Cell cycle progression and chromosome segregation in mammalian cells cultured in the presence of the topoisomerase II inhibitors ICRF-187 [(+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane; ADR-529] and ICRF-159 (Razoxane).
about
Construction, characterization, and complementation of a conditional-lethal DNA topoisomerase IIalpha mutant human cell lineHow to be a mitotic chromosomeDual role of topoisomerase II in centromere resolution and aurora B activityEssential roles of Drosophila inner centromere protein (INCENP) and aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregationInhibition of human topoisomerase II in vitro by bioactive benzene metabolitesRapid exchange of mammalian topoisomerase II alpha at kinetochores and chromosome arms in mitosisMitotic catenation is monitored and resolved by a PKCε-regulated pathwayTopoisomerase II and histone deacetylase inhibitors delay the G2/M transition by triggering the p38 MAPK checkpoint pathwayTopoisomerase IIalpha binding domains of adenomatous polyposis coli influence cell cycle progression and aneuploidy.PICH and cotargeted Plk1 coordinately maintain prometaphase chromosome arm architecture.Forces on chromosomal DNA during anaphase.Canonical non-homologous end joining in mitosis induces genome instability and is suppressed by M-phase-specific phosphorylation of XRCC4Analysis of Scc1-deficient cells defines a key metaphase role of vertebrate cohesin in linking sister kinetochores.PIASy-dependent SUMOylation regulates DNA topoisomerase IIalpha activity.Depletion of topoisomerase IIalpha leads to shortening of the metaphase interkinetochore distance and abnormal persistence of PICH-coated anaphase threads.Chromosome Bridges Maintain Kinetochore-Microtubule Attachment throughout Mitosis and Rarely Break during AnaphaseMerotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cellsThe decatenation checkpoint.Inhibition of chromosomal separation provides insights into cleavage furrow stimulation in cultured epithelial cells.SUMO modification of DNA topoisomerase II: trying to get a CENse of it allThe α isoform of topoisomerase II is required for hypercompaction of mitotic chromosomes in human cells.Mammalian Fbh1 is important to restore normal mitotic progression following decatenation stress.Inhibition of topoisomerase II by ICRF-193 prevents efficient replication of herpes simplex virus type 1.A postprophase topoisomerase II-dependent chromatid core separation step in the formation of metaphase chromosomes.Genome-Scale Genetic Interactions and Cell Imaging Confirm Cytokinesis as Deleterious to Transient Topoisomerase II Deficiency in Saccharomyces cerevisiae.A Topology-Centric View on Mitotic Chromosome Architecture.The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity.
P2860
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P2860
Cell cycle progression and chromosome segregation in mammalian cells cultured in the presence of the topoisomerase II inhibitors ICRF-187 [(+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane; ADR-529] and ICRF-159 (Razoxane).
description
1994 nî lūn-bûn
@nan
1994 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Cell cycle progression and chr ...... -529] and ICRF-159 (Razoxane).
@ast
Cell cycle progression and chr ...... -529] and ICRF-159 (Razoxane).
@en
type
label
Cell cycle progression and chr ...... -529] and ICRF-159 (Razoxane).
@ast
Cell cycle progression and chr ...... -529] and ICRF-159 (Razoxane).
@en
prefLabel
Cell cycle progression and chr ...... -529] and ICRF-159 (Razoxane).
@ast
Cell cycle progression and chr ...... -529] and ICRF-159 (Razoxane).
@en
P1433
P1476
Cell cycle progression and chr ...... R-529] and ICRF-159 (Razoxane)
@en
P2093
Gorbsky GJ
P304
P407
P577
1994-02-01T00:00:00Z