Direct evidence for BBSome-associated intraflagellar transport reveals distinct properties of native mammalian cilia.
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Specialized Cilia in Mammalian Sensory SystemsMeasuring the primary cilium length: improved method for unbiased high-throughput analysis.MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition ZoneIFT-Cargo Interactions and Protein Transport in CiliaIFT trains in different stages of assembly queue at the ciliary base for consecutive release into the cilium.SUMOylation regulates ciliary localization of olfactory signaling proteins.An Olfactory Cilia Pattern in the Mammalian Nose Ensures High Sensitivity to Odors.Loss of the BBSome perturbs endocytic trafficking and disrupts virulence of Trypanosoma brucei.Depletion of BBS Protein LZTFL1 Affects Growth and Causes Retinal Degeneration in Mice.Drosophila sensory cilia lacking MKS proteins exhibit striking defects in development but only subtle defects in adults.Open Sesame: How Transition Fibers and the Transition Zone Control Ciliary Composition.Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal.Intraflagellar transport dynein is autoinhibited by trapping of its mechanical and track-binding elements.Bardet-Biedl syndrome: Is it only cilia dysfunction?Chlamydomonas IFT25 is dispensable for flagellar assembly but required to export the BBSome from flagella.Shared and Distinct Mechanisms of Compartmentalized and Cytosolic Ciliogenesis.Pathophysiology of Olfactory Disorders and Potential Treatment Strategies.The cilium: a cellular antenna with an influence on obesity risk.The Intraflagellar Transport Machinery.Protein transport in growing and steady-state cilia.Gene Therapeutic Reversal of Peripheral Olfactory Impairment in Bardet-Biedl Syndrome.Microtubule Motors Drive Hedgehog Signaling in Primary Cilia.Photoreceptor Cilia and Retinal Ciliopathies.Intraflagellar transport: mechanisms of motor action, cooperation, and cargo delivery.Intraflagellar transport proteins 172, 80, 57, 54, 38, and 20 form a stable tubulin-binding IFT-B2 complex.Chibby functions to preserve normal ciliary morphology through the regulation of intraflagellar transport in airway ciliated cells.A motor relay on ciliary tracks.Dynamics of the IFT machinery at the ciliary tip.Trainspotting in a cilium.Functional differentiation of cooperating kinesin-2 motors orchestrates cargo import and transport in C. elegans cilia.Axonemal Lumen Dominates Cytosolic Protein Diffusion inside the Primary Cilium.Ciliary protein trafficking mediated by IFT and BBSome complexes with the aid of kinesin-2 and dynein-2 motors.A recombinant BBSome core complex and how it interacts with ciliary cargo.Olfactory loss and dysfunction in ciliopathies: Molecular mechanisms and potential therapies.The Bardet-Biedl syndrome protein complex is an adapter expanding the cargo range of intraflagellar transport trains for ciliary export.Methods for Studying Ciliary Import Mechanisms.BBS1 is involved in retrograde trafficking of ciliary GPCRs in the context of the BBSome complex.The molecular machines that traffic signaling receptors into and out of cilia.BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone.Cell-Specific α-Tubulin Isotype Regulates Ciliary Microtubule Ultrastructure, Intraflagellar Transport, and Extracellular Vesicle Biology.
P2860
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P2860
Direct evidence for BBSome-associated intraflagellar transport reveals distinct properties of native mammalian cilia.
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Direct evidence for BBSome-ass ...... ies of native mammalian cilia.
@ast
Direct evidence for BBSome-ass ...... ies of native mammalian cilia.
@en
type
label
Direct evidence for BBSome-ass ...... ies of native mammalian cilia.
@ast
Direct evidence for BBSome-ass ...... ies of native mammalian cilia.
@en
prefLabel
Direct evidence for BBSome-ass ...... ies of native mammalian cilia.
@ast
Direct evidence for BBSome-ass ...... ies of native mammalian cilia.
@en
P2093
P2860
P356
P1476
Direct evidence for BBSome-ass ...... ies of native mammalian cilia.
@en
P2093
Corey L Williams
Jeffrey R Martens
Jeremy C McIntyre
Kristen Verhey
Lian Zhang
Qinglin Pei
Stephen R Norris
P2860
P2888
P356
10.1038/NCOMMS6813
P407
P577
2014-12-15T00:00:00Z
P5875
P6179
1026550830