Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases.
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Hematopoietic lineage cell-specific protein 1 functions in concert with the Wiskott-Aldrich syndrome protein to promote podosome array organization and chemotaxis in dendritic cellsCortactin phosphorylated by ERK1/2 localizes to sites of dynamic actin regulation and is required for carcinoma lamellipodia persistenceCortactin as a target for FAK in the regulation of focal adhesion dynamicsMicrotubules as platforms for assaying actin polymerization in vivoPolarized endocytosis of the keratinocyte growth factor receptor in migrating cells: role of SRC-signaling and cortactinpTyr421 cortactin is overexpressed in colon cancer and is dephosphorylated by curcumin: involvement of non-receptor type 1 protein tyrosine phosphatase (PTPN1)A nucleator arms race: cellular control of actin assemblyTyrosine phosphorylation of cortactin by the FAK-Src complex at focal adhesions regulates cell motilityThe homolog of the five SH3-domain protein (HOFI/SH3PXD2B) regulates lamellipodia formation and cell spreadingCortactin controls cell motility and lamellipodial dynamics by regulating ECM secretionImmunoinhibitory adapter protein Src homology domain 3 lymphocyte protein 2 (SLy2) regulates actin dynamics and B cell spreading.Cortactin deficiency is associated with reduced neutrophil recruitment but increased vascular permeability in vivoThe membrane-associated protein, supervillin, accelerates F-actin-dependent rapid integrin recycling and cell motility.Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin.Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation.Microtubule dynamic instability controls podosome patterning in osteoclasts through EB1, cortactin, and Src.Quantitative kinetic study of the actin-bundling protein L-plastin and of its impact on actin turn-over.Role of c-Met/phosphatidylinositol 3-kinase (PI3k)/Akt signaling in hepatocyte growth factor (HGF)-mediated lamellipodia formation, reactive oxygen species (ROS) generation, and motility of lung endothelial cells.Cortactin is implicated in murine zygotic development.Hax-1 is required for Rac1-Cortactin interaction and ovarian carcinoma cell migration.Cortactin modulates RhoA activation and expression of Cip/Kip cyclin-dependent kinase inhibitors to promote cell cycle progression in 11q13-amplified head and neck squamous cell carcinoma cells.RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytesInversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration.Cortactin: a multifunctional regulator of cellular invasivenessHDAC6 deacetylase activity is critical for lipopolysaccharide-induced activation of macrophagesExtracellular signal-regulated kinase (ERK) regulates cortactin ubiquitination and degradation in lung epithelial cellsThe Phosphorylation and Distribution of Cortactin Downstream of Integrin α9β1 Affects Cancer Cell BehaviourLoss of cortactin causes endothelial barrier dysfunction via disturbed adrenomedullin secretion and actomyosin contractility.Novel role of cortactin in G protein-coupled receptor agonist-induced nuclear export and degradation of p21Cip1.The S40 residue in HIV-1 Gag p6 impacts local and distal budding determinants, revealing additional late domain activities.The actin binding proteins cortactin and HS1 are dispensable for platelet actin nodule and megakaryocyte podosome formation.Cortactin in cell migration and cancer at a glanceThe non-canonical roles of clathrin and actin in pathogen internalization, egress and spread.Steering cell migration: lamellipodium dynamics and the regulation of directional persistence.Role of cellular cytoskeleton in epithelial-mesenchymal transition process during cancer progression.The Arp2/3 inhibitory protein arpin induces cell turning by pausing cell migration.The protein tyrosine phosphatase DEP-1/PTPRJ promotes breast cancer cell invasion and metastasis.The actin regulatory protein HS1 is required for antigen uptake and presentation by dendritic cells.Cortactin deficiency causes increased RhoA/ROCK1-dependent actomyosin contractility, intestinal epithelial barrier dysfunction, and disproportionately severe DSS-induced colitis.How distinct Arp2/3 complex variants regulate actin filament assembly.
P2860
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P2860
Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases.
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Cortactin promotes migration a ...... n by signaling to Rho-GTPases.
@ast
Cortactin promotes migration a ...... n by signaling to Rho-GTPases.
@en
type
label
Cortactin promotes migration a ...... n by signaling to Rho-GTPases.
@ast
Cortactin promotes migration a ...... n by signaling to Rho-GTPases.
@en
prefLabel
Cortactin promotes migration a ...... n by signaling to Rho-GTPases.
@ast
Cortactin promotes migration a ...... n by signaling to Rho-GTPases.
@en
P2093
P2860
P50
P356
P1476
Cortactin promotes migration a ...... on by signaling to Rho-GTPases
@en
P2093
Frank P L Lai
J Margit Oelkers
J Victor Small
Malgorzata Szczodrak
Markus Ladwein
Simona Polo
Sonja Auinger
Stefanie Benesch
P2860
P304
P356
10.1091/MBC.E08-12-1180
P577
2009-05-20T00:00:00Z