Tomosyn inhibits synaptotagmin-1-mediated step of Ca2+-dependent neurotransmitter release through its N-terminal WD40 repeats.
about
Distinct initial SNARE configurations underlying the diversity of exocytosisA Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons.Arl6IP1 has the ability to shape the mammalian ER membrane in a reticulon-like fashionPositional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretionStructural and functional analysis of tomosyn identifies domains important in exocytotic regulationSyntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion.Differential interaction of tomosyn with syntaxin and SNAP25 depends on domains in the WD40 β-propeller core and determines its inhibitory activity.In vivo analysis of conserved C. elegans tomosyn domains.Phosphorylation and degradation of tomosyn-2 de-represses insulin secretion.The N- and C-terminal domains of tomosyn play distinct roles in soluble N-ethylmaleimide-sensitive factor attachment protein receptor binding and fusion regulationIdentification of rare recurrent copy number variants in high-risk autism families and their prevalence in a large ASD population.Tomosyn-dependent regulation of synaptic transmission is required for a late phase of associative odor memoryTomosyn Negatively Regulates Arginine Vasopressin Secretion in Embryonic Stem Cell-Derived Neurons.Tomosyn associates with secretory vesicles in neurons through its N- and C-terminal domains.Homozygous mutation of STXBP5L explains an autosomal recessive infantile-onset neurodegenerative disorder.The ubiquitin-proteasome system functionally links neuronal Tomosyn-1 to dendritic morphology.Tomosyn-2 is required for normal motor performance in mice and sustains neurotransmission at motor endplates.Novel Thrombotic Function of a Human SNP in STXBP5 Revealed by CRISPR/Cas9 Gene Editing in Mice.
P2860
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P2860
Tomosyn inhibits synaptotagmin-1-mediated step of Ca2+-dependent neurotransmitter release through its N-terminal WD40 repeats.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Tomosyn inhibits synaptotagmin ...... h its N-terminal WD40 repeats.
@ast
Tomosyn inhibits synaptotagmin ...... h its N-terminal WD40 repeats.
@en
type
label
Tomosyn inhibits synaptotagmin ...... h its N-terminal WD40 repeats.
@ast
Tomosyn inhibits synaptotagmin ...... h its N-terminal WD40 repeats.
@en
prefLabel
Tomosyn inhibits synaptotagmin ...... h its N-terminal WD40 repeats.
@ast
Tomosyn inhibits synaptotagmin ...... h its N-terminal WD40 repeats.
@en
P2093
P2860
P356
P1476
Tomosyn inhibits synaptotagmin ...... gh its N-terminal WD40 repeats
@en
P2093
Katsuhisa Kawai
Kenji Iwasaki
Sumiko Mochida
Takao Kurooka
Toshiaki Sakisaka
Yasunori Yamamoto
P2860
P304
40943-40955
P356
10.1074/JBC.M110.156893
P407
P577
2010-10-26T00:00:00Z