P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac
about
Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles ...P-Rex2, a new guanine-nucleotide exchange factor for RacHem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxisThe Rho-family GEF Asef2 activates Rac to modulate adhesion and actin dynamics and thereby regulate cell migrationPLEKHG2 promotes heterotrimeric G protein βγ-stimulated lymphocyte migration via Rac and Cdc42 activation and actin polymerization.Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2aParallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxisInternational Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) familyDOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxisThe Novel Functions of the PLC/PKC/PKD Signaling Axis in G Protein-Coupled Receptor-Mediated Chemotaxis of NeutrophilsMoving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytesS1PR2 links germinal center confinement and growth regulationRho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and diseaseNADPH oxidases in heart failure: poachers or gamekeepers?Phosphoinositides: tiny lipids with giant impact on cell regulationSubcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disordersp21-Activated kinase (PAK) regulates cytoskeletal reorganization and directional migration in human neutrophilsNorbin Stimulates the Catalytic Activity and Plasma Membrane Localization of the Guanine-Nucleotide Exchange Factor P-Rex1.Regulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulationSynaptic P-Rex1 signaling regulates hippocampal long-term depression and autism-like social behaviorP-Rex1 cooperates with PDGFRβ to drive cellular migration in 3D microenvironmentsPI3Kδ promotes CD4(+) T-cell interactions with antigen-presenting cells by increasing LFA-1 binding to ICAM-1.How cells integrate complex stimuli: the effect of feedback from phosphoinositides and cell shape on cell polarization and motilityStructure of Galphaq-p63RhoGEF-RhoA complex reveals a pathway for the activation of RhoA by GPCRsThe Minimal Autoinhibited Unit of the Guanine Nucleotide Exchange Factor IntersectinRegulation and function of P-Rex family Rac-GEFsLL5beta is a phosphatidylinositol (3,4,5)-trisphosphate sensor that can bind the cytoskeletal adaptor, gamma-filaminThe C-terminal basic tail of RhoG assists the guanine nucleotide exchange factor trio in binding to phospholipidsSignaling by the phosphoinositide 3-kinase family in immune cellsActivation and assembly of the NADPH oxidase: a structural perspectiveLoss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targetingAlsin is a Rab5 and Rac1 guanine nucleotide exchange factorP-Rex2 regulates Purkinje cell dendrite morphology and motor coordination.Vav GEFs are required for beta2 integrin-dependent functions of neutrophils.Regulation of immature dendritic cell migration by RhoA guanine nucleotide exchange factor Arhgef5Multifunctional roles for the PH domain of Dbs in regulating Rho GTPase activationThe Src family kinases Hck and Fgr regulate neutrophil responses to N-formyl-methionyl-leucyl-phenylalanineSignaling networks that regulate cell migrationDifferential sensitivity of phosphatidylinositol 3-kinase p110gamma to isoforms of G protein betagamma dimers.Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice.
P2860
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P2860
P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac
description
2002 nî lūn-bûn
@nan
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
P-Rex1, a PtdIns(3,4,5)P3- and ...... eotide exchange factor for Rac
@ast
P-Rex1, a PtdIns(3,4,5)P3- and ...... eotide exchange factor for Rac
@en
P-Rex1, a PtdIns(3,4,5)P3- and ...... eotide exchange factor for Rac
@en-gb
P-Rex1, a PtdIns(3,4,5)P3- and ...... eotide exchange factor for Rac
@nl
type
label
P-Rex1, a PtdIns(3,4,5)P3- and ...... eotide exchange factor for Rac
@ast
P-Rex1, a PtdIns(3,4,5)P3- and ...... eotide exchange factor for Rac
@en
P-Rex1, a PtdIns(3,4,5)P3- and ...... eotide exchange factor for Rac
@en-gb
P-Rex1, a PtdIns(3,4,5)P3- and ...... eotide exchange factor for Rac
@nl
prefLabel
P-Rex1, a PtdIns(3,4,5)P3- and ...... eotide exchange factor for Rac
@ast
P-Rex1, a PtdIns(3,4,5)P3- and ...... eotide exchange factor for Rac
@en
P-Rex1, a PtdIns(3,4,5)P3- and ...... eotide exchange factor for Rac
@en-gb
P-Rex1, a PtdIns(3,4,5)P3- and ...... eotide exchange factor for Rac
@nl
P2093
P50
P3181
P1433
P1476
P-Rex1, a PtdIns(3,4,5)P3- and ...... eotide exchange factor for Rac
@en
P2093
Christian D Ellson
G John Ferguson
Simon R Andrews
W John Coadwell
P304
P3181
P356
10.1016/S0092-8674(02)00663-3
P407
P577
2002-03-22T00:00:00Z