High-resolution genomic profiles of human lung cancer - Test2 - elhamkhani - TriplyDB

High-resolution genomic profiles of human lung cancer

High-resolution genomic profiles of human lung cancer

http://www.wikidata.org/entity/Q24530598

about

Nek4 regulates entry into replicative senescence and the response to DNA damage in human fibroblasts Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development Passenger deletions generate therapeutic vulnerabilities in cancer Molecular biology of lung cancer: clinical implications MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib Characterizing the cancer genome in lung adenocarcinoma.Validation of TPX2 as a potential therapeutic target in pancreatic cancer cells.Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways Impact of whole genome amplification on analysis of copy number variants Oncogenic cooperation and coamplification of developmental transcription factor genes in lung cancer Mad2 overexpression promotes aneuploidy and tumorigenesis in mice BAC to the future! or oligonucleotides: a perspective for micro array comparative genomic hybridization (array CGH)Patterns of Chromosomal Aberrations in Solid Tumors Genetic characteristics and research progress of targeted therapy in squamous cell carcinoma Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer.Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer.Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer.FGFR1 mRNA and protein expression, not gene copy number, predict FGFR TKI sensitivity across all lung cancer histologies.Integration of gene dosage and gene expression in non-small cell lung cancer, identification of HSP90 as potential target Comprehensive genomic characterization of squamous cell lung cancers.miR-203 represses 'stemness' by repressing DeltaNp63 Divergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor development Genomic aberrations in lung adenocarcinoma in never smokers Arsenic biotransformation as a cancer promoting factor by inducing DNA damage and disruption of repair mechanisms Role of cell cycle regulators in lung carcinogenesis Pulmonary adenocarcinoma: a renewed entity in 2011 Molecular features in arsenic-induced lung tumors Ashwagandha derived withanone targets TPX2-Aurora A complex: computational and experimental evidence to its anticancer activity Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia Differential pathogenesis of lung adenocarcinoma subtypes involving sequence mutations, copy number, chromosomal instability, and methylation The landscape of somatic copy-number alteration across human cancers.Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma Flexible and accurate detection of genomic copy-number changes from aCGH.Integrated analysis of DNA copy number and gene expression microarray data using gene sets SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas A meta-analysis of multiple matched copy number and transcriptomics data sets for inferring gene regulatory relationships.A screen for retrotransposed imprinted genes reveals an association between X chromosome homology and maternal germ-line methylation Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival.Functional copy-number alterations in cancer.Model-based clustering of array CGH data.

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High-resolution genomic profiles of human lung cancer

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High-resolution genomic profiles of human lung cancer

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High-resolution genomic profiles of human lung cancer

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High-resolution genomic profiles of human lung cancer

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High-resolution genomic profiles of human lung cancer

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High-resolution genomic profiles of human lung cancer

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High-resolution genomic profiles of human lung cancer

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High-resolution genomic profiles of human lung cancer

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High-resolution genomic profiles of human lung cancer

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High-resolution genomic profiles of human lung cancer

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High-resolution genomic profiles of human lung cancer

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Proceedings of the National Academy of Sciences of the United States of America

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High-resolution genomic profiles of human lung cancer

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Alexei Protopopov

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Andrew J Aguirre

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Bin Feng

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Eric S Martin

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Gautam Maulik

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Giovanni Tonon

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Hongbin Ji

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Kwok-Kin Wong

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Mingjian James You

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Ronald A Depinho

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P2860

Identification of genes (SPON2 and C20orf2) differentially expressed between cancerous and noncancerous lung cells by mRNA differential display

WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myeloma

Significance analysis of microarrays applied to the ionizing radiation response

A census of human cancer genes

Statistical significance for genomewide studies

ONCOMINE: a cancer microarray database and integrated data-mining platform

Large-scale copy number polymorphism in the human genome

p63 is the molecular switch for initiation of an epithelial stratification program

High-throughput tissue microarray analysis of 3p25 (RAF1) and 8p12 (FGFR1) copy number alterations in urinary bladder cancer

Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

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