Pro-apoptotic proteins released from the mitochondria regulate the protein composition and caspase-processing activity of the native Apaf-1/caspase-9 apoptosome complex.
about
Cytosolic accumulation of HSP60 during apoptosis with or without apparent mitochondrial release: evidence that its pro-apoptotic or pro-survival functions involve differential interactions with caspase-3Hypoxia-mediated apoptosis in oral carcinoma cells occurs via two independent pathwaysJun kinase delays caspase-9 activation by interaction with the apoptosomeDifferential sensitivity to apoptosome apparatus activation in non-small cell lung carcinoma and the lungInhibitory effects of β,β-dimethylacrylshikonin on hepatocellular carcinoma in vitro and in vivo.Enhanced Hsp70 expression protects against acute lung injury by modulating apoptotic pathways.A systems biology analysis of apoptosome formation and apoptosis execution supports allosteric procaspase-9 activationPositive regulation of apoptosis by HCA66, a new Apaf-1 interacting protein, and its putative role in the physiopathology of NF1 microdeletion syndrome patients.Clinical and experimental study of oxaliplatin in treating human gastric carcinomaNecdin mediates skeletal muscle regeneration by promoting myoblast survival and differentiationIFN-gamma acts directly on activated CD4+ T cells during mycobacterial infection to promote apoptosis by inducing components of the intracellular apoptosis machinery and by inducing extracellular proapoptotic signals.Bcr-Abl-mediated protection from apoptosis downstream of mitochondrial cytochrome c release.Molecules that modulate Apaf-1 activity.Cardiolipin drives cytochrome c proapoptotic and antiapoptotic actions.Cell death controlling complexes and their potential therapeutic role.Cardiolipin-cytochrome c complex: Switching cytochrome c from an electron-transfer shuttle to a myoglobin- and a peroxidase-like heme-protein.Haeamtang induces apoptosis of colon cancer HT-29 cells through activation of caspase-3.Thymoquinone, a bioactive component of black caraway seeds, causes G1 phase cell cycle arrest and apoptosis in triple-negative breast cancer cells with mutant p53.Systems analysis of cancer cell heterogeneity in caspase-dependent apoptosis subsequent to mitochondrial outer membrane permeabilization.A novel dual signaling axis for NSP 5a3a induced apoptosis in head and neck carcinoma.Does transduced p27 induce apoptosis in human tumor cell lines?Role of cytochrome C in apoptosis: increased sensitivity to tumor necrosis factor alpha is associated with respiratory defects but not with lack of cytochrome C release.The E3 ligase PARC mediates the degradation of cytosolic cytochrome c to promote survival in neurons and cancer cells.HtrA2 deficiency causes mitochondrial uncoupling through the F₁F₀-ATP synthase and consequent ATP depletion.Acidic pH inhibits ATP depletion-induced tubular cell apoptosis by blocking caspase-9 activation in apoptosome.Proteasome inhibitor MG132 sensitizes HPV-positive human cervical cancer cells to rhTRAIL-induced apoptosis.Optimal pathways for the assembly of the Apaf-1·cytochrome c complex into apoptosome.Subcellular localization of Apaf-1 in apoptotic rat pituitary cells.Cardiolipin modulates allosterically the nitrite reductase activity of horse heart cytochrome c.Reductive nitrosylation of the cardiolipin-ferric cytochrome c complex.The Dietary Flavonoid Fisetin Causes Cell Cycle Arrest, Caspase-Dependent Apoptosis, and Enhanced Cytotoxicity of Chemotherapeutic Drugs in Triple-Negative Breast Cancer Cells.
P2860
Q24292978-87220ED8-55F8-4C93-97C5-807D31462D07Q24804177-5BC785E3-51D3-41EA-A235-F1BAB5ADA672Q28580043-CB441000-51DC-41A5-A8A6-E5D8D74BE3ADQ33637043-8073B36D-2A38-4959-8E21-B0FFF272F570Q34081177-5974D818-6167-4031-8053-8F1BBABFA0FAQ34087633-8FBBA40B-CF27-4E1F-B679-B7A858D7F35DQ34249137-04386ED8-9DE9-4E89-8DF2-982C17460053Q34611541-92A5C120-D844-4F51-97B2-BA29686FFA75Q36065649-E2D96F33-7508-413A-99AA-91457243AEC0Q36119598-2C16BEA8-58EA-4BE5-8A82-573603B34589Q36867809-00F4BF4C-C70A-45BF-A6C8-B961C7DA02F2Q37622705-246C6933-EFA1-4AEE-A898-796EBA879DEDQ37680800-7F1B26DC-4C89-46E0-8E0E-5784189659C2Q37858924-5FFA4442-FBF1-4BAA-94D0-6A70E6BC7F61Q38260863-3AF60FCA-DED3-434C-98A0-7C75670B2BAEQ38413016-6BDC8026-CE19-4F37-BAEF-E9EC32F99D6BQ38503815-11B82A94-73E4-4A95-BF30-C59569BCE50BQ39020051-21F1BF02-06B0-4657-8933-B1CD2AB07D80Q39265529-1E18C3DE-EF09-4BE2-9E93-4198C6BD2800Q39428299-24AEBEBF-9F0D-4380-9FF7-7A2D29F592DAQ40154477-84151B4E-3562-4B3F-A8C1-C8673688FE6BQ40185447-0BBCFF83-4A67-474D-A505-26F978D98A37Q42054892-0D590394-1900-4D2F-9558-E747746503A7Q42222872-87536772-BC15-4E40-B0CA-10B6DAB17EB5Q46365687-181A8A81-6BC4-47C4-A2D4-F6D2A493E7D1Q46803231-2F70F3E8-1371-4E79-A541-FDE8A171A645Q47568688-1C0C6264-9AFD-46EE-BF3D-63306A186674Q48741938-4C2BD4A5-DC89-4D0C-8090-E50340FED5C9Q52651415-2F4EAEE2-3D45-4E85-AC97-EC46F8D87D57Q53038038-72854429-B249-41FF-8921-C537919A9301Q55032232-CF8FBD07-9BF1-4605-A347-D7F5C42406C3
P2860
Pro-apoptotic proteins released from the mitochondria regulate the protein composition and caspase-processing activity of the native Apaf-1/caspase-9 apoptosome complex.
description
2004 nî lūn-bûn
@nan
2004 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մարտին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Pro-apoptotic proteins release ...... /caspase-9 apoptosome complex.
@ast
Pro-apoptotic proteins release ...... /caspase-9 apoptosome complex.
@en
type
label
Pro-apoptotic proteins release ...... /caspase-9 apoptosome complex.
@ast
Pro-apoptotic proteins release ...... /caspase-9 apoptosome complex.
@en
prefLabel
Pro-apoptotic proteins release ...... /caspase-9 apoptosome complex.
@ast
Pro-apoptotic proteins release ...... /caspase-9 apoptosome complex.
@en
P2093
P2860
P356
P1476
Pro-apoptotic proteins release ...... /caspase-9 apoptosome complex.
@en
P2093
David G Brown
Davina Twiddy
Gerald M Cohen
Kelvin Cain
Marion MacFarlane
Rebekah Jukes
P2860
P304
19665-19682
P356
10.1074/JBC.M311388200
P407
P577
2004-03-01T00:00:00Z