SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
about
Evidence that SOX2 overexpression is oncogenic in the lungSOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomasKras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lungThe PRKCI and SOX2 oncogenes are coamplified and cooperate to activate Hedgehog signaling in lung squamous cell carcinomaReversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcomaMolecular biology of lung cancer: clinical implicationsSox2 is an androgen receptor-repressed gene that promotes castration-resistant prostate cancerFunctions and mechanisms of long noncoding RNAs in lung cancerTyrosine Kinase Receptor Landscape in Lung Cancer: Therapeutical ImplicationsYin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implicationParadoxical role of SOX2 in gastric cancerRetinoblastoma tumor suppressor functions shared by stem cell and cancer cell strategiesSquamous cell carcinomas of the lung and of the head and neck: new insights on molecular characterizationEpigenetic modulators, modifiers and mediators in cancer aetiology and progressionTargeted drugs in small-cell lung cancerEsophageal Cancer: Insights From Mouse ModelsDifferences in driver genes between smoking-related and non-smoking-related lung cancer in the Chinese populationMolecular cancer prevention: Current status and future directionsThe role of SOX2 in small cell lung cancer, lung adenocarcinoma and squamous cell carcinoma of the lungTwists in views on RB functions in cellular signaling, metabolism and stem cellsRole of SOX family of transcription factors in central nervous system tumorsGenetic characteristics and research progress of targeted therapy in squamous cell carcinomaThe genomic stability of induced pluripotent stem cellsFrequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer.Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer.Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer.Targeting SOX2 as a Therapeutic Strategy in GlioblastomaLong non-coding RNA SOX2OT: expression signature, splicing patterns, and emerging roles in pluripotency and tumorigenesisSquamous cell lung cancer: from tumor genomics to cancer therapeuticsThe RNA binding protein FXR1 is a new driver in the 3q26-29 amplicon and predicts poor prognosis in human cancersComprehensive genomic characterization of squamous cell lung cancers.Divergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor developmentTrends and predictors of changes in pulmonary function after treatment for pulmonary tuberculosisAn integrated inspection of the somatic mutations in a lung squamous cell carcinoma using next-generation sequencingPulmonary adenocarcinoma: a renewed entity in 2011EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner earGenomic and molecular characterization of esophageal squamous cell carcinomaEMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancerThe Effect of MicroRNA-375 Overexpression, an Inhibitor of Helicobacter pylori-Induced Carcinogenesis, on lncRNA SOX2OT.Disease-causing mutation in extracellular and intracellular domain of FGFR1 protein: computational approach.
P2860
Q21091126-C4587CAD-3707-431A-8ADF-F2C65D96A5AEQ21562575-371F36E0-AFE0-4D08-9E5C-321DABB2FAC6Q24303485-7CC4FABF-9289-4058-B8CD-94894DAEEB26Q24337113-44E329F7-7FD2-4ED8-AA4D-2B7B5A5B2AA1Q24337483-A2FC392E-CBBC-431A-B709-3BF809A3C8B5Q24610335-CFE83205-D1C4-4A30-8169-20FC995FE66EQ24633279-B6CAA60E-84F0-46AE-B72E-C08DE58CFD3BQ26738672-69F6E05E-A5D7-4C9B-A177-DF3AFA59A518Q26741318-C367E352-7698-4DF3-BFEE-7E7457D70A78Q26745972-D2259659-61A7-4C1C-AE17-B2A2D4F9B42FQ26749130-F1008FEF-15F4-40E9-869E-FFD816A33DC9Q26750380-EF6AB7DE-D83A-4B1F-9322-78D7821A3440Q26765060-A9FD04DA-75FB-4C68-80B9-D657F0D8B7BAQ26766149-7516EEE6-554E-4D6D-A3A5-5C8843C8207EQ26767017-72CA1800-B7FF-47B4-9916-43286BE20090Q26783904-3F606CBE-57CF-4268-BE6E-24CB71B5B945Q26786594-5F6A9C9A-1CF5-4147-812C-2A88ACFC33E8Q26797207-1E48C05F-AC40-4514-858F-035E0C7ADEA1Q26822879-D0FB7EA0-21CF-47BA-B781-0DC02C97E731Q26828495-40D7EE9C-428D-4FDA-A9FE-81647AA2ED2DQ26860974-D5D8F2C2-B8D5-4E65-A65D-819ED5F588A4Q26865529-6E073BDC-68DC-40F5-89A1-0E4AFCFC4422Q26998764-53D6D4BA-39B2-42D7-BBC8-904080DB9B51Q27851615-31A1561D-3F7C-4E76-8CD7-547437AA1101Q27851654-EA7708A4-E8C7-4930-9802-95B34D4D5137Q27851720-9E36D0EE-9BEE-45BD-A7F2-1E280B1CDBCBQ28079501-06E63687-07B7-4B94-B752-3F4AC85B1BB9Q28082535-FD608F9E-9C8A-4910-A9CF-EFF826837267Q28086951-46EA0550-F5DD-471F-B050-E05EE6EA2BF9Q28258198-C6961FE9-E4E2-4712-9126-2473D0875D9AQ28274701-25A17748-9A6F-432B-BDEA-BA320C46E837Q28384678-BD7D2CED-FE9C-4128-B106-D9D8C46B56C6Q28388618-1D980CEF-45FC-4B69-A3D6-F9D72E250B8FQ28390823-C7B8A5AE-455C-4098-9ED2-01A505407B1EQ28395348-87BB7486-F0B7-4980-A8D0-593EB4427558Q28505753-19FC1844-390A-43DE-A7E2-E329B1A2E5FAQ28657686-C3296412-AD61-47BA-80C6-AB067B916448Q29616360-2759B50E-FF0C-422E-8B4B-31493112F9E4Q30371417-79F981F3-21B1-42B0-83DF-4C6E5DEFBA45Q30426059-CE941564-377B-4800-B265-D22BD3D6D476
P2860
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
name
SOX2 is an amplified lineage-s ...... ageal squamous cell carcinomas
@ast
SOX2 is an amplified lineage-s ...... ageal squamous cell carcinomas
@en
type
label
SOX2 is an amplified lineage-s ...... ageal squamous cell carcinomas
@ast
SOX2 is an amplified lineage-s ...... ageal squamous cell carcinomas
@en
prefLabel
SOX2 is an amplified lineage-s ...... ageal squamous cell carcinomas
@ast
SOX2 is an amplified lineage-s ...... ageal squamous cell carcinomas
@en
P2093
P2860
P50
P356
P1433
P1476
SOX2 is an amplified lineage-s ...... ageal squamous cell carcinomas
@en
P2093
Adam J Bass
Adi F Gazdar
Alex H Ramos
Anil K Rustgi
Barbara A Weir
Chang Qi Zhu
Changqing Ma
Christopher J Lafargue
David G Beer
Douglas B Stairs
P2860
P2888
P304
P356
10.1038/NG.465
P407
P50
P577
2009-10-04T00:00:00Z