Impaired social interactions and motor learning skills in tuberous sclerosis complex model mice expressing a dominant/negative form of tuberin - Test2 - elhamkhani - TriplyDB

Impaired social interactions and motor learning skills in tuberous sclerosis complex model mice expressing a dominant/negative form of tuberin

Impaired social interactions and motor learning skills in tuberous sclerosis complex model mice expressing a dominant/negative form of tuberin

http://www.wikidata.org/entity/Q30459608

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Clinical and Neurobiological Relevance of Current Animal Models of Autism Spectrum Disorders.Behavioral phenotypes of genetic mouse models of autism.Dendritic spine dysgenesis in autism related disorders Seizure-dependent mTOR activation in 5-HT neurons promotes autism-like behaviors in mice Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits The BTBR T+ tf/J mouse model for autism spectrum disorders-in search of biomarkers.Manual versus Automated Rodent Behavioral Assessment: Comparing Efficacy and Ease of Bederson and Garcia Neurological Deficit Scores to an Open Field Video-Tracking System.Selective suppression of excessive GluN2C expression rescues early epilepsy in a tuberous sclerosis murine model.A circuitry and biochemical basis for tuberous sclerosis symptoms: from epilepsy to neurocognitive deficits Mechanism-based treatment in tuberous sclerosis complex.The interaction between early life epilepsy and autistic-like behavioral consequences: a role for the mammalian target of rapamycin (mTOR) pathway.Exaggerated translation causes synaptic and behavioural aberrations associated with autism.Increasing our understanding of human cognition through the study of Fragile X Syndrome.Genetic activation of mTORC1 signaling worsens neurocognitive outcome after traumatic brain injury.Metabotropic glutamate receptor-dependent long-term depression is impaired due to elevated ERK signaling in the ΔRG mouse model of tuberous sclerosis complex.Synaptic plasticity in mouse models of autism spectrum disorders.Ethanol and Caffeine Effects on Social Interaction and Recognition in Mice: Involvement of Adenosine A2A and A1 Receptors.Synaptic plasticity and learning in animal models of tuberous sclerosis complex.Dysregulated mTORC1-Dependent Translational Control: From Brain Disorders to Psychoactive Drugs.Tsc1 haploinsufficiency is sufficient to increase dendritic patterning and Filamin A levels.Conditional and domain-specific inactivation of the Tsc2 gene in neural progenitor cells.Tuber-Less Models of Tuberous Sclerosis Still Provide Insights Into Epilepsy.

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P2860

Impaired social interactions and motor learning skills in tuberous sclerosis complex model mice expressing a dominant/negative form of tuberin

http://www.wikidata.org/entity/Q30459608

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2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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J.NBD.2011.07.018

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Neurobiology of Disease

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Impaired social interactions a ...... inant/negative form of tuberin

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Emanuela Santini

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Eric Klann

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Jordan M Maki

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P2860

Characterization of the cytosolic tuberin-hamartin complex. Tuberin is a cytosolic chaperone for hamartin

Mutational analysis in a cohort of 224 tuberous sclerosis patients indicates increased severity of TSC2, compared with TSC1, disease in multiple organs

Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety

The tuberous sclerosis complex

mTOR signaling: at the crossroads of plasticity, memory and disease

Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis

Gabrb3 gene deficient mice exhibit impaired social and exploratory behaviors, deficits in non-selective attention and hypoplasia of cerebellar vermal lobules: a potential model of autism spectrum disorder

Neuroligin-1 deletion results in impaired spatial memory and increased repetitive behavior.

Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16

Molecular genetic and phenotypic analysis reveals differences between TSC1 and TSC2 associated familial and sporadic tuberous sclerosis

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156-164

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10.1016/J.NBD.2011.07.018

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1

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45

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Itzamarie Chévere-Torres

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2011-07-30T00:00:00Z

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51558182

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3225564

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