The Rac activator STEF (Tiam2) regulates cell migration by microtubule-mediated focal adhesion disassembly.
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CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnoverTargeting and transport: how microtubules control focal adhesion dynamicsTRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and ContractilityGTSE1 is a microtubule plus-end tracking protein that regulates EB1-dependent cell migrationPaxillin and Hic-5 interaction with vinculin is differentially regulated by Rac1 and RhoALis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization.ATF3 is a novel regulator of mouse neutrophil migrationMYPT1 regulates contractility and microtubule acetylation to modulate integrin adhesions and matrix assemblyTiam-Rac signaling mediates trans-endocytosis of ephrin receptor EphB2 and is important for cell repulsion.Distinct ligand specificity of the Tiam1 and Tiam2 PDZ domainsComparative DNA methylome analysis of endometrial carcinoma reveals complex and distinct deregulation of cancer promoters and enhancers.SUMOylation of the GTPase Rac1 is required for optimal cell migration.Fidgetin-Like 2: A Microtubule-Based Regulator of Wound HealingMicrotubule-dependent modulation of adhesion complex composition.Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migrationARAP2 signals through Arf6 and Rac1 to control focal adhesion morphology.Post-polymerization crosstalk between the actin cytoskeleton and microtubule network.The roles and regulation of the actin cytoskeleton, intermediate filaments and microtubules in smooth muscle cell migration.The diverse roles of Rac signaling in tumorigenesisRegulation of cell migration by dynamic microtubules.Rho-associated coiled-coil kinase (ROCK) signaling and disease.IAPs on the move: role of inhibitors of apoptosis proteins in cell migration.Microtubules and actin crosstalk in cell migration and division.Mechanisms of endothelial cell migration.A dual regulator of neutrophil recruitmentA novel high-content analysis tool reveals Rab8-driven cytoskeletal reorganization through Rho GTPases, calpain and MT1-MMP.A CDC42-centered signaling unit is a dominant positive regulator of endothelial integrity.CtBP2 Promotes Human Cancer Cell Migration by Transcriptional Activation of Tiam1.The molecular dynamics of crawling migration in microtubule-disrupted keratocytes.Mechanisms of inhibition of endothelial cell migration by taxanes.Stage-specific control of early B cell development by the transcription factor Ikaros.Spindly is required for rapid migration of human cells.UHRF1-mediated tumor suppressor gene inactivation in nonsmall cell lung cancer.STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap.
P2860
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P2860
The Rac activator STEF (Tiam2) regulates cell migration by microtubule-mediated focal adhesion disassembly.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The Rac activator STEF (Tiam2) ...... ed focal adhesion disassembly.
@ast
The Rac activator STEF (Tiam2) ...... ed focal adhesion disassembly.
@en
type
label
The Rac activator STEF (Tiam2) ...... ed focal adhesion disassembly.
@ast
The Rac activator STEF (Tiam2) ...... ed focal adhesion disassembly.
@en
prefLabel
The Rac activator STEF (Tiam2) ...... ed focal adhesion disassembly.
@ast
The Rac activator STEF (Tiam2) ...... ed focal adhesion disassembly.
@en
P2093
P2860
P50
P356
P1433
P1476
The Rac activator STEF (Tiam2) ...... ed focal adhesion disassembly.
@en
P2093
Alicja Nazgiewicz
Claire Rooney
Gavin White
Simon A Woodcock
P2860
P304
P356
10.1038/EMBOR.2010.10
P577
2010-03-12T00:00:00Z