Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice. - Test2 - elhamkhani - TriplyDB

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice.

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice.

http://www.wikidata.org/entity/Q30488610

about

Genetic-background modulation of core and variable autistic-like symptoms in Fmr1 knock-out mice.Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function Emerging pharmacotherapies for neurodevelopmental disorders A pilot open label, single dose trial of fenobam in adults with fragile X syndrome.Networking in autism: leveraging genetic, biomarker and model system findings in the search for new treatments Fragile X syndrome and targeted treatment trials.Learning and behavioral deficits associated with the absence of the fragile X mental retardation protein: what a fly and mouse model can teach us.Unstable mutations in the FMR1 gene and the phenotypes Treatment of neurodevelopmental disorders in adulthood The pathophysiology of fragile X (and what it teaches us about synapses)Targeted pharmacological treatment of autism spectrum disorders: fragile X and Rett syndromes Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and Back Advancing the understanding of autism disease mechanisms through genetics Genetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model.Translational Mouse Models of Autism: Advancing Toward Pharmacological Therapeutics.Neuronal connectivity as a convergent target of gene × environment interactions that confer risk for Autism Spectrum Disorders Behavioural phenotyping assays for mouse models of autism GABA receptor subunit distribution and FMRP-mGluR5 signaling abnormalities in the cerebellum of subjects with schizophrenia, mood disorders, and autism.Validating γ oscillations and delayed auditory responses as translational biomarkers of autism Selective Disruption of Metabotropic Glutamate Receptor 5-Homer Interactions Mimics Phenotypes of Fragile X Syndrome in Mice.Progress toward therapeutic potential for AFQ056 in Fragile X syndrome.Early social enrichment rescues adult behavioral and brain abnormalities in a mouse model of fragile X syndrome.Comprehensive behavioral analysis of RNG105 (Caprin1) heterozygous mice: Reduced social interaction and attenuated response to novelty Stem cells and modeling of autism spectrum disorders.Valproate-induced neurodevelopmental deficits in Xenopus laevis tadpoles.Impaired sensorimotor gating in Fmr1 knock out and Fragile X premutation model mice.From FMRP function to potential therapies for fragile X syndrome.Modeling fragile X syndrome in the Fmr1 knockout mouse Fragile X: leading the way for targeted treatments in autism.Influence of stimulant-induced hyperactivity on social approach in the BTBR mouse model of autism Impaired critical period plasticity in primary auditory cortex of fragile X model mice Fragile X syndrome: mechanistic insights and therapeutic avenues regarding the role of potassium channels.Metabotropic glutamate receptors: from the workbench to the bedside.The autism diagnosis in translation: shared affect in children and mouse models of ASD.Prepulse inhibition in patients with fragile X-associated tremor ataxia syndrome.Genetic models of sensorimotor gating: relevance to neuropsychiatric disorders.The GABA(A) receptor agonist THIP ameliorates specific behavioral deficits in the mouse model of fragile X syndrome.CGG repeat in the FMR1 gene: size matters (3-Cyano-5-fluorophenyl)biaryl negative allosteric modulators of mGlu(5): Discovery of a new tool compound with activity in the OSS mouse model of addiction The role of fragile X mental retardation protein in major mental disorders.

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Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice.

http://www.wikidata.org/entity/Q30488610

description

2008 nî lūn-bûn

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2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2008 թվականի ապրիլին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice.

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Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice.

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type

label

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice.

@ast

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice.

@en

prefLabel

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice.

@ast

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice.

@en

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J.NBD.2008.04.002

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Neurobiology of Disease

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Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice.

@en

P2093

Ben A Oostra

http://www.w3.org/2001/XMLSchema#string

Chris I De Zeeuw

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David L Nelson

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Femke M S de Vrij

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Herma C van der Linde

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Josien Levenga

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Rob Willemsen

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Sebastiaan K Koekkoek

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P2860

Correction of fragile X syndrome in mice.

Altered synaptic plasticity in a mouse model of fragile X mental retardation

Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits

Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation

A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability

Evidence that fragile X mental retardation protein is a negative regulator of translation

Local functions for FMRP in axon growth cone motility and activity-dependent regulation of filopodia and spine synapses

From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome

Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity

Localization of FMRP-associated mRNA granules and requirement of microtubules for activity-dependent trafficking in hippocampal neurons

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127-132

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10.1016/J.NBD.2008.04.002

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1

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31

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2008-04-25T00:00:00Z

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5285643

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18571098

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2481236

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