Rapid exchange of mammalian topoisomerase II alpha at kinetochores and chromosome arms in mitosis - Test2 - elhamkhani - TriplyDB

Rapid exchange of mammalian topoisomerase II alpha at kinetochores and chromosome arms in mitosis

Rapid exchange of mammalian topoisomerase II alpha at kinetochores and chromosome arms in mitosis

http://www.wikidata.org/entity/Q30441918

about

Construction, characterization, and complementation of a conditional-lethal DNA topoisomerase IIalpha mutant human cell line Proteomic analysis of human metaphase chromosomes reveals topoisomerase II alpha as an Aurora B substrate.How to be a mitotic chromosome SUMO-2/3 regulates topoisomerase II in mitosis Condensed mitotic chromatin is accessible to transcription factors and chromatin structural proteins SUMOylation in control of accurate chromosome segregation during mitosis PIASgamma is required for faithful chromosome segregation in human cells Direct monitoring of the strand passage reaction of DNA topoisomerase II triggers checkpoint activation Dual role of topoisomerase II in centromere resolution and aurora B activity DDK dependent regulation of TOP2A at centromeres revealed by a chemical genetics approach Analysis of cryo-electron microscopy images does not support the existence of 30-nm chromatin fibers in mitotic chromosomes in situ A novel chromatin tether domain controls topoisomerase IIα dynamics and mitotic chromosome formation.Topoisomerase II and histone deacetylase inhibitors delay the G2/M transition by triggering the p38 MAPK checkpoint pathway Analysis of Scc1-deficient cells defines a key metaphase role of vertebrate cohesin in linking sister kinetochores.The dynamics of DNA topoisomerase IIalpha in living cells PIASy-dependent SUMOylation regulates DNA topoisomerase IIalpha activity.The analysis of mutant alleles of different strength reveals multiple functions of topoisomerase 2 in regulation of Drosophila chromosome structure.Mitotic chromosome scaffold structure: new approaches to an old controversy Visualization of early chromosome condensation: a hierarchical folding, axial glue model of chromosome structure.Depletion of topoisomerase IIalpha leads to shortening of the metaphase interkinetochore distance and abnormal persistence of PICH-coated anaphase threads.Neocentromeres: new insights into centromere structure, disease development, and karyotype evolution Chromosomes Progress to Metaphase in Multiple Discrete Steps via Global Compaction/Expansion Cycles.Stacked thin layers of metaphase chromatin explain the geometry of chromosome rearrangements and banding Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation A role of topoisomerase II in linking DNA replication to chromosome condensation.Imaging the division process in living tissue culture cells.Regulation of the catalytic function of topoisomerase II alpha through association with RNA Packaging the genome: the structure of mitotic chromosomes Nucleolus-like body of mouse oocytes contains lamin A and B and TRF2 but not actin and topo II.SUMO modification of DNA topoisomerase II: trying to get a CENse of it all The SMC complexes, DNA and chromosome topology: right or knot?Shaping mitotic chromosomes: From classical concepts to molecular mechanisms.The α isoform of topoisomerase II is required for hypercompaction of mitotic chromosomes in human cells.Mitosis-specific MPM-2 phosphorylation of DNA topoisomerase IIalpha is regulated directly by protein phosphatase 2A.Characterization of human NSCLC cell line with innate etoposide-resistance mediated by cytoplasmic localization of topoisomerase II alpha.Proteome analysis of human metaphase chromosomes.Human topoisomerase IIalpha: targeting to subchromosomal sites of activity during interphase and mitosis.Mitotic chromosomes are compacted laterally by KIF4 and condensin and axially by topoisomerase IIα Non-Catalytic Roles of the Topoisomerase IIα C-Terminal Domain.The Ins and Outs of Aurora B Inner Centromere Localization.

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Rapid exchange of mammalian topoisomerase II alpha at kinetochores and chromosome arms in mitosis

http://www.wikidata.org/entity/Q30441918

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2002 nî lūn-bûn

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Rapid exchange of mammalian to ...... and chromosome arms in mitosis

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Joanna R Hudson

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Marie-George Côme

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Penny A Tavormina

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William T Beck

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Yin-Yuan Mo

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P2860

Cell cycle-coupled relocation of types I and II topoisomerases and modulation of catalytic enzyme activities

Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events.

High mobility of proteins in the mammalian cell nucleus

DNA topoisomerase II alpha is the major chromosome protein recognized by the mitotic phosphoprotein antibody MPM-2

Microtubules in the metaphase-arrested mouse oocyte turn over rapidly

Cell cycle progression and chromosome segregation in mammalian cells cultured in the presence of the topoisomerase II inhibitors ICRF-187 [(+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane; ADR-529] and ICRF-159 (Razoxane).

Two differentially spliced forms of topoisomerase IIalpha and beta mRNAs are conserved between birds and humans.

Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle.

The nucleolus: an old factory with unexpected capabilities.

Functional and regulatory characteristics of eukaryotic type II DNA topoisomerase.

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1

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158

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Gary J. Gorbsky

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2002-07-08T00:00:00Z

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11272987

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12105179

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2173008

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