How potassium affects the activity of the molecular chaperone Hsc70. II. Potassium binds specifically in the ATPase active site
about
The nucleotide exchange factors of Hsp70 molecular chaperonesBiP and its nucleotide exchange factors Grp170 and Sil1: mechanisms of action and biological functionsPrinciples of allosteric interactions in cell signalingInsights into the influence of nucleotides on actin family proteins from seven structures of Arp2/3 complexRigidification of the autolysis loop enhances Na+ binding to thrombinThe nucleotide exchange factor MGE exerts a key function in the ATP-dependent cycle of mt-Hsp70-Tim44 interaction driving mitochondrial protein import.ATP-induced conformational changes in Hsp70: molecular dynamics and experimental validation of an in silico predicted conformation.Robust structural analysis of native biological macromolecules from multi-crystal anomalous diffraction data.Pathways of allosteric regulation in Hsp70 chaperones.Small molecule DnaK modulators targeting the beta-domain.Using ¹⁵N-ammonium to characterise and map potassium binding sites in proteins by NMR spectroscopy.Role of Hsp70 ATPase domain intrinsic dynamics and sequence evolution in enabling its functional interactions with NEFs.Redesigning the monovalent cation specificity of an enzymeMeasurement and interpretation of 15N-1H residual dipolar couplings in larger proteins.Ability of Sit4p to promote K+ efflux via Nha1p is modulated by Sap155p and Sap185p.Stability and dynamics of G-actin: back-door water diffusion and behavior of a subdomain 3/4 loopHsp70 and its molecular role in nervous system diseasesLacZ β-galactosidase: structure and function of an enzyme of historical and molecular biological importance.The topomer-sampling model of protein foldingAn RNA aptamer specific to Hsp70-ATP conformation inhibits its ATPase activity independent of Hsp40.Identification of yeast genes involved in k homeostasis: loss of membrane traffic genes affects k uptake.Synthetic receptors as models for alkali metal cation-pi binding sites in proteinsExperimentally biased model structure of the Hsc70/auxilin complex: substrate transfer and interdomain structural changeThrombin.Bacterial expression and purification of interleukin-2 tyrosine kinase: single step separation of the chaperonin impurityStructural transitions in ion coordination driven by changes in competition for ligand binding.Modulation of RNA primer formation by Mn(II)-substituted T7 DNA primase.Molecular Mechanisms of Enzyme Activation by Monovalent Cations.Modeling and docking studies on novel mutants (K71L and T204V) of the ATPase domain of human heat shock 70 kDa protein 1.The role of monovalent cations in the ATPase reaction of DNA gyrase.The peptide-binding and ATPase domains of recombinant hsc70 are required to interact with rotavirus and reduce its infectivity.Exploring potassium-dependent GTP hydrolysis in TEES family GTPases.Sulfatide-Hsp70 interaction promotes Hsp70 clustering and stabilizes binding to unfolded protein.Dimerisation-dependent GTPase reaction of MnmE: how potassium acts as GTPase-activating element.Measurement of 15N longitudinal relaxation rates in 15NH4+ spin systems to characterise rotational correlation times and chemical exchange.Heteronuclear transverse and longitudinal relaxation in AX4 spin systems: application to (15)N relaxations in (15)NH4(+).Toward understanding allosteric signaling mechanisms in the ATPase domain of molecular chaperones.Disrupted hydrogen bond network and impaired ATPase activity in an Hsc70 cysteine mutant.The Hsp40 J-domain modulates Hsp70 conformation and ATPase activity with a semi-elliptical spring.
P2860
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P2860
How potassium affects the activity of the molecular chaperone Hsc70. II. Potassium binds specifically in the ATPase active site
description
1995 nî lūn-bûn
@nan
1995 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
How potassium affects the acti ...... ally in the ATPase active site
@ast
How potassium affects the acti ...... ally in the ATPase active site
@en
How potassium affects the acti ...... ally in the ATPase active site
@nl
type
label
How potassium affects the acti ...... ally in the ATPase active site
@ast
How potassium affects the acti ...... ally in the ATPase active site
@en
How potassium affects the acti ...... ally in the ATPase active site
@nl
prefLabel
How potassium affects the acti ...... ally in the ATPase active site
@ast
How potassium affects the acti ...... ally in the ATPase active site
@en
How potassium affects the acti ...... ally in the ATPase active site
@nl
P1476
How potassium affects the acti ...... ally in the ATPase active site
@en
P2093
S M Wilbanks
P304
P407
P577
1995-02-03T00:00:00Z