Neuroligin-1 deletion results in impaired spatial memory and increased repetitive behavior.
about
Gephyrin, the enigmatic organizer at GABAergic synapsesGenetic-background modulation of core and variable autistic-like symptoms in Fmr1 knock-out mice.Neuroligin-1-dependent competition regulates cortical synaptogenesis and synapse numberAutistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor functionShank3 mutant mice display autistic-like behaviours and striatal dysfunctionEmerging pharmacotherapies for neurodevelopmental disordersGABAB-mediated rescue of altered excitatory-inhibitory balance, gamma synchrony and behavioral deficits following constitutive NMDAR-hypofunction.Neurexins and neuroligins: recent insights from invertebratesThe structure of neurexin 1α reveals features promoting a role as synaptic organizerLeucine-rich repeat transmembrane proteins are essential for maintenance of long-term potentiationRegion-specific deletions of RIM1 reproduce a subset of global RIM1α(-/-) phenotypesAutism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic functionSynCAM 1 adhesion dynamically regulates synapse number and impacts plasticity and learning.Clinical and Neurobiological Relevance of Current Animal Models of Autism Spectrum Disorders.Mouse Genetic Models of Human Brain DisordersPrefrontal Cortex and Social Cognition in Mouse and ManBehavioral phenotypes of genetic mouse models of autism.Genes, circuits, and precision therapies for autism and related neurodevelopmental disordersFollowing the genes: a framework for animal modeling of psychiatric disordersThe molecular basis of cognitive deficits in pervasive developmental disordersThe role of glutamate and its receptors in autism and the use of glutamate receptor antagonists in treatment.Brain-specific transcriptional regulator T-brain-1 controls brain wiring and neuronal activity in autism spectrum disordersCell biology in neuroscience: the interplay between Hebbian and homeostatic synaptic plasticityNMDA receptor agonists reverse impaired psychomotor and cognitive functions associated with hippocampal Hbegf-deficiency in miceHippocampal neuroligin-2 overexpression leads to reduced aggression and inhibited novelty reactivity in ratsOverexpression of Homer1a in the basal and lateral amygdala impairs fear conditioning and induces an autism-like social impairmentNeuroligin-1 loss is associated with reduced tenacity of excitatory synapsesHeterozygous deletion of α-neurexin I or α-neurexin II results in behaviors relevant to autism and schizophrenia.Advancing the understanding of autism disease mechanisms through geneticsSynaptopathies: synaptic dysfunction in neurological disorders - A review from students to studentsThe interplay between synaptic activity and neuroligin function in the CNSCommon mechanisms of excitatory and inhibitory imbalance in schizophrenia and autism spectrum disordersDeletion of α-neurexin II results in autism-related behaviors in miceThe postsynaptic adenomatous polyposis coli (APC) multiprotein complex is required for localizing neuroligin and neurexin to neuronal nicotinic synapses in vivoTranslational Mouse Models of Autism: Advancing Toward Pharmacological Therapeutics.LRRTM1-deficient mice show a rare phenotype of avoiding small enclosures--a tentative mouse model for claustrophobia-like behaviour.Neuroligin-1 links neuronal activity to sleep-wake regulationTSHZ3 deletion causes an autism syndrome and defects in cortical projection neurons.A subtype-specific function for the extracellular domain of neuroligin 1 in hippocampal LTPEpigenetic suppression of neuroligin 1 underlies amyloid-induced memory deficiency
P2860
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P2860
Neuroligin-1 deletion results in impaired spatial memory and increased repetitive behavior.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Neuroligin-1 deletion results ...... increased repetitive behavior
@nl
Neuroligin-1 deletion results ...... increased repetitive behavior.
@ast
Neuroligin-1 deletion results ...... increased repetitive behavior.
@en
type
label
Neuroligin-1 deletion results ...... increased repetitive behavior
@nl
Neuroligin-1 deletion results ...... increased repetitive behavior.
@ast
Neuroligin-1 deletion results ...... increased repetitive behavior.
@en
prefLabel
Neuroligin-1 deletion results ...... increased repetitive behavior
@nl
Neuroligin-1 deletion results ...... increased repetitive behavior.
@ast
Neuroligin-1 deletion results ...... increased repetitive behavior.
@en
P2093
P2860
P3181
P1476
Neuroligin-1 deletion results ...... increased repetitive behavior.
@en
P2093
Christopher Walz
Cory A Blaiss
Felipe Espinosa
Jacqueline Blundell
Katsuhiko Tabuchi
Marc F Bolliger
Mark R Etherton
P2860
P304
P3181
P356
10.1523/JNEUROSCI.4517-09.2010
P407
P577
2010-02-01T00:00:00Z