SUMOylation of the GTPase Rac1 is required for optimal cell migration.
about
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradationThe Rac1 hypervariable region in targeting and signaling: a tail of many storiesRho GTPase regulation by miRNAs and covalent modificationsModification by ubiquitin-like proteins: significance in apoptosis and autophagy pathwaysTnaA, an SP-RING protein, interacts with Osa, a subunit of the chromatin remodeling complex BRAHMA and with the SUMOylation pathway in Drosophila melanogasterHexavalent chromium induces expression of mesenchymal and stem cell markers in renal epithelial cellsThe interdependence of the Rho GTPases and apicobasal cell polarity.Suppression of Rac1 Signaling by Influenza A Virus NS1 Facilitates Viral ReplicationSUMO1 modification stabilizes CDK6 protein and drives the cell cycle and glioblastoma progression.Nucleo-cytoplasmic trafficking of TRIM8, a novel oncogene, is involved in positive regulation of TNF induced NF-κB pathway.Pilus phase variation switches gonococcal adherence to invasion by caveolin-1-dependent host cell signaling.Spatial and temporal control of Rho GTPase functionsA novel post-translational modification of nucleolin, SUMOylation at Lys-294, mediates arsenite-induced cell death by regulating gadd45α mRNA stability.PIAS3, an inhibitor of STAT3, has intensively negative association with the survival of gastric cancer.SUMOylation Blocks the Ubiquitin-Mediated Degradation of the Nephronophthisis Gene Product Glis2/NPHP7RhoGDI SUMOylation at Lys-138 increases its binding activity to Rho GTPase and its inhibiting cancer cell motility.Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cellsCharacterization of Novel Molecular Mechanisms Favoring Rac1 Membrane Translocation.SUMOylation of the small GTPase ARL-13 promotes ciliary targeting of sensory receptors.Redox regulation of Rac1 by thiol oxidation.Glutaminase 2 is a novel negative regulator of small GTPase Rac1 and mediates p53 function in suppressing metastasis.The GTP-bound and Sumoylated Form of the rab17 Small Molecular Weight GTPase Selectively Binds Syntaxin 2 in Polarized Hepatic WIF-B Cells.Deregulation of Rho GTPases in cancerEmerging roles of sumoylation in the regulation of actin, microtubules, intermediate filaments, and septinsThe diverse roles of Rac signaling in tumorigenesisUbiquitination: Added complexity in Ras and Rho family GTPase function.Ubiquitin links to cytoskeletal dynamics, cell adhesion and migration.Intratumoral stages of metastatic cells: a synthesis of ontogeny, Rho/Rac GTPases, epithelial-mesenchymal transitions, and more.SUMO rules: regulatory concepts and their implication in neurologic functions.Small Rho GTPases in the control of cell shape and mobility.Sumo and the cellular stress response.E3 ubiquitin ligases in regulating stress fiber, lamellipodium, and focal adhesion dynamics.SUMO wrestling in cell movement.Rac1 in human diseases: The therapeutic potential of targeting Rac1 signaling regulatory mechanisms.Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes.Regulation of Cellular Processes by SUMO: Understudied Topics.Tiam1/Vav2-Rac1 axis: A tug-of-war between islet function and dysfunction.SUMOylation of ATF3 alters its transcriptional activity on regulation of TP53 gene.The small GTPase Rac1 is involved in the maintenance of stemness and malignancies in glioma stem-like cells.Integrin β7-mediated regulation of multiple myeloma cell adhesion, migration, and invasion.
P2860
Q24298339-95BC5C7E-3004-4CE4-B15D-56C9B68D8564Q26864271-8EAE1519-ECAC-442B-95EB-523D9914BB5EQ26999290-EEC39F0A-05A1-4086-AAAF-011E915F665FQ27011543-6D604677-735A-4B24-919A-C75273AF3FEBQ28486305-6A901151-AB49-4A85-9E2C-630F49DB3DB2Q28595762-7F84F018-EC2B-49C7-8AB2-12514A8A1EE4Q30009264-253D09DB-603D-4AAD-A143-9C3D17E8E947Q30395437-DF9DE534-129D-44D3-83FA-F428946305E1Q33876908-0C52B51B-150C-4CE2-B945-6E59CF5079A8Q34477410-09321C35-714B-4261-BB43-0B83754B772EQ34743753-92731E76-F42A-4738-9012-3C13F7FF4D8EQ34787970-A4B0B108-AD35-4847-85A1-E177208FFF26Q35103925-B60BBDCE-857E-457B-B1EE-0C1454DC055FQ35173571-D933463E-2F50-4FEA-8148-53ED9A576151Q35665965-8288C11F-F022-4000-97AD-91EDBA740038Q35922304-9108BF09-147A-4DAF-AA7F-0899994CE9D2Q36165625-7D2E0BE7-92F1-4DF2-8A21-425880E92608Q36189951-1C8DE973-0AFE-448B-A3BF-0441CCD15041Q36389259-E9A1283D-8DA9-40FD-868B-491F827A4E7FQ36451514-D0D8B22A-6EE2-4794-BE69-2327A335C5BBQ36568490-05D66F30-1325-4B99-8AB3-52F11BB33BA1Q36850069-7DF9EE2E-B49B-4603-B347-AE0AD1E29E99Q37214445-E7C7AAD8-662F-4A0A-BDAF-F5717A731B67Q37308644-A5406D99-790B-41A9-BF2E-6B1689AFD27AQ37863400-86EEF668-6EC5-46B9-A6D3-193545E62A6FQ37965170-BCA91BA9-994D-4258-B6C2-61FDB4DA369BQ37978888-553A74C3-0F65-441A-8D51-948305FC6DEDQ38019416-87A9DC03-628E-4E22-9B49-EF6A65AD500CQ38132691-ED9968DA-119B-4583-A90B-FF82ABA5945CQ38166254-2D04A5BF-4991-4800-8B2F-C23F125CC4C3Q38535130-96AD9C75-32D8-4F31-BC33-D0ED1AD32A5DQ38606750-0457BBA7-35BB-4B2E-82E5-890BCCC0BE03Q38706387-D8884E37-9F9F-49C0-A1F9-9E517978460AQ38839225-D4BE34A2-D63F-4EC5-9080-E8F6FD3BF7D4Q39124376-8D14E757-2C79-4B3A-9BB3-74E21585A146Q39136000-41E17471-9543-4F18-9D02-1A2F081FC021Q39137143-1852AEC9-7B80-4E8D-A8F5-D59040030FCDQ39275947-B1BF63E6-3A52-40B3-A45A-548C06AEEF33Q39518323-38BA36F2-ED1E-41F5-9E1E-6250BAD80459Q39562168-20AE4214-E7C5-4EA7-98C0-F8924B2E09BA
P2860
SUMOylation of the GTPase Rac1 is required for optimal cell migration.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
SUMOylation of the GTPase Rac1 is required for optimal cell migration.
@ast
SUMOylation of the GTPase Rac1 is required for optimal cell migration.
@en
SUMOylation of the GTPase Rac1 is required for optimal cell migration.
@nl
type
label
SUMOylation of the GTPase Rac1 is required for optimal cell migration.
@ast
SUMOylation of the GTPase Rac1 is required for optimal cell migration.
@en
SUMOylation of the GTPase Rac1 is required for optimal cell migration.
@nl
prefLabel
SUMOylation of the GTPase Rac1 is required for optimal cell migration.
@ast
SUMOylation of the GTPase Rac1 is required for optimal cell migration.
@en
SUMOylation of the GTPase Rac1 is required for optimal cell migration.
@nl
P2093
P2860
P50
P356
P1433
P1476
SUMOylation of the GTPase Rac1 is required for optimal cell migration.
@en
P2093
Ellis G Jaffray
Richard C Jones
Ricky D Edmondson
P2860
P2888
P304
P356
10.1038/NCB2112
P577
2010-10-10T00:00:00Z
P5875
P6179
1035022578