Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein.
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Threats to the mind: aging, amyloid, and hypertensionCerebral Small Vessel Disease: Targeting Oxidative Stress as a Novel Therapeutic Strategy?Vascular contributions to cognitive impairment and dementia including Alzheimer's diseaseEvolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target EngagementRedox control of microglial function: molecular mechanisms and functional significanceThe pathobiology of vascular dementiaOxidized cholesterol as the driving force behind the development of Alzheimer's diseaseHypertension: a harbinger of stroke and dementiaAging-related alterations in eNOS and nNOS responsiveness and smooth muscle reactivity of murine basilar arteries are modulated by apocynin and phosphorylation of myosin phosphatase targeting subunit-1Oxidation-Responsive, EuII/III-Based, Multimodal Contrast Agent for Magnetic Resonance and Photoacoustic ImagingLimitations of collateral flow after occlusion of a single cortical penetrating arterioleTriterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease.Water deprivation induces neurovascular and cognitive dysfunction through vasopressin-induced oxidative stressContribution of reactive oxygen species to cerebral amyloid angiopathy, vasomotor dysfunction, and microhemorrhage in aged Tg2576 mice.Cyclooxygenase 1-derived prostaglandin E2 and EP1 receptors are required for the cerebrovascular dysfunction induced by angiotensin II.A palette of fluorescent probes with varying emission colors for imaging hydrogen peroxide signaling in living cellsEstrogen attenuates ischemic oxidative damage via an estrogen receptor alpha-mediated inhibition of NADPH oxidase activationThe cerebrovascular dysfunction induced by slow pressor doses of angiotensin II precedes the development of hypertensionEuropean contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).NOX activity is increased in mild cognitive impairmentTransgenic mice overexpressing amyloid precursor protein exhibit early metabolic deficits and a pathologically low leptin state associated with hypothalamic dysfunction in arcuate neuropeptide Y neuronsVascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association.Role of vascular risk factors and vascular dysfunction in Alzheimer's disease.Vascular and metabolic dysfunction in Alzheimer's disease: a review.Targeting NOX enzymes in the central nervous system: therapeutic opportunities.Endothelin 1-dependent neurovascular dysfunction in chronic intermittent hypoxia.Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimer's diseaseTransgenic mice overexpressing APP and transforming growth factor-beta1 feature cognitive and vascular hallmarks of Alzheimer's diseaseThe overlap between neurodegenerative and vascular factors in the pathogenesis of dementiaProliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner.Brain and circulating levels of Aβ1-40 differentially contribute to vasomotor dysfunction in the mouse brain.Nox2 redox signaling maintains essential cell populations in the brain.Oxidative stress, redox signalling and endothelial dysfunction in ageing-related neurodegenerative diseases: a role of NADPH oxidase 2.Genome-wide alteration of histone H3K9 acetylation pattern in mouse offspring prenatally exposed to arsenicResveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase.The role of the NADPH oxidase NOX2 in prion pathogenesis.Cognitive and cerebrovascular improvements following kinin B1 receptor blockade in Alzheimer's disease mice.Tissue plasminogen activator is required for the development of fetal alcohol syndrome in mice.Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-beta.Juvenile traumatic brain injury induces long-term perivascular matrix changes alongside amyloid-beta accumulation.
P2860
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P2860
Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Nox2-derived radicals contribu ...... the amyloid precursor protein.
@ast
Nox2-derived radicals contribu ...... the amyloid precursor protein.
@en
type
label
Nox2-derived radicals contribu ...... the amyloid precursor protein.
@ast
Nox2-derived radicals contribu ...... the amyloid precursor protein.
@en
prefLabel
Nox2-derived radicals contribu ...... the amyloid precursor protein.
@ast
Nox2-derived radicals contribu ...... the amyloid precursor protein.
@en
P2093
P2860
P356
P1476
Nox2-derived radicals contribu ...... the amyloid precursor protein.
@en
P2093
Bruce S McEwen
Carmen Capone
Erin H Norris
George Carlson
Laibaik Park
Linda Younkin
Rose Pitstick
Steven Younkin
P2860
P304
P356
10.1073/PNAS.0711568105
P407
P577
2008-01-17T00:00:00Z