Direct evidence for BBSome-associated intraflagellar transport reveals distinct properties of native mammalian cilia. - Test2 - elhamkhani - TriplyDB

Direct evidence for BBSome-associated intraflagellar transport reveals distinct properties of native mammalian cilia.

Direct evidence for BBSome-associated intraflagellar transport reveals distinct properties of native mammalian cilia.

http://www.wikidata.org/entity/Q30613030

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Specialized Cilia in Mammalian Sensory Systems Measuring the primary cilium length: improved method for unbiased high-throughput analysis.MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone IFT-Cargo Interactions and Protein Transport in Cilia IFT trains in different stages of assembly queue at the ciliary base for consecutive release into the cilium.SUMOylation regulates ciliary localization of olfactory signaling proteins.An Olfactory Cilia Pattern in the Mammalian Nose Ensures High Sensitivity to Odors.Loss of the BBSome perturbs endocytic trafficking and disrupts virulence of Trypanosoma brucei.Depletion of BBS Protein LZTFL1 Affects Growth and Causes Retinal Degeneration in Mice.Drosophila sensory cilia lacking MKS proteins exhibit striking defects in development but only subtle defects in adults.Open Sesame: How Transition Fibers and the Transition Zone Control Ciliary Composition.Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal.Intraflagellar transport dynein is autoinhibited by trapping of its mechanical and track-binding elements.Bardet-Biedl syndrome: Is it only cilia dysfunction?Chlamydomonas IFT25 is dispensable for flagellar assembly but required to export the BBSome from flagella.Shared and Distinct Mechanisms of Compartmentalized and Cytosolic Ciliogenesis.Pathophysiology of Olfactory Disorders and Potential Treatment Strategies.The cilium: a cellular antenna with an influence on obesity risk.The Intraflagellar Transport Machinery.Protein transport in growing and steady-state cilia.Gene Therapeutic Reversal of Peripheral Olfactory Impairment in Bardet-Biedl Syndrome.Microtubule Motors Drive Hedgehog Signaling in Primary Cilia.Photoreceptor Cilia and Retinal Ciliopathies.Intraflagellar transport: mechanisms of motor action, cooperation, and cargo delivery.Intraflagellar transport proteins 172, 80, 57, 54, 38, and 20 form a stable tubulin-binding IFT-B2 complex.Chibby functions to preserve normal ciliary morphology through the regulation of intraflagellar transport in airway ciliated cells.A motor relay on ciliary tracks.Dynamics of the IFT machinery at the ciliary tip.Trainspotting in a cilium.Functional differentiation of cooperating kinesin-2 motors orchestrates cargo import and transport in C. elegans cilia.Axonemal Lumen Dominates Cytosolic Protein Diffusion inside the Primary Cilium.Ciliary protein trafficking mediated by IFT and BBSome complexes with the aid of kinesin-2 and dynein-2 motors.A recombinant BBSome core complex and how it interacts with ciliary cargo.Olfactory loss and dysfunction in ciliopathies: Molecular mechanisms and potential therapies.The Bardet-Biedl syndrome protein complex is an adapter expanding the cargo range of intraflagellar transport trains for ciliary export.Methods for Studying Ciliary Import Mechanisms.BBS1 is involved in retrograde trafficking of ciliary GPCRs in the context of the BBSome complex.The molecular machines that traffic signaling receptors into and out of cilia.BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone.Cell-Specific α-Tubulin Isotype Regulates Ciliary Microtubule Ultrastructure, Intraflagellar Transport, and Extracellular Vesicle Biology.

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P2860

Direct evidence for BBSome-associated intraflagellar transport reveals distinct properties of native mammalian cilia.

http://www.wikidata.org/entity/Q30613030

description

2014 nî lūn-bûn

@nan

2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Direct evidence for BBSome-ass ...... ies of native mammalian cilia.

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Direct evidence for BBSome-ass ...... ies of native mammalian cilia.

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type

label

Direct evidence for BBSome-ass ...... ies of native mammalian cilia.

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Direct evidence for BBSome-ass ...... ies of native mammalian cilia.

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Direct evidence for BBSome-ass ...... ies of native mammalian cilia.

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Direct evidence for BBSome-ass ...... ies of native mammalian cilia.

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Nature Communications

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Direct evidence for BBSome-ass ...... ies of native mammalian cilia.

@en

P2093

Corey L Williams

http://www.w3.org/2001/XMLSchema#string

Jeffrey R Martens

http://www.w3.org/2001/XMLSchema#string

Jeremy C McIntyre

http://www.w3.org/2001/XMLSchema#string

Kristen Verhey

http://www.w3.org/2001/XMLSchema#string

Lian Zhang

http://www.w3.org/2001/XMLSchema#string

Qinglin Pei

http://www.w3.org/2001/XMLSchema#string

Stephen R Norris

http://www.w3.org/2001/XMLSchema#string

P2860

The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly

BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly

Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome

The retinitis pigmentosa protein RP2 links pericentriolar vesicle transport between the Golgi and the primary cilium

BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways

A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis

Intrinsic protein-protein interaction-mediated and chaperonin-assisted sequential assembly of stable bardet-biedl syndrome protein complex, the BBSome

Mainzer-Saldino syndrome is a ciliopathy caused by IFT140 mutations

The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia

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5813

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scholarly article

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10.1038/NCOMMS6813

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5

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2014-12-15T00:00:00Z

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269774757

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1026550830

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25504142

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4284812

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