An excitable signal integrator couples to an idling cytoskeletal oscillator to drive cell migration.
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Moving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytesThe role of phosphoinositide-regulated actin reorganization in chemotaxis and cell migrationDistinct predictive performance of Rac1 and Cdc42 in cell migrationGeometry-Driven Polarity in Motile Amoeboid CellsGβ Regulates Coupling between Actin Oscillators for Cell Polarity and Directional MigrationUNC-6 (netrin) stabilizes oscillatory clustering of the UNC-40 (DCC) receptor to orient polarity.Mouse macrophages completely lacking Rho subfamily GTPases (RhoA, RhoB, and RhoC) have severe lamellipodial retraction defects, but robust chemotactic navigation and altered motility.Microtubules stabilize cell polarity by localizing rear signals.The directional response of chemotactic cells depends on a balance between cytoskeletal architecture and the external gradient.Rectified directional sensing in long-range cell migrationF-actin bundles direct the initiation and orientation of lamellipodia through adhesion-based signaling.An optogenetic system for interrogating the temporal dynamics of Akt.Fragility of foot process morphology in kidney podocytes arises from chaotic spatial propagation of cytoskeletal instability.Coupled excitable Ras and F-actin activation mediates spontaneous pseudopod formation and directed cell movementCellular memory in eukaryotic chemotaxis.Evolutionarily conserved coupling of adaptive and excitable networks mediates eukaryotic chemotaxis.Cell memory and adaptation in chemotaxis.Cell polarity: netrin calms an excitable system.Modeling self-organized spatio-temporal patterns of PIP₃ and PTEN during spontaneous cell polarization.A Model for Direction Sensing in Dictyostelium discoideum: Ras Activity and Symmetry Breaking Driven by a Gβγ-Mediated, Gα2-Ric8 -- Dependent Signal Transduction Network.Fluorescence Readout of a Patch Clamped Membrane by Laser Scanning Microscopy.Identification of a Chemoattractant G-Protein-Coupled Receptor for Folic Acid that Controls Both Chemotaxis and PhagocytosisCell Surface Mechanochemistry and the Determinants of Bleb Formation, Healing, and Travel Velocity.Chemical and mechanical stimuli act on common signal transduction and cytoskeletal networks.Self-organization of protrusions and polarity during eukaryotic chemotaxis.Directed migration of mesenchymal cells: where signaling and the cytoskeleton meet.Modeling large-scale dynamic processes in the cell: polarization, waves, and division.Intrinsic activity in cells and the brain.Dynamic membrane patterning, signal localization and polarity in living cells.Shear force-based genetic screen reveals negative regulators of cell adhesion and protrusive activity.Locally excitable Cdc42 signals steer cells during chemotaxis.Regulation of sarcoma cell migration, invasion and invadopodia formation by AFAP1L1 through a phosphotyrosine-dependent pathway.Oscillatory signatures underlie growth regimes in Arabidopsis pollen tubes: computational methods to estimate tip location, periodicity, and synchronization in growing cells.Feedback regulation between plasma membrane tension and membrane-bending proteins organizes cell polarity during leading edge formation.The Arp2/3 inhibitory protein Arpin is dispensable for chemotaxis.Crosstalk of cell polarity signaling pathways.How to understand and outwit adaptationAltering the threshold of an excitable signal transduction network changes cell migratory modesA module for Rac temporal signal integration revealed with optogenetics.Modeling Excitable Dynamics of Chemotactic Networks.
P2860
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P2860
An excitable signal integrator couples to an idling cytoskeletal oscillator to drive cell migration.
description
2013 nî lūn-bûn
@nan
2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
An excitable signal integrator ...... lator to drive cell migration.
@ast
An excitable signal integrator ...... lator to drive cell migration.
@en
type
label
An excitable signal integrator ...... lator to drive cell migration.
@ast
An excitable signal integrator ...... lator to drive cell migration.
@en
prefLabel
An excitable signal integrator ...... lator to drive cell migration.
@ast
An excitable signal integrator ...... lator to drive cell migration.
@en
P2093
P2860
P356
P1433
P1476
An excitable signal integrator ...... llator to drive cell migration
@en
P2093
Changji Shi
Peter N Devreotes
P2860
P2888
P304
P356
10.1038/NCB2859
P577
2013-10-20T00:00:00Z
P5875
P6179
1007464369