5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice - Test2 - elhamkhani - TriplyDB

5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice

5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice

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Differential contributions of serotonin receptors to the behavioral effects of indoleamine hallucinogens in mice Head-twitch response in rodents induced by the hallucinogen 2,5-dimethoxy-4-iodoamphetamine: a comprehensive history, a re-evaluation of mechanisms, and its utility as a model.The HIV antiretroviral drug efavirenz has LSD-like properties The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogen Multiple receptors contribute to the behavioral effects of indoleamine hallucinogens.Preclinical models of antipsychotic drug action.Serotonergic modulation of post-synaptic inhibition and locomotor alternating pattern in the spinal cord Recent advances in the neuropsychopharmacology of serotonergic hallucinogens Psychedelics Distinct neural mechanisms underlying acute and repeated administration of antipsychotic drugs in rat avoidance conditioning.Altered exploration and sensorimotor gating of the chakragati mouse model of schizophrenia.Antipurinergic therapy corrects the autism-like features in the Fragile X (Fmr1 knockout) mouse model.Further evidence for ClockΔ19 mice as a model for bipolar disorder mania using cross-species tests of exploration and sensorimotor gating.Delayed procedural learning in α7-nicotinic acetylcholine receptor knockout mice.Animal models of serotonergic psychedelics.Enhanced effects of amphetamine but reduced effects of the hallucinogen, 5-MeO-DMT, on locomotor activity in 5-HT(1A) receptor knockout mice: implications for schizophrenia.Clozapine, but not olanzapine, disrupts conditioned avoidance response in rats by antagonizing 5-HT2A/2C receptors.The effect of reduced dopamine D4 receptor expression in the 5-choice continuous performance task: Separating response inhibition from premature responding.Alpha1,6-fucosyltransferase-deficient mice exhibit multiple behavioral abnormalities associated with a schizophrenia-like phenotype: importance of the balance between the dopamine and serotonin systems.Modeling the positive symptoms of schizophrenia in genetically modified mice: pharmacology and methodology aspects LSD but not lisuride disrupts prepulse inhibition in rats by activating the 5-HT(2A) receptor.mRNA expression profile of serotonin receptor subtypes and distribution of serotonergic terminations in marmoset brain Effects of 5-hydroxytryptamine 2C receptor agonist MK212 and 2A receptor antagonist MDL100907 on maternal behavior in postpartum female rats The mania-like exploratory profile in genetic dopamine transporter mouse models is diminished in a familiar environment and reinstated by subthreshold psychostimulant administration Maternal influenza viral infection causes schizophrenia-like alterations of 5-HT₂A and mGlu₂ receptors in the adult offspring.Interactive effects of mGlu5 and 5-HT2A receptors on locomotor activity in mice Dopamine receptor mediation of the exploratory/hyperactivity effects of modafinil.Selective serotonin 5-HT(2C) receptor activation suppresses the reinforcing efficacy of cocaine and sucrose but differentially affects the incentive-salience value of cocaine- vs. sucrose-associated cues.Effects of hallucinogenic agents mescaline and phencyclidine on zebrafish behavior and physiology.The 5-HT2C receptor agonist lorcaserin reduces nicotine self-administration, discrimination, and reinstatement: relationship to feeding behavior and impulse control Role for serotonin2A (5-HT2A) and 2C (5-HT2C) receptors in experimental absence seizures.Genotype-Dependent Difference in 5-HT2C Receptor-Induced Hypolocomotion: Comparison with 5-HT2A Receptor Functional Activity.Disruption of prefrontal cortex large scale neuronal activity by different classes of psychotomimetic drugs Activation of 5-HT2A receptors upregulates the function of the neuronal K-Cl cotransporter KCC2.Sertraline exposure leads to small left heart syndrome in adult mice.Peptide inhibitors disrupt the serotonin 5-HT2C receptor interaction with phosphatase and tensin homolog to allosterically modulate cellular signaling and behavior.2-Bromoterguride-a potential atypical antipsychotic drug without metabolic effects in rats.Support for 5-HT2C receptor functional selectivity in vivo utilizing structurally diverse, selective 5-HT2C receptor ligands and the 2,5-dimethoxy-4-iodoamphetamine elicited head-twitch response model Hippocampal serotonin depletion unmasks differences in the hyperlocomotor effects of phencyclidine and MK-801: quantitative versus qualitative analyses Neurotoxic Effects of 5-MeO-DIPT: A Psychoactive Tryptamine Derivative in Rats.

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5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice

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2009 nî lūn-bûn

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2009 թուականի Մարտին հրատարակուած գիտական յօդուած

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2009 թվականի մարտին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice

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5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice

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type

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5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice

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5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice

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5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice

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5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice

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5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice

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Adam L Halberstadt

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Iris van der Heijden

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Jay A Gingrich

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Mark A Geyer

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Michael A Ruderman

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Victoria B Risbrough

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P2860

Serotonin receptors

Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior

Cellular and subcellular distribution of the serotonin 5-HT2A receptor in the central nervous system of adult rat

In vivo evidence that 5-HT(2C) receptors inhibit 5-HT neuronal activity via a GABAergic mechanism

Cellular localization of serotonin(2A) (5HT(2A)) receptors in the rat brain.

Selectivity of action of typical and atypical anti-psychotic drugs as antagonists of the behavioral effects of 1-[2,5-dimethoxy-4-iodophenyl]-2-aminopropane (DOI).

Serotonin (5-HT)2A receptor activation enhances dialysate levels of dopamine and noradrenaline, but not 5-HT, in the frontal cortex of freely-moving rats.

Selective blockade of serotonin-2C/2B receptors enhances mesolimbic and mesostriatal dopaminergic function: a combined in vivo electrophysiological and microdialysis study.

Agonist properties of N,N-dimethyltryptamine at serotonin 5-HT2A and 5-HT2C receptors.

5-HT2A and 5-HT2C/2B receptor subtypes modulate dopamine release induced in vivo by amphetamine and morphine in both the rat nucleus accumbens and striatum.

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10.1038/NPP.2009.29

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8

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34

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2009-03-25T00:00:00Z

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1017994421

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2697271

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