ATP-induced conformational changes in Hsp70: molecular dynamics and experimental validation of an in silico predicted conformation.
about
BiP and its nucleotide exchange factors Grp170 and Sil1: mechanisms of action and biological functionsMolecular mechanism of allosteric communication in Hsp70 revealed by molecular dynamics simulationsIdentification of key hinge residues important for nucleotide-dependent allostery in E. coli Hsp70/DnaKMutagenesis reveals the complex relationships between ATPase rate and the chaperone activities of Escherichia coli heat shock protein 70 (Hsp70/DnaK)Chemical screens against a reconstituted multiprotein complex: myricetin blocks DnaJ regulation of DnaK through an allosteric mechanismAllosteric signal transmission in the nucleotide-binding domain of 70-kDa heat shock protein (Hsp70) molecular chaperonesCommon functionally important motions of the nucleotide-binding domain of Hsp70ATPase subdomain IA is a mediator of interdomain allostery in Hsp70 molecular chaperones.Dancing through Life: Molecular Dynamics Simulations and Network-Centric Modeling of Allosteric Mechanisms in Hsp70 and Hsp110 Chaperone Proteins.Simulation of the opening and closing of Hsp70 chaperones by coarse-grained molecular dynamicsDynamical Structures of Hsp70 and Hsp70-Hsp40 Complexes.Structural mechanisms of chaperone mediated protein disaggregation.eHSP70/iHSP70 and divergent functions on the challenge: effect of exercise and tissue specificity in response to stress.Heat shock protein 70 inhibitors. 1. 2,5'-thiodipyrimidine and 5-(phenylthio)pyrimidine acrylamides as irreversible binders to an allosteric site on heat shock protein 70Identification of an allosteric pocket on human hsp70 reveals a mode of inhibition of this therapeutically important protein.Real-time observation of the conformational dynamics of mitochondrial Hsp70 by spFRET.Substrate discrimination of the chaperone BiP by autonomous and cochaperone-regulated conformational transitions.Tracking the interplay between bound peptide and the lid domain of DnaK, using molecular dynamics.Prediction of allosteric sites on protein surfaces with an elastic-network-model-based thermodynamic method.Disrupted hydrogen bond network and impaired ATPase activity in an Hsc70 cysteine mutant.Structural insights into a unique Hsp70-Hsp40 interaction in the eukaryotic ribosome-associated complex.Identification of key residues for protein conformational transition using elastic network model.
P2860
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P2860
ATP-induced conformational changes in Hsp70: molecular dynamics and experimental validation of an in silico predicted conformation.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
ATP-induced conformational cha ...... silico predicted conformation.
@ast
ATP-induced conformational cha ...... silico predicted conformation.
@en
type
label
ATP-induced conformational cha ...... silico predicted conformation.
@ast
ATP-induced conformational cha ...... silico predicted conformation.
@en
prefLabel
ATP-induced conformational cha ...... silico predicted conformation.
@ast
ATP-induced conformational cha ...... silico predicted conformation.
@en
P2093
P2860
P356
P1433
P1476
ATP-induced conformational cha ...... silico predicted conformation
@en
P2093
Hyung-June Woo
Jianwen Jiang
P2860
P304
11470-11477
P356
10.1021/BI901256Y
P407
P577
2009-12-01T00:00:00Z