischaemia-reperfusion injury and inflammation after on-pump coronary artery bypass graft surgery.Biocompatible polymeric nanoparticles degrade and release cargo in response to biologically relevant levels of hydrogen peroxide.Induced pluripotent stem cells reduce neutrophil chemotaxis via activating GRK2 in endotoxin-induced acute lung injury.Platelet-Specific Chemokines Contribute to the Pathogenesis of Acute Lung Injury.Chemokine receptors in a regulation of interstitial lung fibrosis and inflammation.Therapeutic inhibition of CXC chemokine receptor 2 by SB225002 attenuates LPS-induced acute lung injury in mice.

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P2860

Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice.

http://www.wikidata.org/entity/Q30438279

description

2008 nî lūn-bûn

@nan

2008 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հունիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice.

@ast

Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice.

@en

type

label

Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice.

@ast

Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice.

@en

prefLabel

Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice.

@ast

Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice.

@en

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British Journal of Pharmacology

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Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice.

@en

P2093

A Zarbock

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K Ley

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M Allegretti

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P2860

P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

Inhibition of interleukin-8 (CXCL8/IL-8) responses by repertaxin, a new inhibitor of the chemokine receptors CXCR1 and CXCR2

The acute respiratory distress syndrome

Chemokines and chemokine receptors in leukocyte trafficking.

Sequential recruitment of neutrophils into lung and bronchoalveolar lavage fluid in LPS-induced acute lung injury.

The role of platelets in acute lung injury (ALI)

Critical role of endothelial CXCR2 in LPS-induced neutrophil migration into the lung.

Spleen tyrosine kinase Syk is necessary for E-selectin-induced alpha(L)beta(2) integrin-mediated rolling on intercellular adhesion molecule-1.

Galphai2 is required for chemokine-induced neutrophil arrest.

Blocking p21-activated kinase reduces lipopolysaccharide-induced acute lung injury by preventing polymorphonuclear leukocyte infiltration.

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357-364

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10.1038/BJP.2008.270

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3

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155

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2008-06-30T00:00:00Z

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5267365

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18587419

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2567887

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