Selective serotonin 5-HT(2C) receptor activation suppresses the reinforcing efficacy of cocaine and sucrose but differentially affects the incentive-salience value of cocaine- vs. sucrose-associated cues.
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SB 206553, a putative 5-HT2C inverse agonist, attenuates methamphetamine-seeking in ratsReward processing by the dorsal raphe nucleus: 5-HT and beyondRole of cues and contexts on drug-seeking behaviourSerotonin 5-HT2 receptor interactions with dopamine function: implications for therapeutics in cocaine use disorderNucleus accumbens shell excitability is decreased by methamphetamine self-administration and increased by 5-HT2C receptor inverse agonism and agonism.Functional status of the serotonin 5-HT2C receptor (5-HT2CR) drives interlocked phenotypes that precipitate relapse-like behaviors in cocaine dependenceEffects of escitalopram on attentional bias to cocaine-related stimuli and inhibitory control in cocaine-dependent subjects.Serotonin at the nexus of impulsivity and cue reactivity in cocaine addiction.The contribution of brain reward circuits to the obesity epidemicConvergent pharmacological mechanisms in impulsivity and addiction: insights from rodent models.Antipsychotics as antidepressants.Can We Selectively Reduce Appetite for Energy-Dense Foods? An Overview of Pharmacological Strategies for Modification of Food Preference BehaviorThe serotonin 5-HT2C receptor and the non-addictive nature of classic hallucinogens.The 5-HT2C receptor agonist lorcaserin reduces nicotine self-administration, discrimination, and reinstatement: relationship to feeding behavior and impulse controlModulation of Food Reward by Endocrine and Environmental Factors: Update and Perspective.Morphine history sensitizes postsynaptic GABA receptors on dorsal raphe serotonin neurons in a stress-induced relapse model in ratsForced Abstinence from Cocaine Self-Administration is Associated with DNA Methylation Changes in Myelin Genes in the Corpus Callosum: a Preliminary StudyDirectly Observable Behavioral Effects of Lorcaserin in RatsLorcaserin Reduces the Discriminative Stimulus and Reinforcing Effects of Cocaine in Rhesus Monkeys.Synergism between a serotonin 5-HT2A receptor (5-HT2AR) antagonist and 5-HT2CR agonist suggests new pharmacotherapeutics for cocaine addiction.Incubation of cocaine cue reactivity associates with neuroadaptations in the cortical serotonin (5-HT) 5-HT2C receptor (5-HT2CR) systemThe effects of pharmacological modulation of the serotonin 2C receptor on goal-directed behavior in micePeptide inhibitors disrupt the serotonin 5-HT2C receptor interaction with phosphatase and tensin homolog to allosterically modulate cellular signaling and behavior.Support for 5-HT2C receptor functional selectivity in vivo utilizing structurally diverse, selective 5-HT2C receptor ligands and the 2,5-dimethoxy-4-iodoamphetamine elicited head-twitch response modelVariation within the serotonin (5-HT) 5-HT₂C receptor system aligns with vulnerability to cocaine cue reactivityMultiple controls exerted by 5-HT2C receptors upon basal ganglia function: from physiology to pathophysiology.Serotonin2C receptors and drug addiction: focus on cocaine.Effects of the serotonin 2C receptor agonist WAY163909 on the abuse-related effects and mesolimbic dopamine neurochemistry induced by abused stimulants in rhesus monkeys.A short history of the 5-HT2C receptor: from the choroid plexus to depression, obesity and addiction treatment.Characterization of the discriminative stimulus effects of lorcaserin in rats.Decreased Incentive Motivation Following Knockout or Acute Blockade of the Serotonin Transporter: Role of the 5-HT2C Receptor.Repeated 7-Day Treatment with the 5-HT2C Agonist Lorcaserin or the 5-HT2A Antagonist Pimavanserin Alone or in Combination Fails to Reduce Cocaine vs Food Choice in Male Rhesus Monkeys.Lorcaserin Suppresses Oxycodone Self-Administration and Relapse Vulnerability in Rats.Inhibition of cocaine and 3,4-methylenedioxypyrovalerone (MDPV) self-administration by lorcaserin is mediated by 5-HT2C receptors in rats.Effects of Lorcaserin on Cocaine and Methamphetamine Self-Administration and Reinstatement of Responding Previously Maintained by Cocaine in Rhesus Monkeys.Role of impulsivity and reward in the anti-obesity actions of 5-HT2C receptor agonists.Pharmacological evidence that 5-HT2C receptor blockade selectively improves decision making when rewards are paired with audiovisual cues in a rat gambling task.The behavioral pharmacology and therapeutic potential of lorcaserin for substance use disorders.Evidence for a role of 5-HT2C receptors in the motor aspects of performance, but not the efficacy of food reinforcers, in a progressive ratio schedule.Critical involvement of 5-HT2C receptor function in amphetamine-induced 50-kHz ultrasonic vocalizations in rats.
P2860
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P2860
Selective serotonin 5-HT(2C) receptor activation suppresses the reinforcing efficacy of cocaine and sucrose but differentially affects the incentive-salience value of cocaine- vs. sucrose-associated cues.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
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name
Selective serotonin 5-HT(2C) r ...... - vs. sucrose-associated cues.
@en
type
label
Selective serotonin 5-HT(2C) r ...... - vs. sucrose-associated cues.
@en
prefLabel
Selective serotonin 5-HT(2C) r ...... - vs. sucrose-associated cues.
@en
P2093
P2860
P1433
P1476
Selective serotonin 5-HT(2C) r ...... - vs. sucrose-associated cues.
@en
P2093
F Gerard Moeller
Kathryn A Cunningham
Marcy J Bubar
Noelle C Anastasio
Robert G Fox
Scott R Gilbertson
Sharon Rosenzweig-Lipson
Sonja J Stutz
P2860
P304
P356
10.1016/J.NEUROPHARM.2011.04.034
P577
2011-05-11T00:00:00Z